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Volumn 27, Issue , 2014, Pages 1-12

VEGF and BMP-2 promote bone regeneration by facilitating bone marrow stem cell homing and differentiation

Author keywords

BMP 2; Bone regeneration; Cell homing; Silk fibroin; Stem cells; VEGF

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; GREEN FLUORESCENT PROTEIN; STAGE SPECIFIC EMBRYO ANTIGEN 4; TISSUE SCAFFOLD; VASCULOTROPIN;

EID: 84892563631     PISSN: 14732262     EISSN: None     Source Type: Journal    
DOI: 10.22203/eCM.v027a01     Document Type: Article
Times cited : (167)

References (47)
  • 2
    • 0033565540 scopus 로고    scopus 로고
    • VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells
    • Asahara T, Takahashi T, Masuda H, Kalka C, Chen D, Iwaguro H, Inai Y, Silver M, Isner JM (1999) VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J 18: 3964-3972.
    • (1999) EMBO J , vol.18 , pp. 3964-3972
    • Asahara, T.1    Takahashi, T.2    Masuda, H.3    Kalka, C.4    Chen, D.5    Iwaguro, H.6    Inai, Y.7    Silver, M.8    Isner, J.M.9
  • 3
    • 79952172937 scopus 로고    scopus 로고
    • Locally applied vascular endothelial growth factor A increases the osteogenic healing capacity of human adipose-derived stem cells by promoting osteogenic and endothelial differentiation
    • Behr B, Tang C, Germann G, Longaker MT, Quarto N (2011) Locally applied vascular endothelial growth factor A increases the osteogenic healing capacity of human adipose-derived stem cells by promoting osteogenic and endothelial differentiation. Stem Cells 29: 286-296.
    • (2011) Stem Cells , vol.29 , pp. 286-296
    • Behr, B.1    Tang, C.2    Germann, G.3    Longaker, M.T.4    Quarto, N.5
  • 4
    • 79951740978 scopus 로고    scopus 로고
    • Homing of endogenous stem/progenitor cells for in situ tissue regeneration: Promises, strategies, and translational perspectives
    • Chen FM, Wu LA, Zhang M, Zhang R, Sun HH (2011) Homing of endogenous stem/progenitor cells for in situ tissue regeneration: Promises, strategies, and translational perspectives. Biomaterials 32: 3189-3209.
    • (2011) Biomaterials , vol.32 , pp. 3189-3209
    • Chen, F.M.1    Wu, L.A.2    Zhang, M.3    Zhang, R.4    Sun, H.H.5
  • 5
    • 26444469934 scopus 로고    scopus 로고
    • Repair of alveolar clefts with recombinant human bone morphogenetic protein (rhBMP-2) in patients with clefts
    • Chin M, Ng T, Tom WK, Carstens M (2005) Repair of alveolar clefts with recombinant human bone morphogenetic protein (rhBMP-2) in patients with clefts. J Craniofac Surg 16: 778-789.
    • (2005) J Craniofac Surg , vol.16 , pp. 778-789
    • Chin, M.1    Ng, T.2    Tom, W.K.3    Carstens, M.4
  • 7
    • 67649920749 scopus 로고    scopus 로고
    • Growth factors, matrices, and forces combine and control stem cells
    • Discher DE, Mooney DJ, Zandstra PW (2009) Growth factors, matrices, and forces combine and control stem cells. Science 324: 1673-1677.
    • (2009) Science , vol.324 , pp. 1673-1677
    • Discher, D.E.1    Mooney, D.J.2    Zandstra, P.W.3
  • 10
    • 0042704757 scopus 로고    scopus 로고
    • Extracellular matrix-bound vascular endothelial growth factor promotes endothelial cell adhesion, migration, and survival through integrin ligation
    • Hutchings H, Ortega N, Plouët J (2003) Extracellular matrix-bound vascular endothelial growth factor promotes endothelial cell adhesion, migration, and survival through integrin ligation. FASEB J 17: 1520-1522.
