-
1
-
-
0014796114
-
Stimulation and desensitization of the hypothalamic heat-sensitive structures by capsaicin in rats
-
Jancso-Gabor A, Szolcsanyi J, Jancso N (1970) Stimulation and desensitization of the hypothalamic heat-sensitive structures by capsaicin in rats. J Physiol 208: 449-459.
-
(1970)
J Physiol
, vol.208
, pp. 449-459
-
-
Jancso-Gabor, A.1
Szolcsanyi, J.2
Jancso, N.3
-
2
-
-
0014746672
-
Irreversible impairment of thermoregulation induced by capsaicin and similar pungent substances in rats and guinea-pigs
-
Jancso-Gabor A, Szolcsanyi J, Jancso N (1970) Irreversible impairment of thermoregulation induced by capsaicin and similar pungent substances in rats and guinea-pigs. J Physiol 206: 495-507.
-
(1970)
J Physiol
, vol.206
, pp. 495-507
-
-
Jancso-Gabor, A.1
Szolcsanyi, J.2
Jancso, N.3
-
3
-
-
0014128266
-
Direct evidence for neurogenic inflammation and its prevention by denervation and by pretreatment with capsaicin
-
Jancso N, Jancso-Gabor A, Szolcsanyi J (1967) Direct evidence for neurogenic inflammation and its prevention by denervation and by pretreatment with capsaicin. Br J Pharmacol Chemother 31: 138-151.
-
(1967)
Br J Pharmacol Chemother
, vol.31
, pp. 138-151
-
-
Jancso, N.1
Jancso-Gabor, A.2
Szolcsanyi, J.3
-
4
-
-
0014279741
-
The role of sensory nerve endings in neurogenic inflammation induced in human skin and in the eye and paw of the rat
-
Jancso N, Jancso-Gabor A, Szolcsanyi J (1968) The role of sensory nerve endings in neurogenic inflammation induced in human skin and in the eye and paw of the rat. Br J Pharmacol Chemother 33: 32-41.
-
(1968)
Br J Pharmacol Chemother
, vol.33
, pp. 32-41
-
-
Jancso, N.1
Jancso-Gabor, A.2
Szolcsanyi, J.3
-
5
-
-
0017640292
-
A pharmacological approach to elucidation of the role of different nerve fibres and receptor endings in mediation of pain
-
Szolcsanyi J (1977) A pharmacological approach to elucidation of the role of different nerve fibres and receptor endings in mediation of pain. J Physiol (Paris) 73: 251-259.
-
(1977)
J Physiol (Paris)
, vol.73
, pp. 251-259
-
-
Szolcsanyi, J.1
-
6
-
-
0030777012
-
The capsaicin receptor: A heat-activated ion channel in the pain pathway
-
Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, et al. (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389: 816-824.
-
(1997)
Nature
, vol.389
, pp. 816-824
-
-
Caterina, M.J.1
Schumacher, M.A.2
Tominaga, M.3
Rosen, T.A.4
Levine, J.D.5
-
7
-
-
63649126112
-
Therapeutic potential of vanilloid receptor TRPV1 agonists and antagonists as analgesics: Recent advances and setbacks
-
Wong GY, Gavva NR (2009) Therapeutic potential of vanilloid receptor TRPV1 agonists and antagonists as analgesics: Recent advances and setbacks. Brain Res Rev 60: 267-277.
-
(2009)
Brain Res Rev
, vol.60
, pp. 267-277
-
-
Wong, G.Y.1
Gavva, N.R.2
-
8
-
-
41749117999
-
Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans
-
Gavva NR, Treanor JJ, Garami A, Fang L, Surapaneni S, et al. (2008) Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans. Pain 136: 202-210.
-
(2008)
Pain
, vol.136
, pp. 202-210
-
-
Gavva, N.R.1
Treanor, J.J.2
Garami, A.3
Fang, L.4
Surapaneni, S.5
-
9
-
-
55549129906
-
NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: A randomised, double-blind study
-
Backonja M, Wallace MS, Blonsky ER, Cutler BJ, Malan P Jr, et al. (2008) NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: a randomised, double-blind study. Lancet Neurol 7: 1106-1112.
