Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression, and improves muscle function in dystrophic mdx mice

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Altamirano, Francisco ^a,b   Valladares, Denisse ^a   Henríquez Olguín, Carlos ^a   Casas, Mariana ^a   López, Jose R ^b,c   Allen, Paul D ^b,c   Jaimovich, Enrique ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; APYRASE; CALCIUM; CREATINE KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NIFEDIPINE; PROTEIN BAX; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DUCHENNE MUSCULAR DYSTROPHY; FLEXOR DIGITORUM BREVIS MUSCLE; GENE; GENE EXPRESSION; IN VIVO STUDY; MALE; MDX GENE; MOUSE; MUSCLE FUNCTION; MUSCLE STRENGTH; MYOTUBE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; SKELETAL MUSCLE; VASTUS LATERALIS MUSCLE;

ANIMALS; CALCIUM; CELLS, CULTURED; CREATINE KINASE; MALE; MICE; MICE, INBRED MDX; MUSCLE STRENGTH; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, DUCHENNE; NF-KAPPA B; NIFEDIPINE; NITRIC OXIDE SYNTHASE TYPE II;

EID: 84892576727     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081222     Document Type: Article

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