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Volumn 69, Issue 2, 2014, Pages 323-330

Impact of folate supplementation on the efficacy of sulfadoxine/pyrimethamine in preventing malaria in pregnancy: The potential of 5-methyl-tetrahydrofolate

Author keywords

Antifolate; Intermittent preventive treatment during pregnancy; IPTp; Neural tube defects; NTDs; Plasmodium falciparum

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; FOLIC ACID; PYRIMETHAMINE PLUS SULFADOXINE;

EID: 84892469646     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkt394     Document Type: Review
Times cited : (19)

References (61)
  • 1
    • 75749107025 scopus 로고    scopus 로고
    • Quantifying the number of pregnancies at risk of malaria in 2007: a demographic study
    • Dellicour S, Tatem AJ, Guerra CA et al. Quantifying the number of pregnancies at risk of malaria in 2007: a demographic study. PLoS Med 2010; 7: e1000221.
    • (2010) PLoS Med , vol.7
    • Dellicour, S.1    Tatem, A.J.2    Guerra, C.A.3
  • 2
    • 33846315783 scopus 로고    scopus 로고
    • Malaria in pregnancy: pathogenesis and immunity
    • Rogerson SJ, Hviid L, Duffy PE et al. Malaria in pregnancy: pathogenesis and immunity. Lancet Infect Dis 2007; 7: 105-17.
    • (2007) Lancet Infect Dis , vol.7 , pp. 105-117
    • Rogerson, S.J.1    Hviid, L.2    Duffy, P.E.3
  • 3
    • 33846331963 scopus 로고    scopus 로고
    • Epidemiology and burden of malaria in pregnancy
    • Desai M, ter Kuile FO, Nosten F et al. Epidemiology and burden of malaria in pregnancy. Lancet Infect Dis 2007; 7: 93-104.
    • (2007) Lancet Infect Dis , vol.7 , pp. 93-104
    • Desai, M.1    Ter Kuile, F.O.2    Nosten, F.3
  • 4
    • 84860313263 scopus 로고    scopus 로고
    • Effects of malaria and its treatment in early pregnancy
    • Desai M, Dellicour S. Effects of malaria and its treatment in early pregnancy. Lancet Infect Dis 2012; 12: 359-60.
    • (2012) Lancet Infect Dis , vol.12 , pp. 359-360
    • Desai, M.1    Dellicour, S.2
  • 5
    • 67649882515 scopus 로고    scopus 로고
    • Malaria and HIV co-infection in pregnancy in sub-Saharan Africa: impact of treatment using antimalarial and antiretroviral agents
    • Uneke CJ, Ogbonna A. Malaria and HIV co-infection in pregnancy in sub-Saharan Africa: impact of treatment using antimalarial and antiretroviral agents. Trans R Soc Trop Med Hyg 2009; 103: 761-7.
    • (2009) Trans R Soc Trop Med Hyg , vol.103 , pp. 761-767
    • Uneke, C.J.1    Ogbonna, A.2
  • 6
    • 84864066704 scopus 로고    scopus 로고
    • Intermittent preventive treatment of malaria in pregnant women and infants: making best use of the available evidence
    • Bardaji A, Bassat Q, Alonso PL et al. Intermittent preventive treatment of malaria in pregnant women and infants: making best use of the available evidence. Expert Opin Pharmacother 2012; 13: 1719-36.
    • (2012) Expert Opin Pharmacother , vol.13 , pp. 1719-1736
    • Bardaji, A.1    Bassat, Q.2    Alonso, P.L.3
  • 7
    • 33846317129 scopus 로고    scopus 로고
    • Reducing the burdenof malaria in pregnancy by preventive strategies
    • Menendez C, D'Alessandro U, ter Kuile FO. Reducing the burdenof malaria in pregnancy by preventive strategies. Lancet Infect Dis 2007; 7: 126-35.
    • (2007) Lancet Infect Dis , vol.7 , pp. 126-135
    • Menendez, C.1    D'Alessandro, U.2    Ter Kuile, F.O.3
  • 8
    • 3042620883 scopus 로고    scopus 로고
    • WHO Antenatal Care Trial Research Group. (3 June 2013, date last accessed).
