Thrifty metabolic programming in rats is induced by both maternal undernutrition and postnatal leptin treatment, but masked in the presence of both: Implications for models of developmental programming

BMC Genomics

Volumn 15, Issue 1, 2014, Pages

  Ellis, Peter J I ^a   Morris, Tiffany J ^a,b   Skinner, Benjamin M ^a   Sargent, Carole A ^a   Vickers, Mark H ^c   Gluckman, Peter D ^c   Gilmour, Stewart ^c   Affara, Nabeel A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Antigen presentation; Development; Fetal programming; Inflammation; Leptin; Obesity; Thrifty phenotype

Indexed keywords

LEPTIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TRANSCRIPTOME;

ADAPTIVE IMMUNITY; AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; DOWN REGULATION; FEMALE; FETUS DEVELOPMENT; INFLAMMATION; MALNUTRITION; MATERNAL NUTRITION; METABOLISM; MICROARRAY ANALYSIS; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PERINATAL PERIOD; RAT; RNA TRANSCRIPTION;

RATTUS;

AMINO ACIDS; ANIMALS; CARBOHYDRATE METABOLISM; DIET; DISEASE MODELS, ANIMAL; FEMALE; FETAL DEVELOPMENT; FETAL NUTRITION DISORDERS; HISTOCOMPATIBILITY ANTIGENS CLASS I; INFLAMMATION MEDIATORS; LEPTIN; LIVER; MALE; OBESITY; OXIDATIVE STRESS; PHENOTYPE; PREGNANCY; RATS; RATS, WISTAR; TRANSCRIPTOME;

EID: 84892606570     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-15-49     Document Type: Article

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