메뉴 건너뛰기




Volumn 29, Issue 1, 2014, Pages 38-45

Association of ADRA2A and MTHFR gene polymorphisms with weight loss following antipsychotic switching to aripiprazole or ziprasidone

Author keywords

1291C G adrenergic receptor; 1298A C methylenetetrahydrofolate reductase; antipsychotic induced weight gain; aripiprazole; schizophrenia; ziprasidone

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ALPHA 2A ADRENERGIC RECEPTOR; ARIPIPRAZOLE; CHLORPROMAZINE; FLUPENTIXOL; FLUPHENAZINE; NEUROLEPTIC AGENT; OLANZAPINE; PALIPERIDONE; QUETIAPINE; RISPERIDONE; SULPIRIDE; TRIFLUOPERAZINE; ZIPRASIDONE;

EID: 84892593544     PISSN: 08856222     EISSN: 10991077     Source Type: Journal    
DOI: 10.1002/hup.2366     Document Type: Article
Times cited : (12)

References (47)
  • 1
    • 0032751075 scopus 로고    scopus 로고
    • Antipsychotic-induced weight gain: A comprehensive research synthesis
    • Allison DB, Mentore JL, Heo M, et al,. 1999. Antipsychotic-induced weight gain: a comprehensive research synthesis. Am J Psychiatry 156: 1686-1696.
    • (1999) Am J Psychiatry , vol.156 , pp. 1686-1696
    • Allison, D.B.1    Mentore, J.L.2    Heo, M.3
  • 2
    • 69549090006 scopus 로고    scopus 로고
    • Efficacy and tolerability of switching to ziprasidone from olanzapine, risperidone or haloperidol: An international, multicenter study
    • Alptekin K, Hafez J, Brook S, et al,. 2009. Efficacy and tolerability of switching to ziprasidone from olanzapine, risperidone or haloperidol: an international, multicenter study. Int Clin Psychopharmacol 24: 229-238.
    • (2009) Int Clin Psychopharmacol , vol.24 , pp. 229-238
    • Alptekin, K.1    Hafez, J.2    Brook, S.3
  • 3
    • 84870469320 scopus 로고    scopus 로고
    • American Psychiatric Association. 4th edn, text revision. American Psychiatric Association: Washington, DC
    • American Psychiatric Association. 2000. Diagnostic and Statistical Manual of Mental Disorders, 4th edn, text revision. American Psychiatric Association: Washington, DC.
    • (2000) Diagnostic and Statistical Manual of Mental Disorders
  • 4
    • 0026516804 scopus 로고
    • Adrenergic receptor function in fat cells
    • Arner P,. 1992. Adrenergic receptor function in fat cells. Am J Clin Nutr 55: 228S-236S.
    • (1992) Am J Clin Nutr , vol.55
    • Arner, P.1
  • 5
    • 0032906750 scopus 로고    scopus 로고
    • Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: Metabolic significance, risks and impact on folate requirement
    • Bailey LB, Gregory JF,. 1999. Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement. J Nutr 129 (5): 919-922.
    • (1999) J Nutr , vol.129 , Issue.5 , pp. 919-922
    • Bailey, L.B.1    Gregory, J.F.2
  • 6
    • 36749070913 scopus 로고    scopus 로고
    • Possible association of the pro-melanin-concentrating hormone gene with a greater body mass index as a side effect of the antipsychotic olanzapine
    • Chagnon YC, Bureau A, Gendron D, et al,. 2007. Possible association of the pro-melanin-concentrating hormone gene with a greater body mass index as a side effect of the antipsychotic olanzapine. Am J Med Genet B Neuropsychiatr Genet 144B: 1063-1069.