    • (2003) FASEB J , vol.17 , pp. 1520-1522
    • Hutchings, H.1    Ortega, N.2    Plouët, J.3
  • 11
    • 79953676012 scopus 로고    scopus 로고
    • Tendon tissue engineering: Adipose-derived stem cell and GDF-5 mediated regeneration using electrospun matrix systems
    • James R, Kumbar S, Laurencin C, Balian G, Chhabra A (2011) Tendon tissue engineering: adipose-derived stem cell and GDF-5 mediated regeneration using electrospun matrix systems. Biomed Mater 6: 025011.
    • (2011) Biomed Mater , vol.6 , pp. 025011
    • James, R.1    Kumbar, S.2    Laurencin, C.3    Balian, G.4    Chhabra, A.5
  • 12
    • 84861702067 scopus 로고    scopus 로고
    • On novel options for oromaxillofacial functional restoration
    • Jiang X (2012) On novel options for oromaxillofacial functional restoration. Int J Prosthodont 25: 132-134.
    • (2012) Int J Prosthodont , vol.25 , pp. 132-134
    • Jiang, X.1
  • 13
    • 70449427755 scopus 로고    scopus 로고
    • Maxillary sinus floor elevation using a tissue-engineered bone complex with beta-TCP and BMP-2 gene-modified bMSCs in rabbits
    • Jiang XQ, Sun XJ, Lai HC, Zhao J, Wang SY, Zhang ZY (2009) Maxillary sinus floor elevation using a tissue-engineered bone complex with beta-TCP and BMP-2 gene-modified bMSCs in rabbits. Clin Oral Implants Res 20: 1333-1340.
    • (2009) Clin Oral Implants Res , vol.20 , pp. 1333-1340
    • Jiang, X.Q.1    Sun, X.J.2    Lai, H.C.3    Zhao, J.4    Wang, S.Y.5    Zhang, Z.Y.6
  • 14
    • 77956637468 scopus 로고    scopus 로고
    • Sequential fluorescent labeling observation of maxillary sinus augmentation by a tissue-engineered bone complex in canine model
    • Jiang XQ, Wang SY, Zhao J, Zhang XL, Zhang ZY (2009) Sequential fluorescent labeling observation of maxillary sinus augmentation by a tissue-engineered bone complex in canine model. Int J Oral Sci 1: 39-46.
    • (2009) Int J Oral Sci , vol.1 , pp. 39-46
    • Jiang, X.Q.1    Wang, S.Y.2    Zhao, J.3    Zhang, X.L.4    Zhang, Z.Y.5
  • 15
    • 45549085001 scopus 로고    scopus 로고
    • Osteogenesis and angiogenesis: The potential for engineering bone
    • Kanczler JM, Oreffo RO (2008) Osteogenesis and angiogenesis: the potential for engineering bone. Eur Cell Mater 15: 100-114.
    • (2008) Eur Cell Mater , vol.15 , pp. 100-114
    • Kanczler, J.M.1    Oreffo, R.O.2
  • 16
    • 72449179318 scopus 로고    scopus 로고
    • The effect of the delivery of vascular endothelial growth factor and bone morphogenic protein-2 to osteoprogenitor cell populations on bone formation
    • Kanczler JM, Ginty PJ, White L, Clarke NM, Howdle SM, Shakesheff KM, Oreffo RO (2010) The effect of the delivery of vascular endothelial growth factor and bone morphogenic protein-2 to osteoprogenitor cell populations on bone formation. Biomaterials 31: 1242-1250.
    • (2010) Biomaterials , vol.31 , pp. 1242-1250
    • Kanczler, J.M.1    Ginty, P.J.2    White, L.3    Clarke, N.M.4    Howdle, S.M.5    Shakesheff, K.M.6    Oreffo, R.O.7
  • 19
    • 0031985282 scopus 로고    scopus 로고
    • In vitro behavior of hematopoietic progenitor cells under the influence of chemoattractants: Stromal cell-derived factor-1, steel factor, and the bone marrow environment
    • Kim CH, Broxmeyer HE (1998) In vitro behavior of hematopoietic progenitor cells under the influence of chemoattractants: stromal cell-derived factor-1, steel factor, and the bone marrow environment. Blood 91: 100-110.