-
(2008)
Lancet Neurol
, vol.7
, pp. 1106-1112
-
-
Backonja, M.1
Wallace, M.S.2
Blonsky, E.R.3
Cutler, B.J.4
Malan Jr., P.5
-
10
-
-
68149094343
-
NGX-4010, a high-concentration capsaicin dermal patch for lasting relief of peripheral neuropathic pain
-
Noto C, Pappagallo M, Szallasi A (2009) NGX-4010, a high-concentration capsaicin dermal patch for lasting relief of peripheral neuropathic pain. Curr Opin Investig Drugs 10: 702-710.
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 702-710
-
-
Noto, C.1
Pappagallo, M.2
Szallasi, A.3
-
11
-
-
0029965156
-
Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats
-
Docherty RJ, Yeats JC, Bevan S, Boddeke HW (1996) Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats. Pflugers Archiv European journal of physiology 431: 828-837.
-
(1996)
Pflugers Archiv European Journal of Physiology
, vol.431
, pp. 828-837
-
-
Docherty, R.J.1
Yeats, J.C.2
Bevan, S.3
Boddeke, H.W.4
-
12
-
-
33644844634
-
Phosphorylation-dependent desensitization by anandamide of vanilloid receptor-1 (TRPV1) function in rat skeletal muscle arterioles and in Chinese hamster ovary cells expressing TRPV1
-
Lizanecz E, Bagi Z, Pásztor ET, Papp Z, Edes I, et al. (2006) Phosphorylation-dependent desensitization by anandamide of vanilloid receptor-1 (TRPV1) function in rat skeletal muscle arterioles and in Chinese hamster ovary cells expressing TRPV1. Molecular pharmacology 69: 1015-1023.
-
(2006)
Molecular Pharmacology
, vol.69
, pp. 1015-1023
-
-
Lizanecz, E.1
Bagi, Z.2
Pásztor, E.T.3
Papp, Z.4
Edes, I.5
-
13
-
-
17144397173
-
Regulation of Ca2+-dependent desensitization in the vanilloid receptor TRPV1 by calcineurin and cAMP-dependent protein kinase
-
Mohapatra DP, Nau C (2005) Regulation of Ca2+-dependent desensitization in the vanilloid receptor TRPV1 by calcineurin and cAMP-dependent protein kinase. The Journal of Biological Chemistry 280: 13424-13432.
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 13424-13432
-
-
Mohapatra, D.P.1
Nau, C.2
-
14
-
-
0142059776
-
Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1)
-
Bhave G, Hu HJ, Glauner KS, Zhu W, Wang H, et al. (2003) Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1). Proc Natl Acad Sci U S A 100: 12480-12485.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 12480-12485
-
-
Bhave, G.1
Hu, H.J.2
Glauner, K.S.3
Zhu, W.4
Wang, H.5
-
15
-
-
1642394771
-
Activation of protein kinase C reverses capsaicin-induced calcium-dependent desensitization of TRPV1 ion channels
-
Mandadi S, Numazaki M, Tominaga M, Bhat MB, Armati PJ, et al. (2004) Activation of protein kinase C reverses capsaicin-induced calcium-dependent desensitization of TRPV1 ion channels. Cell Calcium 35: 471-478.
-
(2004)
Cell Calcium
, vol.35
, pp. 471-478
-
-
Mandadi, S.1
Numazaki, M.2
Tominaga, M.3
Bhat, M.B.4
Armati, P.J.5
-
16
-
-
0037134417
-
Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues
-
Numazaki M, Tominaga T, Toyooka H, Tominaga M (2002) Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues. J Biol Chem 277: 13375-13378.
-
(2002)
J Biol Chem
, vol.277
, pp. 13375-13378
-
-
Numazaki, M.1
Tominaga, T.2
Toyooka, H.3
Tominaga, M.4
-
17
-
-
0037104657
-
cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation
-
Bhave G, Zhu W, Wang H, Brasier DJ, Oxford GS, et al. (2002) cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation. Neuron 35: 721-731.