    • (2007) Am J Med Genet B Neuropsychiatr Genet , vol.144 B , pp. 1063-1069
    • Chagnon, Y.C.1    Bureau, A.2    Gendron, D.3
  • 7
    • 84864186018 scopus 로고    scopus 로고
    • Comparative effectiveness of switching antipsychotic drug treatment to aripiprazole or ziprasidone for improving metabolic profile and atherogenic dyslipidaemia: A 12-month, prospective, open-label study
    • Chen Y, Bobo WV, Watts K, Jayathilake K, Tang T, Meltzer HY,. 2012. Comparative effectiveness of switching antipsychotic drug treatment to aripiprazole or ziprasidone for improving metabolic profile and atherogenic dyslipidaemia: A 12-month, prospective, open-label study. J Psychopharmacol 26: 1201-1210.
    • (2012) J Psychopharmacol , vol.26 , pp. 1201-1210
    • Chen, Y.1    Bobo, W.V.2    Watts, K.3    Jayathilake, K.4    Tang, T.5    Meltzer, H.Y.6
  • 8
    • 82555176502 scopus 로고    scopus 로고
    • Association of the ADRA1A gene and the severity of metabolic abnormalities in patients with schizophrenia
    • Cheng C, Chiu HJ, Loh EW, et al,. 2012. Association of the ADRA1A gene and the severity of metabolic abnormalities in patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 36: 205-210.
    • (2012) Prog Neuropsychopharmacol Biol Psychiatry , vol.36 , pp. 205-210
    • Cheng, C.1    Chiu, H.J.2    Loh, E.W.3
  • 9
    • 0033778106 scopus 로고    scopus 로고
    • Similarities in the action of Ro 60-0175: A 5-HT2C receptor agonist and D-fenfluramine on feeding patterns in the rat
    • Clifton PG, Lee MD, Dourish CT,. 2000. Similarities in the action of Ro 60-0175: A 5-HT2C receptor agonist and D-fenfluramine on feeding patterns in the rat. Psychopharmacology (Berl) 152: 256-267.
    • (2000) Psychopharmacology (Berl) , vol.152 , pp. 256-267
    • Clifton, P.G.1    Lee, M.D.2    Dourish, C.T.3
  • 10
    • 77954218128 scopus 로고    scopus 로고
    • Potential mechanisms of atypical antipsychotic-induced metabolic derangement: Clues for understanding obesity and novel drug design
    • Coccurello R, Moles A,. 2010. Potential mechanisms of atypical antipsychotic-induced metabolic derangement: Clues for understanding obesity and novel drug design. Pharmacol Ther 127: 210-251.
    • (2010) Pharmacol Ther , vol.127 , pp. 210-251
    • Coccurello, R.1    Moles, A.2
  • 12
    • 0034000526 scopus 로고    scopus 로고
    • Effects of selected serotonin 5-HT(1) and 5HT(2) receptor agonists on feeding behavior: Possible mechanisms of action
    • De Vry J, Schreiber R,. 2000. Effects of selected serotonin 5-HT(1) and 5HT(2) receptor agonists on feeding behavior: possible mechanisms of action. Neurosci Biobehav Rev 24: 341-353.
    • (2000) Neurosci Biobehav Rev , vol.24 , pp. 341-353
    • De Vry, J.1    Schreiber, R.2
  • 13
    • 84856267575 scopus 로고    scopus 로고
    • Cardiometabolic risk and the MTHFR C677T variant in children treated with second-generation antipsychotics
    • Devlin AM, Ngai YF, Ronsley R, Panagiotopoulos C,. 2012. Cardiometabolic risk and the MTHFR C677T variant in children treated with second-generation antipsychotics. Transl Psychiatry 2: e71.
    • (2012) Transl Psychiatry , vol.2
    • Devlin, A.M.1    Ngai, Y.F.2    Ronsley, R.3    Panagiotopoulos, C.4
  • 14
    • 0022383491 scopus 로고
    • Characteristics of feeding induced by the serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT)
    • Dourish CT, Hutson PH, Curzon G,. 1985. Characteristics of feeding induced by the serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT). Brain Res Bull 15: 377-384.
