Antigen-induced mast cell expansion and bronchoconstriction in a mouse model of asthma

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 306, Issue 2, 2014, Pages

  Li, Shannon ^a   Aliyeva, Minara ^a   Daphtary, Nirav ^a   Martin, Rebecca A ^a   Poynter, Matthew E ^a   Kostin, Shannon F ^a   Van Der Velden, Jos L ^a   Hyman, Alexandra M ^a   Stevenson, Christopher S ^b   Phillips, Jonathan E ^b   Lundblad, Lennart K A ^a  

^a UNIVERSITY OF VERMONT   (United States)

^b HOFFMANN LA ROCHE INC   (United States)

Author keywords

Histamine; Input impedance; Mast cell protease 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CYTOKINE; GAMMA INTERFERON; HISTAMINE; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 5; MAST CELL PROTEASE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ASTHMA; BRONCHOCONSTRICTION; CELL DIFFERENTIATION; CELL EXPANSION; CONTROLLED STUDY; FEMALE; HISTOLOGY; LUNG LAVAGE; LUNG PARENCHYMA; LUNG VOLUME; MAST CELL; MASTOCYTOSIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TOTAL LUNG CAPACITY;

HISTAMINE; INPUT IMPEDANCE; MAST CELL PROTEASE-1;

ANIMALS; ANTIGENS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOCONSTRICTION; CELL DEGRANULATION; DISEASE MODELS, ANIMAL; FEMALE; MALE; MAST CELLS; MASTOCYTOSIS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MODELS, BIOLOGICAL; P-METHOXY-N-METHYLPHENETHYLAMINE; PYROGLYPHIDAE;

EID: 84892604421     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00055.2013     Document Type: Article

References (53)