-
(2002)
Neuron
, vol.35
, pp. 721-731
-
-
Bhave, G.1
Zhu, W.2
Wang, H.3
Brasier, D.J.4
Oxford, G.S.5
-
18
-
-
0346118925
-
Desensitization of capsaicin-activated currents in the vanilloid receptor TRPV1 is decreased by the cyclic AMP-dependent protein kinase pathway
-
Mohapatra DP, Nau C (2003) Desensitization of capsaicin-activated currents in the vanilloid receptor TRPV1 is decreased by the cyclic AMP-dependent protein kinase pathway. The Journal of Biological Chemistry 278: 50080-50090.
-
(2003)
The Journal of Biological Chemistry
, vol.278
, pp. 50080-50090
-
-
Mohapatra, D.P.1
Nau, C.2
-
19
-
-
0029020341
-
Long-term sensory denervation by neonatal capsaicin treatment augments sympathetic neurotransmission in rat mesenteric arteries by increasing levels of norepinephrine and selectively enhancing postjunctional actions
-
Ralevic V, Karoon P, Burnstock G (1995) Long-term sensory denervation by neonatal capsaicin treatment augments sympathetic neurotransmission in rat mesenteric arteries by increasing levels of norepinephrine and selectively enhancing postjunctional actions. J Pharmacol Exp Ther 274: 64-71.
-
(1995)
J Pharmacol Exp Ther
, vol.274
, pp. 64-71
-
-
Ralevic, V.1
Karoon, P.2
Burnstock, G.3
-
20
-
-
0018963092
-
The permanent anatomical effects of neonatal capsaicin on somatosensory nerves
-
Scadding JW (1980) The permanent anatomical effects of neonatal capsaicin on somatosensory nerves. J Anat 131: 471-482.
-
(1980)
J Anat
, vol.131
, pp. 471-482
-
-
Scadding, J.W.1
-
21
-
-
2442696310
-
Biochemical pharmacology of the vanilloid receptor TRPV1. An update
-
Cortright DN, Szallasi A (2004) Biochemical pharmacology of the vanilloid receptor TRPV1. An update. Eur J Biochem 271: 1814-1819.
-
(2004)
Eur J Biochem
, vol.271
, pp. 1814-1819
-
-
Cortright, D.N.1
Szallasi, A.2
-
22
-
-
0021028680
-
Tetrodotoxin-resistant non-cholinergic neurogenic contraction evoked by capsaicinoids and piperine on the guinea-pig trachea
-
Szolcsanyi J (1983) Tetrodotoxin-resistant non-cholinergic neurogenic contraction evoked by capsaicinoids and piperine on the guinea-pig trachea. Neurosci Lett 42: 83-88.
-
(1983)
Neurosci Lett
, vol.42
, pp. 83-88
-
-
Szolcsanyi, J.1
-
23
-
-
0033614984
-
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
-
Zygmunt PM, Petersson J, Andersson DA, Chuang H, Sørgård M, et al. (1999) Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 400: 452-457.
-
(1999)
Nature
, vol.400
, pp. 452-457
-
-
Zygmunt, P.M.1
Petersson, J.2
Andersson, D.A.3
Chuang, H.4
Sørgård, M.5
-
24
-
-
77249125805
-
The paradoxical role of the transient receptor potential vanilloid 1 receptor in inflammation
-
Alawi K, Keeble J (2010) The paradoxical role of the transient receptor potential vanilloid 1 receptor in inflammation. Pharmacology & Therapeutics 125: 181-195.
-
(2010)
Pharmacology & Therapeutics
, vol.125
, pp. 181-195
-
-
Alawi, K.1
Keeble, J.2
-
26
-
-
18044380959
-
Expression and distribution of vanilloid receptor 1 (TRPV1) in the adult rat brain
-
Toth A, Boczan J, Kedei N, Lizanecz E, Bagi Z, et al. (2005) Expression and distribution of vanilloid receptor 1 (TRPV1) in the adult rat brain. Molecular Brain Research 135: 162-168.