    • (1985) Brain Res Bull , vol.15 , pp. 377-384
    • Dourish, C.T.1    Hutson, P.H.2    Curzon, G.3
  • 15
    • 36849066949 scopus 로고    scopus 로고
    • Metabolic syndrome and insulin resistance in schizophrenia patients receiving antipsychotics genotyped for the methylenetetrahydrofolate reductase (MTHFR) 677C/T and 1298A/C variants
    • Ellingrod VL, Miller DD, Taylor SF, Moline J, Holman T, Kerr J,. 2008. Metabolic syndrome and insulin resistance in schizophrenia patients receiving antipsychotics genotyped for the methylenetetrahydrofolate reductase (MTHFR) 677C/T and 1298A/C variants. Schizophr Res 98: 47-54.
    • (2008) Schizophr Res , vol.98 , pp. 47-54
    • Ellingrod, V.L.1    Miller, D.D.2    Taylor, S.F.3    Moline, J.4    Holman, T.5    Kerr, J.6
  • 16
    • 2342631335 scopus 로고    scopus 로고
    • S-adenosylmethionine: Nothing goes to waste
    • Fontecave M, Atta M, Mulliez E,. 2004. S-adenosylmethionine: nothing goes to waste. Trends Biochem Sci 29: 243-249.
    • (2004) Trends Biochem Sci , vol.29 , pp. 243-249
    • Fontecave, M.1    Atta, M.2    Mulliez, E.3
  • 17
    • 0035982901 scopus 로고    scopus 로고
    • The Alpha2-adrenergic receptor gene and body Fat content and distribution: The HERITAGE family study
    • Garenc C, Pérusse L, Chagnon YC, et al,. 2002. The Alpha2-adrenergic receptor gene and body Fat content and distribution: the HERITAGE family study. Mol Med 8: 88-94.
    • (2002) Mol Med , vol.8 , pp. 88-94
    • Garenc, C.1    Pérusse, L.2    Chagnon, Y.C.3
  • 18
    • 79959436585 scopus 로고    scopus 로고
    • Polymorphisms of the LEP, LEPR and HTR2C gene: Obesity and BMI change in patients using antipsychotic medication in a naturalistic setting
    • Gregoor JG, van der Weide J, Loovers HM, van Megen HJ, Egberts TC, Heerdink ER,. 2011. Polymorphisms of the LEP, LEPR and HTR2C gene: obesity and BMI change in patients using antipsychotic medication in a naturalistic setting. Pharmacogenomics 12: 919-923.
    • (2011) Pharmacogenomics , vol.12 , pp. 919-923
    • Gregoor, J.G.1    Van Der Weide, J.2    Loovers, H.M.3    Van Megen, H.J.4    Egberts, T.C.5    Heerdink, E.R.6
  • 19
    • 27444443876 scopus 로고    scopus 로고
    • Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
    • Grundy SM, Cleeman JI, Daniels SR, et al,. 2005. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, And Blood Institute Scientific Statement. Circulation 112: 2735-2752.
    • (2005) Circulation , vol.112 , pp. 2735-2752
    • Grundy, S.M.1    Cleeman, J.I.2    Daniels, S.R.3
  • 21
    • 78951469329 scopus 로고    scopus 로고
    • Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia
    • Jassim G, Ferno J, Theisen FM, et al,. 2011. Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia. Pharmacopsychiatry 44: 15-20.
    • (2011) Pharmacopsychiatry , vol.44 , pp. 15-20
    • Jassim, G.1    Ferno, J.2    Theisen, F.M.3
  • 22
    • 77953162615 scopus 로고    scopus 로고
    • Effectiveness of switching from aripiprazole to ziprasidone in patients with schizophrenia
    • Kim SW, Shin IS, Kim JM, Bae KY, Yang SJ, Yoon JS,. 2010. Effectiveness of switching from aripiprazole to ziprasidone in patients with schizophrenia. Clin Neuropharmacol 33: 121-125.
    • (2010) Clin Neuropharmacol , vol.33 , pp. 121-125
    • Kim, S.W.1    Shin, I.S.2    Kim, J.M.3    Bae, K.Y.4    Yang, S.J.5    Yoon, J.S.6
  • 23
    • 80755163168 scopus 로고    scopus 로고
    • Polymorphisms of INSIG2, MC4R, and LEP are associated with obesity- and metabolic-related traits in schizophrenic patients
    • Kuo PH, Kao CF, Chen PY, et al,. 2011. Polymorphisms of INSIG2, MC4R, and LEP are associated with obesity- and metabolic-related traits in schizophrenic patients. J Clin Psychopharmacol 31: 705-711.