    • (1998) Blood , vol.91 , pp. 100-110
    • Kim, C.H.1    Broxmeyer, H.E.2
  • 20
    • 77955481932 scopus 로고    scopus 로고
    • Anatomically shaped tooth and periodontal regeneration by cell homing
    • Kim K, Lee C, Kim B, Mao J (2010) Anatomically shaped tooth and periodontal regeneration by cell homing. J Dent Res 89: 842-847.
    • (2010) J Dent Res , vol.89 , pp. 842-847
    • Kim, K.1    Lee, C.2    Kim, B.3    Mao, J.4
  • 22
    • 3543145020 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 stimulates angiogenesis in developing tumors
    • Langenfeld EM, Langenfeld J (2004) Bone morphogenetic protein-2 stimulates angiogenesis in developing tumors. Mol Cancer Res 2: 141-149.
    • (2004) Mol Cancer Res , vol.2 , pp. 141-149
    • Langenfeld, E.M.1    Langenfeld, J.2
  • 23
    • 41949103629 scopus 로고    scopus 로고
    • Mobilization of endothelial progenitor cells in fracture healing and distraction osteogenesis
    • Lee DY, Cho TJ, Kim JA, Lee HR, Yoo WJ, Chung CY, Choi IH (2008) Mobilization of endothelial progenitor cells in fracture healing and distraction osteogenesis. Bone 42: 932-941.
    • (2008) Bone , vol.42 , pp. 932-941
    • Lee, D.Y.1    Cho, T.J.2    Kim, J.A.3    Lee, H.R.4    Yoo, W.J.5    Chung, C.Y.6    Choi, I.H.7
  • 24
    • 77955565285 scopus 로고    scopus 로고
    • Regeneration of the articular surface of the rabbit synovial joint by cell homing: A proof of concept study
    • Lee CH, Cook JL, Mendelson A, Moioli EK, Yao H, Mao JJ (2010) Regeneration of the articular surface of the rabbit synovial joint by cell homing: a proof of concept study. Lancet 376: 440-448.
    • (2010) Lancet , vol.376 , pp. 440-448
    • Lee, C.H.1    Cook, J.L.2    Mendelson, A.3    Moioli, E.K.4    Yao, H.5    Mao, J.J.6
  • 25
    • 78650842405 scopus 로고    scopus 로고
    • Growth factor delivery-based tissue engineering: General approaches and a review of recent developments
    • Lee K, Silva EA, Mooney DJ (2011) Growth factor delivery-based tissue engineering: general approaches and a review of recent developments. J R Soc Interface 8: 153-170.
    • (2011) J R Soc Interface , vol.8 , pp. 153-170
    • Lee, K.1    Silva, E.A.2    Mooney, D.J.3
  • 28
    • 76749091376 scopus 로고    scopus 로고
    • The healing of critical-sized femoral segmental bone defects in rabbits using baculovirus-engineered mesenchymal stem cells
    • Lin CY, Chang YH, Lin KJ, Yen TC, Tai CL, Chen CY, Lo WH, Hsiao IT, Hu YC (2010) The healing of critical-sized femoral segmental bone defects in rabbits using baculovirus-engineered mesenchymal stem cells. Biomaterials 31: 3222-3230.
    • (2010) Biomaterials , vol.31 , pp. 3222-3230
    • Lin, C.Y.1    Chang, Y.H.2    Lin, K.J.3    Yen, T.C.4    Tai, C.L.5    Chen, C.Y.6    Lo, W.H.7    Hsiao, I.T.8    Hu, Y.C.9
  • 29
    • 0030049816 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 but not bone morphogenetic protein-4 and-6 stimulates chemotactic migration of human osteoblasts, human marrow osteoblasts, and U2-OS cells
    • Lind M, Eriksen EF, Bünger C (1996) Bone morphogenetic protein-2 but not bone morphogenetic protein-4 and-6 stimulates chemotactic migration of human osteoblasts, human marrow osteoblasts, and U2-OS cells. Bone 18: 53-57.
    • (1996) Bone , vol.18 , pp. 53-57
    • Lind, M.1    Eriksen, E.F.2    Bünger, C.3
  • 30
    • 69649083312 scopus 로고    scopus 로고
    • Segmental bone regeneration using an rhBMP-2-loaded gelatin/nanohydroxyapatite/fibrin scaffold in a rabbit model
    • Liu Y, Lu Y, Tian X, Cui G, Zhao Y, Yang Q, Yu S, Xing G, Zhang B (2009) Segmental bone regeneration using an rhBMP-2-loaded gelatin/nanohydroxyapatite/fibrin scaffold in a rabbit model. Biomaterials 30: 6276-6285.