    • WHO Antenatal Care Trial Research Group. WHO Antenatal Care Randomized Trial: Manual for the Implementation of the New Model. 2002. http://www.who.int/reproductivehealth/publications/maternal_perinatal_ health/RHR_01_30/en/(3 June 2013, date last accessed).
    • (2002) WHO Antenatal Care Randomized Trial: Manual for the Implementation of the New Model
  • 9
    • 79952039392 scopus 로고    scopus 로고
    • Coverage of malaria protection in pregnant women in sub-Saharan Africa: a synthesis and analysis of national survey data
    • van Eijk AM, Hill J, Alegana VA et al. Coverage of malaria protection in pregnant women in sub-Saharan Africa: a synthesis and analysis of national survey data. Lancet Infect Dis 2011; 11: 190-207.
    • (2011) Lancet Infect Dis , vol.11 , pp. 190-207
    • van Eijk, A.M.1    Hill, J.2    Alegana, V.A.3
  • 10
    • 84856771745 scopus 로고    scopus 로고
    • Combination of probenecidsulphadoxine- pyrimethamine for intermittent preventive treatment in pregnancy
    • Gutman J, Kachur SP, Slutsker L et al. Combination of probenecidsulphadoxine- pyrimethamine for intermittent preventive treatment in pregnancy. Malar J 2012; 11: 39.
    • (2012) Malar J , vol.11 , pp. 39
    • Gutman, J.1    Kachur, S.P.2    Slutsker, L.3
  • 11
    • 77954985023 scopus 로고    scopus 로고
    • Maternal nutrition and birth outcomes
    • Abu-Saad K, Fraser D. Maternal nutrition and birth outcomes. Epidemiol Rev 2010; 32: 5-25.
    • (2010) Epidemiol Rev , vol.32 , pp. 5-25
    • Abu-Saad, K.1    Fraser, D.2
  • 12
    • 0031916512 scopus 로고    scopus 로고
    • Nutritional interventions to prevent intrauterine growth retardation: evidence from randomized controlled trials
    • de Onis M, Villar J, Gulmezoglu M. Nutritional interventions to prevent intrauterine growth retardation: evidence from randomized controlled trials. Eur J Clin Nutr 1998; 52 Suppl 1: S83-93.
    • (1998) Eur J Clin Nutr , vol.52 , Issue.SUPPL. 1
    • de Onis, M.1    Villar, J.2    Gulmezoglu, M.3
  • 14
    • 0028863219 scopus 로고
    • Folate levels and neural tube defects. Implications for prevention
    • Daly LE, Kirke PN, Molloy A et al. Folate levels and neural tube defects. Implications for prevention. JAMA 1995; 274: 1698-702.
    • (1995) JAMA , vol.274 , pp. 1698-1702
    • Daly, L.E.1    Kirke, P.N.2    Molloy, A.3
  • 15
    • 77951630647 scopus 로고    scopus 로고
    • Folic acid to reduce neonatal mortality fromneural tubedisorders
    • Blencowe H, Cousens S, Modell B et al. Folic acid to reduce neonatal mortality fromneural tubedisorders. Int J Epidemiol 2010;39Suppl 1: i110-21.
    • (2010) Int J Epidemiol , vol.39 , Issue.SUPPL. 1
    • Blencowe, H.1    Cousens, S.2    Modell, B.3
  • 16
    • 65649140113 scopus 로고    scopus 로고
    • Folic acid supplementation for the prevention of neural tube defects: an update of the evidence for the U.S. Preventive Services Task Force
    • WolffT, Witkop CT, Miller T et al. Folic acid supplementation for the prevention of neural tube defects: an update of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med 2009; 150: 632-9.
    • (2009) Ann Intern Med , vol.150 , pp. 632-639
    • Wolff, T.1    Witkop, C.T.2    Miller, T.3
  • 18
    • 34249652348 scopus 로고    scopus 로고
    • Folic acid and the decline in neural tube defects in Arkansas
    • Mosley BS, Hobbs CA, Flowers BS et al. Folic acid and the decline in neural tube defects in Arkansas. J Ark Med Soc 2007; 103: 247-50.
