let-7-repressesed Shc translation delays replicative senescence

Aging Cell

Volumn 13, Issue 1, 2014, Pages 185-192

  Xu, Fang ^a   Pang, Lijun ^a   Cai, Xiaoyu ^a   Liu, Xinwen ^a   Yuan, Shuai ^a   Fan, Xiuqin ^a   Jiang, Bin ^a   Zhang, Xiaowei ^a   Dou, Yali ^b   Gorospe, Myriam ^c   Wang, Wengong ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b UNIVERSITY OF MICHIGAN   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Cellular lifespan; Let 7a; P66Shc; Replicative senescence; Translational regulation

Indexed keywords

MESSENGER RNA; MICRORNA; MICRORNA 22; MICRORNA 30; MICRORNA 9; PROTEIN LET 7A; PROTEIN P46; PROTEIN P52; PROTEIN P66; PROTEIN SHC; UNCLASSIFIED DRUG; MIRNLET7 MICRORNA, HUMAN; PROTEIN BINDING; SHC1 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ARTICLE; CELL AGING; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL SURVIVAL; DIPLOIDY; FIBROBLAST; GENE MUTATION; GENE REPRESSION; GENETIC CODE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RNA PROCESSING; BIOSYNTHESIS; GENETICS; METABOLISM; OPEN READING FRAME; PROTEIN SYNTHESIS; REGULATORY SEQUENCE;

MAMMALIA;

CELL AGING; DIPLOIDY; FIBROBLASTS; HUMANS; MICRORNAS; OPEN READING FRAMES; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; REGULATORY SEQUENCES, NUCLEIC ACID; RNA, MESSENGER; SHC SIGNALING ADAPTOR PROTEINS;

EID: 84892560929     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12176     Document Type: Article

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