    • (2011) J Clin Psychopharmacol , vol.31 , pp. 705-711
    • Kuo, P.H.1    Kao, C.F.2    Chen, P.Y.3
  • 24
    • 0032543167 scopus 로고    scopus 로고
    • Effects of intracerebroventricularly infused histamine and selective H1, H2 and H3 agonists on food and water intake and urine flow in Wistar rats
    • Lecklin A, Etu-Seppala P, Stark H, Tuomisto L,. 1998. Effects of intracerebroventricularly infused histamine and selective H1, H2 and H3 agonists on food and water intake and urine flow in Wistar rats. Brain Res 793: 279-288.
    • (1998) Brain Res , vol.793 , pp. 279-288
    • Lecklin, A.1    Etu-Seppala, P.2    Stark, H.3    Tuomisto, L.4
  • 26
    • 33744967315 scopus 로고    scopus 로고
    • Do allelic variants in alpha2A and alpha2C adrenergic receptors predispose to hypertension in blacks?
    • Li JL, Canham RM, Vongpatanasin W, Leonard D, Auchus RJ, Victor RG,. 2006. Do allelic variants in alpha2A and alpha2C adrenergic receptors predispose to hypertension in blacks? Hypertension 47: 1140-1146.
    • (2006) Hypertension , vol.47 , pp. 1140-1146
    • Li, J.L.1    Canham, R.M.2    Vongpatanasin, W.3    Leonard, D.4    Auchus, R.J.5    Victor, R.G.6
  • 27
    • 0034158310 scopus 로고    scopus 로고
    • Weight gain associated with psychotropic drugs
    • Masand PS,. 2000. Weight gain associated with psychotropic drugs. Expert Opin Pharmacother 1: 377-389.
    • (2000) Expert Opin Pharmacother , vol.1 , pp. 377-389
    • Masand, P.S.1
  • 28
    • 12344326514 scopus 로고    scopus 로고
    • Treatments for schizophrenia: A critical review of pharmacology and mechanisms of action of antipsychotic drugs
    • Miyamoto S, Duncan GE, Marx CE, Lieberman JA,. 2005. Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs. Mol Psychiatry 10: 79-104.
    • (2005) Mol Psychiatry , vol.10 , pp. 79-104
    • Miyamoto, S.1    Duncan, G.E.2    Marx, C.E.3    Lieberman, J.A.4
  • 29
    • 33846850178 scopus 로고    scopus 로고
    • Improvement in antipsychotic-related metabolic disturbances in patients with schizophrenia switched to ziprasidone
    • Montes JM, Rodriguez JL, Balbo E, et al,. 2007. Improvement in antipsychotic-related metabolic disturbances in patients with schizophrenia switched to ziprasidone. Prog Neuropsychopharmacol Biol Psychiatry 31: 383-388.
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.31 , pp. 383-388
    • Montes, J.M.1    Rodriguez, J.L.2    Balbo, E.3
  • 30
    • 84868483214 scopus 로고    scopus 로고
    • Review article: Weight gain, schizophrenia and antipsychotics: New findings from animal model and pharmacogenomic studies
    • Panariello F, De Luca V, De Bartolomeis A,. 2011. Review article: weight gain, schizophrenia and antipsychotics: New findings from animal model and pharmacogenomic studies. Schizophr Res Treatment 2011: 459284.
    • (2011) Schizophr Res Treatment , vol.2011 , pp. 459284
    • Panariello, F.1    De Luca, V.2    De Bartolomeis, A.3
  • 31
    • 33745013199 scopus 로고    scopus 로고
    • Weight gain associated with the alpha2a-adrenergic receptor -1291 C/G polymorphism and olanzapine treatment
    • Park YM, Chung YC, Lee SH, et al,. 2006. Weight gain associated with the alpha2a-adrenergic receptor -1291 C/G polymorphism and olanzapine treatment. Am J Med Genet B Neuropsychiatr Genet 141B: 394-397.