    • (2007) J Ark Med Soc , vol.103 , pp. 247-250
    • Mosley, B.S.1    Hobbs, C.A.2    Flowers, B.S.3
  • 19
    • 84869457151 scopus 로고    scopus 로고
    • Neural tube defects and maternal intake of micronutrients related to one-carbon metabolism or antioxidant activity
    • Chandler AL, Hobbs CA, Mosley BS et al. Neural tube defects and maternal intake of micronutrients related to one-carbon metabolism or antioxidant activity. Birth Defects Res A Clin Mol Teratol 2012; 94:864-74.
    • (2012) Birth Defects Res A Clin Mol Teratol , vol.94 , pp. 864-874
    • Chandler, A.L.1    Hobbs, C.A.2    Mosley, B.S.3
  • 20
    • 84860672426 scopus 로고    scopus 로고
    • Malaria drug resistance:newobservations and developments
    • Sa JM, Chong JL, Wellems TE. Malaria drug resistance:newobservations and developments. Essays Biochem 2011; 51: 137-60.
    • (2011) Essays Biochem , vol.51 , pp. 137-160
    • Sa, J.M.1    Chong, J.L.2    Wellems, T.E.3
  • 21
    • 19444371029 scopus 로고    scopus 로고
    • Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy
    • Nzila A, Ward SA, Marsh K et al. Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy. Trends Parasitol 2005; 21: 292-8.
    • (2005) Trends Parasitol , vol.21 , pp. 292-298
    • Nzila, A.1    Ward, S.A.2    Marsh, K.3
  • 22
    • 0030962568 scopus 로고    scopus 로고
    • Unmetabolized folic acid in serum: acute studies in subjects consuming fortified food and supplements
    • Kelly P, McPartlin J, Goggins M et al. Unmetabolized folic acid in serum: acute studies in subjects consuming fortified food and supplements. Am J Clin Nutr 1997; 65: 1790-5.
    • (1997) Am J Clin Nutr , vol.65 , pp. 1790-1795
    • Kelly, P.1    McPartlin, J.2    Goggins, M.3
  • 23
    • 33748755472 scopus 로고    scopus 로고
    • The past, present and future of antifolates in the treatment of Plasmodium falciparum infection
    • Nzila A. The past, present and future of antifolates in the treatment of Plasmodiumfalciparuminfection. JAntimicrobChemother2006;57:1043-54.
    • (2006) J Antimicrob Chemother , vol.57 , pp. 1043-1054
    • Nzila, A.1
  • 24
    • 70350616263 scopus 로고    scopus 로고
    • Discovery, mechanisms of action and combination therapy of artemisinin
    • Cui L, Su XZ. Discovery, mechanisms of action and combination therapy of artemisinin. Expert Rev Anti Infect Ther 2009; 7: 999-1013.
    • (2009) Expert Rev Anti Infect Ther , vol.7 , pp. 999-1013
    • Cui, L.1    Su, X.Z.2
  • 25
    • 77956487852 scopus 로고    scopus 로고
    • Anti-folate drug resistance in Africa: meta-analysis of reported dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant genotype frequencies in African Plasmodium falciparum parasite populations
    • Sridaran S, McClintock SK, Syphard LM et al. Anti-folate drug resistance in Africa: meta-analysis of reported dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant genotype frequencies in African Plasmodium falciparum parasite populations. Malar J 2010; 9: 247.
    • (2010) Malar J , vol.9 , pp. 247
    • Sridaran, S.1    McClintock, S.K.2    Syphard, L.M.3
  • 26
    • 80051670674 scopus 로고    scopus 로고
    • Scaling up of intermittent preventive treatment of malaria in pregnancy using sulphadoxine-pyrimethamine: prospects and challenges
    • Oyibo WA, Agomo CO. Scaling up of intermittent preventive treatment of malaria in pregnancy using sulphadoxine-pyrimethamine: prospects and challenges. Matern Child Health J 2011; 15: 542-52.
