Hypoxic tumor environments exhibit disrupted collagen I fibers and low macromolecular transport

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Kakkad, Samata M ^a,c   Penet, Marie France ^a   Akhbardeh, Alireza ^a   Pathak, Arvind P ^a,b   Solaiyappan, Meiyappan ^a   Raman, Venu ^a,b   Leibfritz, Dieter ^c   Glunde, Kristine ^a,b   Bhujwalla, Zaver M ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c UNIVERSITY OF BREMEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN FIBER; COLLAGEN TYPE 1; RED FLUORESCENT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOENGINEERING; BREAST CANCER; CANCER CELL; CANCER MODEL; CELL HYPOXIA; CELL STRAIN; CELL STRAIN MDA MB 231; CONTROLLED STUDY; DISEASE SEVERITY; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN CELL; MACROMOLECULE; MOUSE; NONHUMAN; PROTEIN DEFECT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TUMOR ESCAPE; TUMOR MICROENVIRONMENT; TUMOR XENOGRAFT;

ANIMALS; ANOXIA; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; BREAST NEOPLASMS; CELL ENGINEERING; CELL LINE, TUMOR; COLLAGEN TYPE I; EXTRACELLULAR MATRIX; FEMALE; GENES, REPORTER; HUMANS; LUMINESCENT PROTEINS; MAGNETIC RESONANCE IMAGING; MICE; MICE, SCID; MICROSCOPY, FLUORESCENCE; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; TRANSPLANTATION, HETEROLOGOUS; TUMOR MICROENVIRONMENT;

EID: 84892618351     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081869     Document Type: Article

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