Increased reprogramming of human fetal hepatocytes compared with adult hepatocytes in feeder-free conditions

Cell Transplantation

Volumn 23, Issue 1, 2014, Pages 27-38

  Hansel, Marc C ^a,b   Gramignoli, Roberto ^c   Blake, William ^d   Davila, Julio ^d   Skvorak, Kristen ^a   Dorko, Kenneth ^a   Tahan, Veysel ^a   Lee, Brian R ^a   Tafaleng, Edgar ^e   Guzman Lepe, Jorge ^e   Soto Gutierrez, Alejandro ^a,e   Fox, Ira J ^b,e   Strom, Stephen C ^b,c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b MCGOWAN INSTITUTE FOR REGENERATIVE MEDICINE   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

^d PFIZER INC   (United States)

^e CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

Fetal hepatocytes; Induced pluripotent stem cells (iPSCs); Metabolic liver disease; Reprogramming efficiency

Indexed keywords

CASPASE 3; CASPASE 7; DNA METHYLTRANSFERASE 3B; GROWTH DIFFERENTIATION FACTOR 3; KRUPPEL LIKE FACTOR 4; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; STAGE SPECIFIC EMBRYO ANTIGEN 3; STAGE SPECIFIC EMBRYO ANTIGEN 4; TELOMERASE REVERSE TRANSCRIPTASE; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2;

ADULT; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL COUNT; CELL CULTURE; CELL DIFFERENTIATION; CELL VIABILITY; CLINICAL ARTICLE; COLONY FORMATION; CONTROLLED STUDY; CRIGLER NAJJAR SYNDROME; CULTURE MEDIUM; CYTOTOXICITY; FEEDER FREE CONDITION; FEMALE; FETUS; FETUS CELL; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; INTESTINE EPITHELIUM; LIVER CELL; MALE; NERVOUS TISSUE; NOD SCID GAMMA MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; ONCOGENE C MYC; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TERATOMA;

ADULT; ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL GROWTH PROCESSES; CELLS, CULTURED; EMBRYONIC STEM CELLS; FEMALE; HEPATOCYTES; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INFANT; INFANT, NEWBORN; MALE; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, SCID; NUCLEAR REPROGRAMMING; YOUNG ADULT;

EID: 84892578392     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368912X662453     Document Type: Article

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