    • (2009) Biomaterials , vol.30 , pp. 6276-6285
    • Liu, Y.1    Lu, Y.2    Tian, X.3    Cui, G.4    Zhao, Y.5    Yang, Q.6    Yu, S.7    Xing, G.8    Zhang, B.9
  • 31
    • 2542588554 scopus 로고    scopus 로고
    • Porous 3-D scaffolds from regenerated silk fibroin
    • Nazarov R, Jin HJ, Kaplan DL (2004) Porous 3-D scaffolds from regenerated silk fibroin. Biomacromolecules 5: 718-726.
    • (2004) Biomacromolecules , vol.5 , pp. 718-726
    • Nazarov, R.1    Jin, H.J.2    Kaplan, D.L.3
  • 32
    • 77955896694 scopus 로고    scopus 로고
    • Effects of platelet-rich plasma and chitosan combination on bone regeneration in experimental rabbit cranial defects
    • Oktay EO, Demiralp B, Senel S, Cevdet Akman A, Eratalay K, Akincibay H (2010) Effects of platelet-rich plasma and chitosan combination on bone regeneration in experimental rabbit cranial defects. J Oral Implantol 36: 175-184.
    • (2010) J Oral Implantol , vol.36 , pp. 175-184
    • Oktay, E.O.1    Demiralp, B.2    Senel, S.3    Cevdet Akman, A.4    Eratalay, K.5    Akincibay, H.6
  • 33
    • 77955111796 scopus 로고    scopus 로고
    • New opportunities for an ancient material
    • Omenetto FG, Kaplan DL (2010) New opportunities for an ancient material. Science 329: 528-531.
    • (2010) Science , vol.329 , pp. 528-531
    • Omenetto, F.G.1    Kaplan, D.L.2
  • 34
    • 27444446737 scopus 로고    scopus 로고
    • VEGF improves, whereas sFlt1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis
    • Peng H, Usas A, Olshanski A, Ho AM, Gearhart B, Cooper GM, Huard J (2005) VEGF improves, whereas sFlt1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis. J Bone Miner Res 20: 2017-2027.
    • (2005) J Bone Miner Res , vol.20 , pp. 2017-2027
    • Peng, H.1    Usas, A.2    Olshanski, A.3    Ho, A.M.4    Gearhart, B.5    Cooper, G.M.6    Huard, J.7
  • 35
    • 34347388823 scopus 로고    scopus 로고
    • Role of bone morphogenetic protein 2 in the crosstalk between endothelial progenitor cells and mesenchymal stem cells
    • Raida M, Heymann A, Günther C, Niederwieser D (2006) Role of bone morphogenetic protein 2 in the crosstalk between endothelial progenitor cells and mesenchymal stem cells. Int J Mol Med 18: 735-739.
    • (2006) Int J Mol Med , vol.18 , pp. 735-739
    • Raida, M.1    Heymann, A.2    Günther, C.3    Niederwieser, D.4
  • 36
    • 38949183635 scopus 로고    scopus 로고
    • Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone
    • Sackstein R, Merzaban JS, Cain DW, Dagia NM, Spencer JA, Lin CP, Wohlgemuth R (2008) Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone. Nat Med 14: 181-187.
    • (2008) Nat Med , vol.14 , pp. 181-187
    • Sackstein, R.1    Merzaban, J.S.2    Cain, D.W.3    Dagia, N.M.4    Spencer, J.A.5    Lin, C.P.6    Wohlgemuth, R.7
  • 37
    • 52949105668 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 (BMP-2) and vascular endothelial growth factor (VEGF) transfection to human periosteal cells enhances osteoblast differentiation and bone formation
    • Samee M, Kasugai S, Kondo H, Ohya K, Shimokawa H, Kuroda S (2008) Bone morphogenetic protein-2 (BMP-2) and vascular endothelial growth factor (VEGF) transfection to human periosteal cells enhances osteoblast differentiation and bone formation. J Pharmacol Sci 108: 18-31.
