Polyphosphate-mediated inhibition of tartrate-resistant acid phosphatase and suppression of bone resorption of osteoclasts

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Harada, Kana ^a   Itoh, Hiromichi ^b   Kawazoe, Yumi ^b   Miyazaki, Shuichi ^c   Doi, Kazuya ^a   Kubo, Takayasu ^a   Akagawa, Yasumasa ^a   Shiba, Toshikazu ^b,d  

^a HIROSHIMA UNIVERSITY   (Japan)

^b Regenetiss Inc   (Japan)

^c YAMASA CORPORATION   (Japan)

^d KITASATO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2,2' BIPYRIDINE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; COLONY STIMULATING FACTOR 1; OSTEOCLAST DIFFERENTIATION FACTOR; PHOSPHATASE; PHOSPHATE; POLYPHOSPHATE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; DEGRADATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; RAT;

2,2'-DIPYRIDYL; ACID PHOSPHATASE; ANIMALS; ANTIBODIES, MONOCLONAL; BONE AND BONES; BONE RESORPTION; CELL DIFFERENTIATION; IMMUNOPRECIPITATION; IRON CHELATING AGENTS; ISOENZYMES; MACROPHAGE COLONY-STIMULATING FACTOR; OSTEOCLASTS; OSTEOGENESIS; POLYPHOSPHATES; PRIMARY CELL CULTURE; RANK LIGAND; RATS; REACTIVE OXYGEN SPECIES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 84892569895     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078612     Document Type: Article

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