The Vps35 D620N Mutation Linked to Parkinson's Disease Disrupts the Cargo Sorting Function of Retromer

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Volumn 15, Issue 2, 2014, Pages 230-244

  Follett, Jordan ^a   Norwood, Suzanne J ^a   Hamilton, Nicholas A ^a   Mohan, Megha ^b   Kovtun, Oleksiy ^a   Tay, Stephanie ^a   Zhe, Yang ^a   Wood, Stephen A ^b   Mellick, George D ^b   Silburn, Peter A ^b,c   Collins, Brett M ^a   Bugarcic, Andrea ^a   Teasdale, Rohan D ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b GRIFFITH UNIVERSITY   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Cathepsin D; Endosome; Parkinson's disease; Retromer; Vps35 D620N

Indexed keywords

CATHEPSIN D; CATION INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR; CELL PROTEIN; MULTIPROTEIN COMPLEX; RETROMER; SOMATOMEDIN B RECEPTOR; UNCLASSIFIED DRUG; VPS26A PROTEIN; VPS29 PROTEIN; VPS35 D620N PROTEIN; VPS35 PROTEIN;

ARTICLE; BINDING AFFINITY; CARGO SORTING; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE ASSOCIATION; ENDOSOME; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; NEUROPATHOLOGY; PARKINSON DISEASE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; WILD TYPE;

CATHEPSIN D; ENDOSOME; PARKINSON'S DISEASE; RETROMER; VPS35 D620N;

AGED; CATHEPSIN D; CELL LINE, TUMOR; CELLS, CULTURED; ENDOSOMES; HEK293 CELLS; HUMANS; MALE; MUTATION, MISSENSE; PARKINSON DISEASE; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTOR, IGF TYPE 2; VESICULAR TRANSPORT PROTEINS;

EID: 84892489531     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/tra.12136     Document Type: Article

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