The ARF tumor-suppressor controls Drosha translation to prevent Ras-driven transformation

Oncogene

Volumn 33, Issue 3, 2014, Pages 300-307

  Kuchenreuther, M J ^a   Weber, J D ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Washington University in St Louis School of Medicine   (United States)

Author keywords

ARF; Drosha; rRNA; translation; tumor suppression

Indexed keywords

ARF PROTEIN; DROSHA PROTEIN; MESSENGER RNA; MICRORNA; RAS PROTEIN; RIBOSOME RNA; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

APOPTOSIS; ARTICLE; CATALYSIS; CELL PROLIFERATION; CELL PROLIFERATION ASSAY; CELL TRANSFORMATION; CELL VIABILITY; GENE SILENCING; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; PROCESSING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TARGETING; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIBOSOME; RNA STABILITY; RNA SYNTHESIS; RNA TRANSCRIPTION; RNA TRANSLATION; TUMOR SUPPRESSOR GENE;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; EMBRYO, MAMMALIAN; FIBROBLASTS; GENE EXPRESSION; MICE; MICE, KNOCKOUT; MICRORNAS; PROTEIN BIOSYNTHESIS; RAS PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBONUCLEASE III; RNA INTERFERENCE; RNA, MESSENGER; RNA, RIBOSOMAL;

EID: 84892663170     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.601     Document Type: Article

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