Catechol-O-methyltransferase Val158Met polymorphism and altered COMT gene expression in the prefrontal cortex of suicide brains

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 50, Issue , 2014, Pages 178-183

  Du, Lisheng ^a   Merali, Zul ^a   Poulter, Michael O ^b   Palkovits, Miklós ^c   Faludi, Gábor ^d   Anisman, Hymie ^e  

^a UNIVERSITY OF OTTAWA   (Canada)

^b ROBARTS RESEARCH INSTITUTE   (Canada)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^d SEMMELWEIS UNIVERSITY   (Hungary)

^e CARLETON UNIVERSITY   (Canada)

Author keywords

COMT polymorphism; Depression; MRNA expression; Prefrontal cortex; Suicide

Indexed keywords

CATECHOL METHYLTRANSFERASE; MESSENGER RNA; METHIONINE; VALINE;

ADULT; AGED; ARTICLE; CATECHOLAMINERGIC SYSTEM; CAUSE OF DEATH; CLINICAL ARTICLE; COMT GENE; CONTROLLED STUDY; DEPRESSION; DNA POLYMORPHISM; FEMALE; FRONTAL CORTEX; GENE EXPRESSION; GENE FREQUENCY; GENOTYPE; HETEROZYGOTE; HUMAN; HUMAN TISSUE; MALE; MIDDLE AGED; ORBITAL CORTEX; PATHOPHYSIOLOGY; PREFRONTAL CORTEX; SUICIDAL BEHAVIOR; UPREGULATION; VICTIM; BIOSYNTHESIS; CASE CONTROL STUDY; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETICS; METABOLISM; SINGLE NUCLEOTIDE POLYMORPHISM; SUICIDE;

AGED; CASE-CONTROL STUDIES; CATECHOL O-METHYLTRANSFERASE; DEPRESSION; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PREFRONTAL CORTEX; SUICIDE; UP-REGULATION;

EID: 84892541716     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2013.12.016     Document Type: Article

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