Hydroalcoholic extract of Rhodiola rosea L. (Crassulaceae) and its hydrolysate inhibit melanogenesis in B16F0 cells by regulating the CREB/MITF/tyrosinase pathway

Food and Chemical Toxicology

Volumn 65, Issue , 2014, Pages 129-139

  Chiang, Hsiu Mei ^a   Chien, Yin Chih ^a   Wu, Chieh Hsi ^a   Kuo, Yueh Hsiung ^a,b   Wu, Wan Chen ^a   Pan, Yu Yun ^a   Su, Yu Han ^a   Wen, Kuo Ching ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b ASIA UNIVERSITY   (Taiwan)

Author keywords

CREB; GSK3 ; MC1R; Melanin; Rhodiola rosea; Tyrosinase

Indexed keywords

ALCOHOL; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; MELANIN; MELANOCORTIN 1 RECEPTOR; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MONOPHENOL MONOOXYGENASE; PROTEIN HYDROLYSATE; PROTEIN KINASE B; RHODIOLA ROSEA EXTRACT; SALIDROSIDE; TYROSINASE RELATED PROTEIN 1; TYROSOL;

ANIMAL CELL; ANTI MELANOGENIC EFFECT; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; ENZYME REPRESSION; ENZYME SYNTHESIS; GENE EXPRESSION; IN VIVO STUDY; MELANOGENESIS; MOUSE; NONHUMAN; PLANT ROOT; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN HYDROLYSIS; SIGNAL TRANSDUCTION;

CREB; GSK3Β; MC1R; MELANIN; RHODIOLA ROSEA; TYROSINASE;

ANIMALS; CELL LINE, TUMOR; CRASSULACEAE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; HYDROLYSIS; MELANINS; MELANOMA, EXPERIMENTAL; MICE; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; MONOPHENOL MONOOXYGENASE; PLANT EXTRACTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84892493577     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.12.032     Document Type: Article

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