Collagenase-resistant collagen promotes mouse aging and vascular cell senescence

Aging Cell

Volumn 13, Issue 1, 2014, Pages 121-130

  Vafaie, Faran ^a,b   Yin, Hao ^a   O'Neil, Caroline ^a   Nong, Zengxuan ^a   Watson, Alanna ^a,b   Arpino, John Michael ^a,b   Chu, Michael W A ^b,c   Wayne Holdsworth, David ^a,b   Gros, Robert ^a,b   Pickering, J Geoffrey ^a,b,c  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c LONDON HEALTH SCIENCES CENTRE   (Canada)

Author keywords

Collagen; Integrin; Senescence; Vascular smooth muscle

Indexed keywords

ALPHAVBETA3 BLOCKING ANTIBODY; ANGIOTENSIN II; BETA GALACTOSIDASE; BLOCKING ANTIBODY; COLLAGEN TYPE 1; COLLAGENASE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; ECHISTATIN; SENESCENCE ASSOCIATED BETA GALACTOSIDASE; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR; COLLAGEN TYPE I, ALPHA 1 CHAIN;

ANIMAL CELL; ANIMAL TISSUE; AORTA WALL; ARTICLE; BONE DENSITY; CELL AGING; CELL COMPARTMENTALIZATION; CELL SURVIVAL; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; CORONARY ARTERY BYPASS SURGERY; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HYPERTENSION; KYPHOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SENESCENCE; UPREGULATION; VASCULAR SMOOTH MUSCLE; WEIGHT REDUCTION; WILD TYPE; AGING; ANIMAL; ANIMAL EMBRYO; AORTA; C57BL MOUSE; CYTOLOGY; DRUG EFFECTS; FIBROBLAST; LONGEVITY; METABOLISM; PATHOLOGY; PHENOTYPE; PHYSIOLOGICAL STRESS; SMOOTH MUSCLE FIBER;

MAMMALIA; MUS;

AGING; ANGIOTENSIN II; ANIMALS; AORTA; CELL AGING; COLLAGEN TYPE I; COLLAGENASES; EMBRYO, MAMMALIAN; FIBROBLASTS; HUMANS; HYPERTENSION; INTEGRIN ALPHAVBETA3; LONGEVITY; MICE; MICE, INBRED C57BL; MYOCYTES, SMOOTH MUSCLE; PHENOTYPE; PROTEOLYSIS; STRESS, PHYSIOLOGICAL;

EID: 84892509852     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12155     Document Type: Article

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