    • (2008) J Pharmacol Sci , vol.108 , pp. 18-31
    • Samee, M.1    Kasugai, S.2    Kondo, H.3    Ohya, K.4    Shimokawa, H.5    Kuroda, S.6
  • 38
    • 84863230530 scopus 로고    scopus 로고
    • Gene therapy with growth factors for periodontal tissue engineering--a review
    • Sood S, Gupta S, Mahendra A (2012) Gene therapy with growth factors for periodontal tissue engineering--a review. Med Oral Patol Oral Cir Bucal 17: e301-310.
    • (2012) Med Oral Patol Oral Cir Bucal , vol.17
    • Sood, S.1    Gupta, S.2    Mahendra, A.3
  • 39
    • 77649275535 scopus 로고    scopus 로고
    • The effect of incorporation of SDF-1α into PLGA scaffolds on stem cell recruitment and the inflammatory response
    • Thevenot PT, Nair AM, Shen J, Lotfi P, Ko C-Y, Tang L (2010) The effect of incorporation of SDF-1α into PLGA scaffolds on stem cell recruitment and the inflammatory response. Biomaterials 31: 3997-4008.
    • (2010) Biomaterials , vol.31 , pp. 3997-4008
    • Thevenot, P.T.1    Nair, A.M.2    Shen, J.3    Lotfi, P.4    Ko, C.-Y.5    Tang, L.6
  • 41
    • 80052153717 scopus 로고    scopus 로고
    • Mending the youngest hearts
    • Vogel G (2011) Mending the youngest hearts. Science 333: 1088-1089.
    • (2011) Science , vol.333 , pp. 1088-1089
    • Vogel, G.1
  • 42
    • 61349146180 scopus 로고    scopus 로고
    • Vertical alveolar ridge augmentation with beta-tricalcium phosphate and autologous osteoblasts in canine mandible
    • Wang S, Zhang Z, Zhao J, Zhang X, Sun X, Xia L, Chang Q, Ye D, Jiang X (2009) Vertical alveolar ridge augmentation with beta-tricalcium phosphate and autologous osteoblasts in canine mandible. Biomaterials 30: 2489-2498.
    • (2009) Biomaterials , vol.30 , pp. 2489-2498
    • Wang, S.1    Zhang, Z.2    Zhao, J.3    Zhang, X.4    Sun, X.5    Xia, L.6    Chang, Q.7    Ye, D.8    Jiang, X.9
  • 44
    • 80053607677 scopus 로고    scopus 로고
    • The use of injectable sonication-induced silk hydrogel for VEGF165 and BMP-2 delivery for elevation of the maxillary sinus floor
    • Zhang W, Wang X, Wang S, Zhao J, Xu L, Zhu C, Zeng D, Chen J, Zhang Z, Kaplan DL, Jiang X (2011) The use of injectable sonication-induced silk hydrogel for VEGF165 and BMP-2 delivery for elevation of the maxillary sinus floor. Biomaterials 32: 9415-9424.
    • (2011) Biomaterials , vol.32 , pp. 9415-9424
    • Zhang, W.1    Wang, X.2    Wang, S.3    Zhao, J.4    Xu, L.5    Zhu, C.6    Zeng, D.7    Chen, J.8    Zhang, Z.9    Kaplan, D.L.10    Jiang, X.11
  • 45
    • 80051698478 scopus 로고    scopus 로고
    • LvBMP-2 gene-modified BMSCs combined with calcium phosphate cement scaffolds for the repair of calvarial defects in rats
    • Zhu C, Chang Q, Zou D, Zhang W, Wang S, Zhao J, Yu W, Zhang X, Zhang Z, Jiang X (2011) LvBMP-2 gene-modified BMSCs combined with calcium phosphate cement scaffolds for the repair of calvarial defects in rats. J Mater Sci Mater Med 22: 1965-1973.
    • (2011) J Mater Sci Mater Med , vol.22 , pp. 1965-1973
    • Zhu, C.1    Chang, Q.2    Zou, D.3    Zhang, W.4    Wang, S.5    Zhao, J.6    Yu, W.7    Zhang, X.8    Zhang, Z.9    Jiang, X.10
  • 46


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