-
(2005)
Molecular Brain Research
, vol.135
, pp. 162-168
-
-
Toth, A.1
Boczan, J.2
Kedei, N.3
Lizanecz, E.4
Bagi, Z.5
-
27
-
-
42449141959
-
Tissue-specific regulation of microvascular diameter: Opposite functional roles of neuronal and smooth muscle located vanilloid receptor-1
-
Kark T, Bagi Z, Lizanecz E, Pásztor ET, Erdei N, et al. (2008) Tissue-specific regulation of microvascular diameter: opposite functional roles of neuronal and smooth muscle located vanilloid receptor-1. Molecular Pharmacology 73: 1405-1412.
-
(2008)
Molecular Pharmacology
, vol.73
, pp. 1405-1412
-
-
Kark, T.1
Bagi, Z.2
Lizanecz, E.3
Pásztor, E.T.4
Erdei, N.5
-
28
-
-
79955732207
-
Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells
-
Cavanaugh DJ, Chesler AT, Jackson AC, Sigal YM, Yamanaka H, et al. (2011) Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells. J Neurosci 31: 5067-5077.
-
(2011)
J Neurosci
, vol.31
, pp. 5067-5077
-
-
Cavanaugh, D.J.1
Chesler, A.T.2
Jackson, A.C.3
Sigal, Y.M.4
Yamanaka, H.5
-
29
-
-
84857488266
-
Structure-activity relationships of vanilloid receptor agonists for arteriolar TRPV1
-
Czikora Á, Lizanecz E, Bakó P, Rutkai I, Ruzsnavszky F, et al. (2012) Structure-activity relationships of vanilloid receptor agonists for arteriolar TRPV1. British Journal of Pharmacology 165: 1801-1812.
-
(2012)
British Journal of Pharmacology
, vol.165
, pp. 1801-1812
-
-
Czikora, Á.1
Lizanecz, E.2
Bakó, P.3
Rutkai, I.4
Ruzsnavszky, F.5
-
30
-
-
0029076632
-
Plasma extravasation in the skin and pelvic organs evoked by antidromic stimulation of the lumbosacral dorsal roots of the rat
-
Pinter E, Szolcsanyi J (1995) Plasma extravasation in the skin and pelvic organs evoked by antidromic stimulation of the lumbosacral dorsal roots of the rat. Neuroscience 68: 603-614.
-
(1995)
Neuroscience
, vol.68
, pp. 603-614
-
-
Pinter, E.1
Szolcsanyi, J.2
-
31
-
-
0032970173
-
Vanilloid (capsaicin) receptors and mechanisms
-
Szallasi Á, Blumberg PM (1999) Vanilloid (capsaicin) receptors and mechanisms. Pharmacological Reviews 51: 159-212.
-
(1999)
Pharmacological Reviews
, vol.51
, pp. 159-212
-
-
Szallasi, Á.1
Blumberg, P.M.2
-
32
-
-
0034646740
-
Impaired nociception and pain sensation in mice lacking the capsaicin receptor
-
Caterina MJ, Leffler A, Malmberg A, Martin W, Trafton J, et al. (2000) Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 288: 306-313.
-
(2000)
Science
, vol.288
, pp. 306-313
-
-
Caterina, M.J.1
Leffler, A.2
Malmberg, A.3
Martin, W.4
Trafton, J.5
-
33
-
-
84858073338
-
Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation
-
Czikora Á, Lizanecz E, Boczán J, Daragó A, Papp Z, et al. (2012) Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation. Life Sciences 90: 407-415.
-
(2012)
Life Sciences
, vol.90
, pp. 407-415
-
-
Czikora, Á.1
Lizanecz, E.2
Boczán, J.3
Daragó, A.4
Papp, Z.5
-
35
-
-
80052223776
-
Therapeutic targeting of TRPV1 by resiniferatoxin, from preclinical studies to clinical trials
-
Kissin I, Szallasi A (2011) Therapeutic targeting of TRPV1 by resiniferatoxin, from preclinical studies to clinical trials. Curr Top Med Chem 11: 2159-2170.
