Early biomarkers identified in a rat model of a healthier phenotype based on early postnatal dietary intervention may predict the response to an obesogenic environment in adulthood

Journal of Nutritional Biochemistry

Volumn 25, Issue 2, 2014, Pages 208-218

  Torrens, Juana M ^a   Konieczna, Jadwiga ^a   Palou, Mariona ^a   Sánchez, Juana ^a   Picó, Catalina ^a   Palou, Andreu ^a  

^a UNIVERSITAT DE LES ILLES BALEARS   (Spain)

Author keywords

Adipose tissue; Calorie restriction; Early markers; Lactation; Liver; Obesity

Indexed keywords

ADIPONECTIN; BIOLOGICAL MARKER; CARNITINE PALMITOYLTRANSFERASE I; FATTY ACID; GLUCOSE; INSULIN; LEPTIN; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL;

ADULT; ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALORIC RESTRICTION; CONTROLLED STUDY; EARLY INTERVENTION; ENERGY BALANCE; FEMALE; GENE EXPRESSION; LIPID DIET; LIPID LIVER LEVEL; LIPOGENESIS; LIPOLYSIS; MALE; NONHUMAN; OBESITY; PHENOTYPE; RAT; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE; CALORIE RESTRICTION; EARLY MARKERS; LACTATION; LIVER; OBESITY;

ANIMALS; BIOLOGICAL MARKERS; FEEDING BEHAVIOR; FEMALE; LIPID METABOLISM; LIVER; MALE; MODELS, BIOLOGICAL; OBESITY; PHENOTYPE; RATS; RNA, MESSENGER;

EID: 84892490124     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2013.10.009     Document Type: Article

References (34)

1. Taylor P., Poston L. Developmental programming of obesity in mammals. Exp Physiol 2007, 92:287-298.
2. McMillen I., MacLaughlin S., Muhlhausler B., et al. Developmental origins of adult health and disease: the role of periconceptional and foetal nutrition. Basic Clin Pharmacol Toxicol 2008, 102:82-89.
3. Picó C., Palou M., Priego T., et al. Metabolic programming of obesity by energy restriction during the perinatal period: different outcomes depending on gender and period, type and severity of restriction. Front Physiol 2012, 3:436.
4. McMillen I.C., Adam C.L., Mühlhäusler B.S. Early origins of obesity: programming the appetite regulatory system. J Physiol 2005, 565:9-17.
5. de Moura E.G., Lisboa P.C., Custódio C.M., et al. Malnutrition during lactation changes growth hormone mRNA expression in offspring at weaning and in adulthood. J Nutr Biochem 2007, 18:134-139.
6. Fagundes A.T., Moura E.G., Passos M.C., et al. Maternal low-protein diet during lactation programmes body composition and glucose homeostasis in the adult rat offspring. Br J Nutr 2007, 98:922-928.
7. Palou M., Priego T., Sánchez J., et al. Moderate caloric restriction in lactating rats protects offspring against obesity and insulin resistance in later life. Endocrinology 2010, 15:1030-1041.
8. Palou M., Konieczna J., Torrens J.M., et al. Impaired insulin and leptin sensitivity in the offspring of moderate caloric-restricted dams during gestation is early programmed. J Nutr Biochem 2012, 23:1627-1639.
9. Dewey K.G. Maternal body composition, caloric restriction and exercise during lactation: an overview. J Nutr 1998, 128.
10. Dusdieker L.B., Hemingway D.L., Stumbo P.J. Is milk production impaired by dieting during lactation?. Am J Clin Nutr 1994, 59:833-840.
11. Roberts S.B., Cole T.J., Coward W.A. Lactational performance in relation to energy intake in the baboon. Am J Clin Nutr 1985, 4:1270-1276.
12. Matthews D.R., Hosker J.P., Rudenski A.S., et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28:412-419.
13. Folch J., Lees M., Sloane Stanley G.H. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 1957, 226:497-509.
14. Priego T., Sánchez J., Picó C., et al. Sex-differential expression of metabolism-related genes in response to a high-fat diet. Obesity (Silver Spring) 2008, 16:819-826.
15. Palou M., Priego T., Sánchez J., et al. Gene expression patterns in visceral and subcutaneous adipose depots in rats are linked to their morphologic features. Cell Physiol Biochem 2009, 24:547-556.
16. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408.
17. Palou M., Sánchez J., Priego T., et al. Regional differences in the expression of genes involved in lipid metabolism in adipose tissue in response to short- and medium-term fasting and refeeding. J Nutr Biochem 2010, 21:23-33.
18. Palou M., Torrens J.M., Priego T., et al. Moderate caloric restriction in lactating rats programs their offspring for a better response to HF diet feeding in a sex-dependent manner. J Nutr Biochem 2011, 22:574-584.
19. Remmers F., Fodor M., de Waal HA Delemarre-van Neonatal food restriction permanently alters rat body dimensions and energy intake. Physiol Behav 2008, 95:208-215.
20. Remmers F., Schreuder M.F., Gemke R.J., et al. Energy intake and resting energy expenditure in adult male rats after early postnatal food restriction. Br J Nutr 2008, 9:1149-1156.
21. Friedman J.M., Halaas J.L. Leptin and the regulation of body weight in mammals. Nature 1998, 395:763-770.
22. Berg A.H., Combs T.P., Du X., et al. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 2001, 7:947-953.
23. Yamauchi T., Kamon J., Waki H., et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001, 7:941-946.
24. Finucane F.M., Luan J., Wareham N.J., et al. Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals. Diabetologia 2009, 52:2345-2349.
25. Satoh N., Naruse M., Usui T., et al. Leptin-to-adiponectin ratio as a potential atherogenic index in obese type 2 diabetic patients. Diabetes Care 2004, 27:2488-2490.
26. Ansar S., Koska J., Reaven P.D. Postprandial hyperlipidemia, endothelial dysfunction and cardiovascular risk: focus on incretins. Cardiovasc Diabetol 2011, 10:61.
27. Postic C., Girard J. Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice. J Clin Invest 2008, 118:829-838.
28. Brock R.W., Dorman R.B. Obesity, insulin resistance and hepatic perfusion. Microcirculation 2007, 14:339-347.
29. Guo K., McMinn J.E., Ludwig T., et al. Disruption of peripheral leptin signaling in mice results in hyperleptinemia without associated metabolic abnormalities. Endocrinology 2007, 148:3987-3997.
30. Brabant G., Müller G., Horn R., et al. Hepatic leptin signaling in obesity. FASEB J 2005, 19:1048-1050.
31. Browning J.D., Horton J.D. Molecular mediators of hepatic steatosis and liver injury. J Clin Invest 2004, 114:147-152.
32. Wendel A.A., Lewin T.M., Coleman R.A. Glycerol-3-phosphate acyltransferases: rate limiting enzymes of triacylglycerol biosynthesis. Biochim Biophys Acta 2009, 1791:501-506.
33. Turpin S.M., Hoy A.J., Brown R.D., et al. Adipose triacylglycerol lipase is a major regulator of hepatic lipid metabolism but not insulin sensitivity in mice. Diabetologia 2011, 54:146-156.
34. Orellana-Gavaldà J.M., Herrero L., Malandrino M.I., et al. Molecular therapy for obesity and diabetes based on a long-term increase in hepatic fatty-acid oxidation. Hepatology 2011, 53:821-832.