Patients with colorectal tumors with microsatellite instability and large deletions in HSP110 T17 have improved response to 5-fluorouracil-based chemotherapy

Gastroenterology

Volumn 146, Issue 2, 2014, Pages

  Collura, Ada ^a,b   Lagrange, Anaïs ^a,b   Svrcek, Magali ^a,b,c,d   Marisa, Laetitia ^e   Buhard, Olivier ^a,b   Guilloux, Agathe ^a,b   Wanherdrick, Kristell ^a,b   Dorard, Coralie ^a,b   Taieb, Anna ^a,b   Saget, Arnaud ^a,b   Loh, Marie ^f   Soong, Richie ^f   Zeps, Nikolajs ^g,h   Platell, Cameron ^g,h   Mews, Andrew ^g,h   Iacopetta, Barry ^h   De Thonel, Aurélie ^i,j   Seigneuric, Renaud ^i,j   Marcion, Guillaume ^i,j   Chapusot, Caroline ^k   Lepage, Come ^j   Bouvier, Anne Marie ^j   Gaub, Marie Pierre ^l   Milano, Gérard ^m   Selves, Janick ⁿ   Senet, Patrick ^o   Delarue, Patrice ^o   Arzouk, Hayat ^p,q,r   Lacoste, Claire ^p,q,r   Coquelle, Arnaud ^p,q,r   Bengrine Lefèvre, Leila ^s   Tournigand, Christophe ^s   Lefèvre, Jérémie H ^b,c   Parc, Yann ^b,c   Biard, Denis S ^t   Fléjou, Jean François ^a,b,c,d   Garrido, Carmen ^i,j,u   Duval, Alex ^a,b   more..

^a CENTRE DE RECHERCHE SAINT ANTOINE   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c HÔPITAL SAINT ANTOINE   (France)

^d UNIVERSITÉ PARIS EST   (France)

^e Programme Cartes d'Identite des Tumeurs   (France)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^g ST JOHN OF GOD HOSPITAL   (Australia)

^h UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

ⁱ Chu   (France)

^j UNIVERSITÉ DE BOURGOGNE   (France)

^k DIJON UNIVERSITY HOSPITAL   (France)

^l INSERM   (France)

^m CENTRE ANTOINE LACASSAGNE   (France)

ⁿ CANCER RESEARCH CENTER OF TOULOUSE   (France)

^o CNRS   (France)

^p INSTITUT DE RECHERCHE EN CANCÉROLOGIE DE MONTPELLIER   (France)

^q UNIV MONTPELLIER   (France)

^r CENTRE VAL D AURELLE   (France)

^s HENRI MONDOR HOSPITAL   (France)

^t CEA   (France)

^u CENTRE GEORGES FRANÇOIS LECLERC   (France)

more..

Author keywords

Outcome; Prognostic Factor; Therapeutic Response; Treatment

Indexed keywords

FLUOROURACIL; FOLINIC ACID; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 110; HEAT SHOCK PROTEIN 110DE9; OXALIPLATIN; UNCLASSIFIED DRUG;

AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; COLORECTAL CANCER; COLORECTAL TUMOR; FEMALE; GENE DELETION; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MULTIMODALITY CANCER THERAPY; MUTATIONAL ANALYSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECURRENCE FREE SURVIVAL; SURFACE PLASMON RESONANCE; TREATMENT RESPONSE; TUMOR CELL; TUMOR LOCALIZATION;

AGED; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE, TUMOR; CHEMOTHERAPY, ADJUVANT; COLECTOMY; COLORECTAL NEOPLASMS; FEMALE; FLUOROURACIL; FOLLOW-UP STUDIES; HSP110 HEAT-SHOCK PROTEINS; HUMANS; INTRONS; LEUCOVORIN; MALE; MICROSATELLITE INSTABILITY; MODELS, MOLECULAR; ORGANOPLATINUM COMPOUNDS; RETROSPECTIVE STUDIES; SEQUENCE DELETION; SURFACE PLASMON RESONANCE; SURVIVAL ANALYSIS; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 84892689375     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2013.10.054     Document Type: Article

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