-
(2011)
Curr Top Med Chem
, vol.11
, pp. 2159-2170
-
-
Kissin, I.1
Szallasi, A.2
-
36
-
-
0034724402
-
Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human
-
Mezey E, Toth ZE, Cortright DN, Arzubi MK, Krause JE, et al. (2000) Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human. Proc Natl Acad Sci U S A 97: 3655-3660.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 3655-3660
-
-
Mezey, E.1
Toth, Z.E.2
Cortright, D.N.3
Arzubi, M.K.4
Krause, J.E.5
-
37
-
-
0019784507
-
Immunohistochemical studies on the effect of capsaicin on spinal and medullary peptide and monoamine neurons using antisera to substance P, gastrin/CCK, somatostatin, VIP, enkephalin, neurotensin and 5-hydroxytryptamine
-
Jancso G, Hokfelt T, Lundberg JM, Kiraly E, Halasz N, et al. (1981) Immunohistochemical studies on the effect of capsaicin on spinal and medullary peptide and monoamine neurons using antisera to substance P, gastrin/CCK, somatostatin, VIP, enkephalin, neurotensin and 5-hydroxytryptamine. J Neurocytol 10: 963-980.
-
(1981)
J Neurocytol
, vol.10
, pp. 963-980
-
-
Jancso, G.1
Hokfelt, T.2
Lundberg, J.M.3
Kiraly, E.4
Halasz, N.5
-
38
-
-
0018875723
-
Neurotoxic action of capsaicin on spinal substance P neurons
-
Nagy JI, Vincent SR, Staines WA, Fibiger HC, Reisine TD, et al. (1980) Neurotoxic action of capsaicin on spinal substance P neurons. Brain Res 186: 435-444.
-
(1980)
Brain Res
, vol.186
, pp. 435-444
-
-
Nagy, J.I.1
Vincent, S.R.2
Staines, W.A.3
Fibiger, H.C.4
Reisine, T.D.5
-
39
-
-
34548438441
-
Inhibitory effect of PACAP-38 on acute neurogenic and non-neurogenic inflammatory processes in the rat
-
Helyes Z, Pozsgai G, Börzsei R, Németh J, Bagoly T, et al. (2007) Inhibitory effect of PACAP-38 on acute neurogenic and non-neurogenic inflammatory processes in the rat. Peptides 28: 1847-1855.
-
(2007)
Peptides
, vol.28
, pp. 1847-1855
-
-
Helyes, Z.1
Pozsgai, G.2
Börzsei, R.3
Németh, J.4
Bagoly, T.5
-
40
-
-
0343852203
-
Anti-nociceptive effect induced by somatostatin released from sensory nerve terminals and by synthetic somatostatin analogues in the rat
-
Helyes Z, Thán M, Oroszi G, Pintér E, Németh J, et al. (2000) Anti-nociceptive effect induced by somatostatin released from sensory nerve terminals and by synthetic somatostatin analogues in the rat. Neuroscience Letters 278: 185-188.
-
(2000)
Neuroscience Letters
, vol.278
, pp. 185-188
-
-
Helyes, Z.1
Thán, M.2
Oroszi, G.3
Pintér, E.4
Németh, J.5
-
41
-
-
12844286900
-
Early painful diabetic neuropathy is associated with differential changes in the expression and function of vanilloid receptor 1
-
Hong S, Wiley JW (2005) Early painful diabetic neuropathy is associated with differential changes in the expression and function of vanilloid receptor 1. The Journal of Biological Chemistry 280: 618-627.
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 618-627
-
-
Hong, S.1
Wiley, J.W.2
-
42
-
-
34250857978
-
Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy
-
Facer P, Casula MA, Smith GD, Benham CD, Chessell IP, et al. (2007) Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy. BMC Neurology 7: 11.
-
(2007)
BMC Neurology
, vol.7
, pp. 11
-
-
Facer, P.1
Casula, M.A.2
Smith, G.D.3
Benham, C.D.4
Chessell, I.P.5
|