    • (2006) Am J Med Genet B Neuropsychiatr Genet , vol.141 B , pp. 394-397
    • Park, Y.M.1    Chung, Y.C.2    Lee, S.H.3
  • 32
    • 84865822927 scopus 로고    scopus 로고
    • Pharmacogenetic aspects of antipsychotic drug-induced weight gain - A critical review
    • Reynolds GP,. 2012. Pharmacogenetic aspects of antipsychotic drug-induced weight gain-a critical review. Clin Psychopharmacol Neurosci 10: 71-77.
    • (2012) Clin Psychopharmacol Neurosci , vol.10 , pp. 71-77
    • Reynolds, G.P.1
  • 33
    • 72149090641 scopus 로고    scopus 로고
    • Metabolic side effects of antipsychotic drug treatment - Pharmacological mechanisms
    • Reynolds GP, Kirk SL,. 2010. Metabolic side effects of antipsychotic drug treatment-pharmacological mechanisms. Pharmacol Ther 125: 169-179.
    • (2010) Pharmacol Ther , vol.125 , pp. 169-179
    • Reynolds, G.P.1    Kirk, S.L.2
  • 34
    • 0037097014 scopus 로고    scopus 로고
    • Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism
    • Reynolds GP, Zhang ZJ, Zhang XB,. 2002. Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism. Lancet 359: 2086-2087.
    • (2002) Lancet , vol.359 , pp. 2086-2087
    • Reynolds, G.P.1    Zhang, Z.J.2    Zhang, X.B.3
  • 35
    • 78649392014 scopus 로고    scopus 로고
    • Association between the 1291 -C/G polymorphism in the adrenergic α-2a receptor and the metabolic syndrome
    • Risselada AJ, Vehof J, Bruggeman R, et al,. 2010. Association between the 1291 -C/G polymorphism in the adrenergic α-2a receptor and the metabolic syndrome. J Clin Psychopharmacol 30: 667-671.
    • (2010) J Clin Psychopharmacol , vol.30 , pp. 667-671
    • Risselada, A.J.1    Vehof, J.2    Bruggeman, R.3
  • 36
    • 0036119161 scopus 로고    scopus 로고
    • A C-1291G polymorphism in the alpha2A-adrenergic receptor gene (ADRA2A) promoter is associated with cortisol escape from dexamethasone and elevated glucose levels
    • Rosmond R, Bouchard C, Bjorntorp P,. 2002. A C-1291G polymorphism in the alpha2A-adrenergic receptor gene (ADRA2A) promoter is associated with cortisol escape from dexamethasone and elevated glucose levels. J Intern Med 251: 252-257.
    • (2002) J Intern Med , vol.251 , pp. 252-257
    • Rosmond, R.1    Bouchard, C.2    Bjorntorp, P.3
  • 37
    • 54049137659 scopus 로고    scopus 로고
    • Assessment of clinical and metabolic status, and subjective well-being, in schizophrenic patients switched from typical and atypical antipsychotics to ziprasidone
    • Rossi A, Vita A, Tiradritti P, Romeo F,. 2008. Assessment of clinical and metabolic status, and subjective well-being, in schizophrenic patients switched from typical and atypical antipsychotics to ziprasidone. Int Clin Psychopharmacol 23: 216-222.
    • (2008) Int Clin Psychopharmacol , vol.23 , pp. 216-222
    • Rossi, A.1    Vita, A.2    Tiradritti, P.3    Romeo, F.4
  • 38
    • 70449510603 scopus 로고    scopus 로고
    • Association of the alpha 2A adrenergic receptor -1291C/G polymorphism and antipsychotic-induced weight gain in European-Americans
    • Sickert L, Muller DJ, Tiwari AK, et al,. 2009. Association of the alpha 2A adrenergic receptor -1291C/G polymorphism and antipsychotic-induced weight gain in European-Americans. Pharmacogenomics 10: 1169-1176.