1. Aldenborg F, Enerback L. Thymus dependence of connective tissue mast cells: a quantitative cytofluorometric study of the growth of peritoneal mast cells in normal and athymic rats. Int Arch Allergy Appl Immunol 78: 277-282, 1985.
2. Alkhouri H, Hollins F, Moir LM, Brightling CE, Armour CL, Hughes JM. Human lung mast cells modulate the functions of airway smooth muscle cells in asthma. Allergy 66: 1231-1241, 2011.
3. Amin K. The role of mast cells in allergic inflammation. Respir Med 106: 9-14, 2012.
4. Bates JH, Allen GB. The estimation of lung mechanics parameters in the presence of pathology: a theoretical analysis. Ann Biomed Engineering 34: 384-392, 2006.
5. Bates JH, Lauzon AM. Modeling the oscillation dynamics of activated airway smooth muscle strips. Am J Physiol Lung Cell Mol Physiol 289: L849-L855, 2005.
6. Bates JH, Suki B. Assessment of peripheral lung mechanics. Respir Physiol Neurobiol 163: 54-63, 2008.
7. Bates JH, Wagers SS, Norton RJ, Rinaldi LM, Irvin CG. Exaggerated airway narrowing in mice treated with intratracheal cationic protein. J Appl Physiol 100: 500-506, 2006.
8. Bates JHT, Lauzon AM. Parenchymal tethering, airway wall stiffness, and the dynamics of bronchoconstriction. J Appl Physiol 102: 1912-1920, 2007.
9. Bates JHT, Lutchen KR. The interface between measurement and modeling of peripheral lung mechanics. Respir Physiol Neurobiol 148: 153-164, 2005.
10. Burton OT, Oettgen HC. Beyond immediate hypersensitivity: evolving roles for IgE antibodies in immune homeostasis and allergic diseases. Immunol Rev 242: 128-143, 2011.
11. Cates EC, Fattouh R, Wattie J, Inman MD, Goncharova S, Coyle AJ, Gutierrez-Ramos JC, Jordana M. Intranasal exposure of mice to house dust mite elicits allergic airway inflammation via a GM-CSF-mediated mechanism. J Immunol 173: 6384-6392, 2004.
12. Chahdi A, Fraundorfer PF, Beaven MA. Compound 48/80 activates mast cell phospholipase D via heterotrimeric GTP-binding proteins. J Pharmacol Exp Ther 292: 122-130, 2000.
13. Daan de Boer J, Roelofs JJ, de Vos AF, de Beer R, Schouten M, Hommes TJ, Hoogendijk AJ, de Boer OJ, Stroo I, van der Zee JS, Veer CV, van der Poll T. Lipopolysaccharide inhibits Th2 lung inflammation induced by house dust mite allergens in mice. Am J Respir Cell Mol Biol 48: 382-389, 2013.
14. Dahlback M, Brattsand R. Antigen-induced bronchial anaphylaxis in actively sensitized SD rats. Effects of local treatment with anti-asthmatic drugs. Allergy 41: 594-602, 1986.
15. Finney MJ, Forsberg KI. Quantification of nasal involvement in a guinea pig plethysmograph. J Appl Physiol 76: 1432-1438, 1994.
16. Gilfillan AM, Austin SJ, Metcalfe DD. Mast cell biology: introduction and overview. Adv Exp Med Biol 716: 2-12, 2011.
17. Gotzsche PC, Johansen HK, Burr ML, Hammarquist C. House dust mite control measures for asthma. Cochrane Database Syst Rev CD001187, 2001.
18. Gregory LG, Lloyd CM. Orchestrating house dust mite-associated allergy in the lung. Trends Immunol 32: 402-411, 2011.
19. Hantos Z, Daroczy B, Suki B, Nagy S, Fredberg JJ. Input impedance and peripheral inhomogeneity of dog lungs. J Appl Physiol 72: 168-178, 1992.
20. Hessel EM, Van Oosterhout AJ, Hofstra CL, De Bie JJ, Garssen J, Van Loveren H, Verheyen AK, Savelkoul HF, Nijkamp FP. Broncho-constriction and airway hyperresponsiveness after ovalbumin inhalation in sensitized mice. Eur J Pharmacol 293: 401-412, 1995.
21. Holt PG, Batty JE, Turner KJ. Inhibition of specific IgE responses in mice by pre-exposure to inhaled antigen. Immunology 42: 409-417, 1981.
22. Hsiue TR, Lei HY, Hsieh AL, Wang TY, Chang HY, Chen CR. Mite-induced allergic airway inflammation in guinea pigs. Int Arch Allergy Immunol 112: 295-302, 1997.
23. Lagunoff D, Martin TW, Read G. Agents that release histamine from mast cells. Annu Rev Pharmacol Toxicol 23: 331-351, 1983.
24. Llop-Guevara A, Colangelo M, Chu DK, Moore CL, Stieber NA, Walker TD, Goncharova S, Coyle AJ, Lundblad LK, O'Byrne PM, Lovric M, Jordana M. In vivo-to-in silico iterations to investigate aeroallergen-host interactions. PLoS ONE 3: e2426, 2008.
25. Lundblad KAL, Allen G, Thompson-Figueroa J, Bates JHT. Airway closure during bronchoconstriction in mice confirmed with micro-CT (Abstract). Proc Am Thoracic Soc 2: A564, 2005.
26. Lundblad LK, Rinaldi LM, Poynter ME, Riesenfeld EP, Wu M, Aimi S, Barone LM, Bates JH, Irvin CG. Detrimental effects of albuterol on airway responsiveness requires airway inflammation and is independent of beta-receptor affinity in murine models of asthma (Abstract). Respir Res 12: 27, 2011.
27. Lundblad LKA, Irvin CG, Adler A, Bates JH. A reevaluation of the validity of unrestrained plethysmography in mice. J Appl Physiol 93: 1198-1207, 2002.
28. Lundblad LKA, Li S, Aliyeva M, Daphtary M, Van der Velden J, Hoffman MS, Lahue BS, Janssen-Heininger YMV, Poynter ME, Bates JHT, Stevenson CS, Phillips JE. Bronchoconstriction in mice allergic to house dust mite; a role for mast cells? (Abstract) Am J Respir Crit Care Med 185: A2405, 2012.
29. Lundblad LKA, Thompson-Figueroa J, Allen GB, Rinaldi L, Norton RJ, Irvin CG, Bates JH. Airway hyperresponsiveness in allergically inflamed mice: the role of airway closure. Am J Respir Crit Care Med 175: 768-774, 2007.
30. Marks GB. House dust mite exposure as a risk factor for asthma: benefits of avoidance. Allergy 53: 108-114, 1998.
31. Mayrhofer G, Fisher R. Mast cells in severely T-cell depleted rats and the response to infestation with Nippostrongylus brasiliensis. Immunology 37: 145-155, 1979.
32. Metcalfe DD, Baram D, Mekori YA. Mast cells. Physiol Rev 77: 1033-1079, 1997.
33. Molinari JF, Scuri M, Moore WR, Clark J, Tanaka R, Abraham WM. Inhaled tryptase causes bronchoconstriction in sheep via histamine release. Am J Respir Crit Care Med 154: 649-653, 1996.
34. Moore ML, Newcomb DC, Parekh VV, Van Kaer L, Collins RD, Zhou W, Goleniewska K, Chi MH, Mitchell D, Boyce JA, Durbin JE, Sturkie C, Peebles RS Jr. STAT1 negatively regulates lung basophil IL-4 expression induced by respiratory syncytial virus infection. J Immunol 183: 2016-2026, 2009.
35. Nials AT, Uddin S. Mouse models of allergic asthma: acute and chronic allergen challenge. Dis Models Mechanisms 1: 213-220, 2008.
36. Pae S, Cho JY, Dayan S, Miller M, Pemberton AD, Broide DH. Chronic allergen challenge induces bronchial mast cell accumulation in BALB/c but not C57BL/6 mice and is independent of IL-9. Immunoge-netics 62: 499-506, 2010.
37. Page S, Ammit AJ, Black JL, Armour CL. Human mast cell and airway smooth muscle cell interactions: implications for asthma. Am J Physiol Lung Cell Mol Physiol 281: L1313-L1323, 2001.
38. Phillips JE, Peng R, Harris P, Burns L, Renteria L, Lundblad LK, Fine JS, Bauer CM, Stevenson CS. House dust mite models: will they translate clinically as a superior model of asthma? J Allergy Clin Immunol 132: 242-244, 2013.
39. Ray P, Krishnamoorthy N, Ray A. Emerging functions of c-kit and its ligand stem cell factor in dendritic cells: regulators of T cell differentiation. Cell Cycle 7: 2826-2832, 2008.
40. Riesenfeld E, Allen GB, Bates JH, Poynter ME, Wu M, Aimi S, Lundblad LK. The temporal evolution of airways hyperresponsiveness and inflammation. J Allergy Ther 1: 1-7, 2012.
41. Rothschild AM. Mechanisms of histamine release by compound 48-80. Br J Pharmacol 38: 253-262, 1970.
42. Ryu JH, Yoo JY, Kim MJ, Hwang SG, Ahn KC, Ryu JC, Choi MK, Joo JH, Kim CH, Lee SN, Lee WJ, Kim J, Shin DM, Kweon MN, Bae YS, Yoon JH. Distinct TLR-mediated pathways regulate house dust mite-induced allergic disease in the upper and lower airways. J Allergy Clin Immunol 131: 549-561, 2013.
43. Schuessler T, Bates J. A computer-controlled research ventilator for small animals: design and evaluation. IEEE Trans Bio-medical Engineering 42: 860-866, 1995.
44. Shirai T, Yasueda H, Saito A, Taniguchi M, Akiyama K, Tsuchiya T, Suda T, Chida K. Effect of exposure and sensitization to indoor allergens on asthma control level. Allergology Int 61: 51-56, 2012.
45. Stevens RL, Austen KF. Recent advances in the cellular and molecular biology of mast cells. Immunol Today 10: 381-386, 1989.
46. Swirski FK, Gajewska BU, Alvarez D, Ritz SA, Cundall MJ, Cates EC, Coyle AJ, Gutierrez-Ramos JC, Inman MD, Jordana M, Stampfli MR. Inhalation of a harmless antigen (ovalbumin) elicits immune activation but divergent immunoglobulin and cytokine activities in mice. Clin Exp Allergy 32: 411-421, 2002.
47. Tomioka S, Bates JH, Irvin CG. Airway and tissue mechanics in a murine model of asthma: alveolar capsule vs. forced oscillations. J Appl Physiol 93: 263-270, 2002.
48. Trompette A, Divanovic S, Visintin A, Blanchard C, Hegde RS, Madan R, Thorne PS, Wills-Karp M, Gioannini TL, Weiss JP, Karp CL. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 457: 585-588, 2009.
49. van den Berge M, Kerstjens HA, Postma DS. Provocation with aden-osine 5=-monophosphate as a marker of inflammation in asthma, allergic rhinitis and chronic obstructive pulmonary disease. Clin Exp Allergy 32: 824-830, 2002.
50. Wagers S, Lundblad LKA, Ekman M, Irvin CG, Bates JHT. The allergic mouse model of asthma: normal smooth muscle in an abnormal lung? J Appl Physiol 96: 2019-2027, 2004.
51. Wagers SS, Haverkamp HC, Bates JH, Norton RJ, Thompson-Figueroa JA, Sullivan MJ, Irvin CG. Intrinsic and antigen-induced airway hyperresponsiveness are the result of diverse physiological mechanisms. J Appl Physiol 102: 221-230, 2007.
52. Wilson RH, Whitehead GS, Nakano H, Free ME, Kolls JK, Cook DN. Allergic sensitization through the airway primes th17-dependent neutro-philia and airway hyperresponsiveness. Am J Respir Crit Care Med 180: 720-730, 2009.
53. Zosky GR, Larcombe AN, White OJ, Burchell JT, Janosi TZ, Hantos Z, Holt PG, Sly PD, Turner DJ. Ovalbumin-sensitized mice are good models for airway hyperresponsiveness but not acute physiological responses to allergen inhalation. Clin Exp Allergy 38:829-838, 2008.