    • (2009) Pharmacogenomics , vol.10 , pp. 1169-1176
    • Sickert, L.1    Muller, D.J.2    Tiwari, A.K.3
  • 39
    • 58849138816 scopus 로고    scopus 로고
    • Which comes first: Atypical antipsychotic treatment or cardiometabolic risk?
    • Stahl SM, Mignon L, Meyer JM,. 2009. Which comes first: atypical antipsychotic treatment or cardiometabolic risk? Acta Psychiatr Scand 119: 171-179.
    • (2009) Acta Psychiatr Scand , vol.119 , pp. 171-179
    • Stahl, S.M.1    Mignon, L.2    Meyer, J.M.3
  • 40
    • 75649110751 scopus 로고    scopus 로고
    • Changes in metabolic parameters following a switch to aripiprazole in Japanese patients with schizophrenia: One-year follow-up study
    • Takeuchi H, Uchida H, Suzuki T, Watanabe K, Kashima H, 2010. Changes in metabolic parameters following a switch to aripiprazole in Japanese patients with schizophrenia: One-year follow-up study. Psychiatry Clin Neurosci 64: 104-106.
    • (2010) Psychiatry Clin Neurosci , vol.64 , pp. 104-106
    • Takeuchi, H.1    Uchida, H.2    Suzuki, T.3    Watanabe, K.4    Kashima, H.5
  • 41
    • 17644394540 scopus 로고    scopus 로고
    • Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis
    • Templeman LA, Reynolds GP, Arranz B, San L, 2005. Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis. Pharmacogenet Genomics 15: 195-200.
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 195-200
    • Templeman, L.A.1    Reynolds, G.P.2    Arranz, B.3    San, L.4
  • 43
    • 25144477595 scopus 로고    scopus 로고
    • Polymorphism of the adrenergic receptor alpha 2a -1291C/G genetic variation and clozapine-induced weight gain
    • Wang YC, Bai YM, Chen JY, Lin CC, Lai IC, Liou YJ,. 2005. Polymorphism of the adrenergic receptor alpha 2a -1291C/G genetic variation and clozapine-induced weight gain. J Neural Transm 112: 1463-1468.
    • (2005) J Neural Transm , vol.112 , pp. 1463-1468
    • Wang, Y.C.1    Bai, Y.M.2    Chen, J.Y.3    Lin, C.C.4    Lai, I.C.5    Liou, Y.J.6
  • 44
    • 0031687887 scopus 로고    scopus 로고
    • A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity
    • Weisberg I, Tran P, Christensen B, Sibani S, Rozen R,. 1998. A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity. Mol Genet Metab 64: 169-172.
    • (1998) Mol Genet Metab , vol.64 , pp. 169-172
    • Weisberg, I.1    Tran, P.2    Christensen, B.3    Sibani, S.4    Rozen, R.5
  • 45
    • 77955471578 scopus 로고    scopus 로고
    • MTHFR genotype and differential evolution of metabolic parameters after initiation of a second generation antipsychotic: An observational study
    • van Winkel R, Moons T, Peerbooms O, et al,. 2010a. MTHFR genotype and differential evolution of metabolic parameters after initiation of a second generation antipsychotic: an observational study. Int Clin Psychopharmacol 25: 270-276.
    • (2010) Int Clin Psychopharmacol , vol.25 , pp. 270-276
    • Van Winkel, R.1    Moons, T.2    Peerbooms, O.3
  • 47
    • 34248592726 scopus 로고    scopus 로고
    • Association of clozapine-induced weight gain with a polymorphism in the leptin promoter region in patients with chronic schizophrenia in a Chinese population
    • Zhang XY, Tan YL, Zhou DF, et al,. 2007. Association of clozapine-induced weight gain with a polymorphism in the leptin promoter region in patients with chronic schizophrenia in a Chinese population. J Clin Psychopharmacol 27: 246-251.
    • (2007) J Clin Psychopharmacol , vol.27 , pp. 246-251
    • Zhang, X.Y.1    Tan, Y.L.2    Zhou, D.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.