    • (2011) Matern Child Health J , vol.15 , pp. 542-552
    • Oyibo, W.A.1    Agomo, C.O.2
  • 27
    • 79958830015 scopus 로고    scopus 로고
    • Intermittent preventive treatment of malaria in pregnancy: at the crossroads of public health policy
    • Chico RM, Chandramohan D. Intermittent preventive treatment of malaria in pregnancy: at the crossroads of public health policy. Trop Med Int Health 2011; 16: 774-85.
    • (2011) Trop Med Int Health , vol.16 , pp. 774-785
    • Chico, R.M.1    Chandramohan, D.2
  • 28
    • 70349423602 scopus 로고    scopus 로고
    • Intermittent treatment for the prevention of malaria during pregnancy in Benin: a randomized, open-label equivalence trial comparing sulfadoxine-pyrimethamine with mefloquine
    • Briand V, Bottero J, Noel H et al. Intermittent treatment for the prevention of malaria during pregnancy in Benin: a randomized, open-label equivalence trial comparing sulfadoxine-pyrimethamine with mefloquine. J Infect Dis 2009; 200: 991-1001.
    • (2009) J Infect Dis , vol.200 , pp. 991-1001
    • Briand, V.1    Bottero, J.2    Noel, H.3
  • 29
    • 70349656475 scopus 로고    scopus 로고
    • Randomized trial of piperaquine with sulfadoxine-pyrimethamine or dihydroartemisinin for malaria intermittent preventive treatment in children
    • Cisse B, Cairns M, Faye E et al. Randomized trial of piperaquine with sulfadoxine-pyrimethamine or dihydroartemisinin for malaria intermittent preventive treatment in children. PLoS One 2009; 4: e7164.
    • (2009) PLoS One , vol.4
    • Cisse, B.1    Cairns, M.2    Faye, E.3
  • 30
    • 0033027433 scopus 로고    scopus 로고
    • The antimalarial triazine WR99210 and the prodrug PS-15: folate reversal of in vitro activity against Plasmodium falciparum and a non-antifolate mode of action of the prodrug
    • Kinyanjui SM, Mberu EK, Winstanley PA et al. The antimalarial triazine WR99210 and the prodrug PS-15: folate reversal of in vitro activity against Plasmodium falciparum and a non-antifolate mode of action of the prodrug. Am J Trop Med Hyg 1999; 60: 943-7.
    • (1999) Am J Trop Med Hyg , vol.60 , pp. 943-947
    • Kinyanjui, S.M.1    Mberu, E.K.2    Winstanley, P.A.3
  • 31
    • 42049115684 scopus 로고    scopus 로고
    • Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer
    • Nduati E, Diriye A, Ommeh S et al. Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer. Parasitol Res 2008; 102: 1227-34.
    • (2008) Parasitol Res , vol.102 , pp. 1227-1234
    • Nduati, E.1    Diriye, A.2    Ommeh, S.3
  • 32
    • 38549128269 scopus 로고    scopus 로고
    • Folic acid metabolism and malaria
    • Metz J. Folic acid metabolism and malaria. Food Nutr Bull 2007; 28:S540-9.
    • (2007) Food Nutr Bull , vol.28
    • Metz, J.1
  • 33
    • 0030868588 scopus 로고    scopus 로고
    • A modified in vitro sulfadoxine susceptibility assay for Plasmodium falciparum suitable for investigating Fansidar resistance
    • Wang P, Sims PF, Hyde JE. A modified in vitro sulfadoxine susceptibility assay for Plasmodium falciparum suitable for investigating Fansidar resistance. Parasitology 1997; 115: 223-30.
    • (1997) Parasitology , vol.115 , pp. 223-230
    • Wang, P.1    Sims, P.F.2    Hyde, J.E.3
  • 34
    • 0030813699 scopus 로고    scopus 로고
    • The efficacy of antifolate antimalarial combinations in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses
    • Watkins WM, Mberu EK, Winstanley PA et al. The efficacy of antifolate antimalarial combinations in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses. Parasitol Today 1997;13: 459-64.
    • (1997) Parasitol Today , vol.13 , pp. 459-464
    • Watkins, W.M.1    Mberu, E.K.2    Winstanley, P.A.3
  • 35
    • 0019423221 scopus 로고
    • Increased accumulation of methotrexate by murine tumor cells in vitro in the presence of probenecid which is mediated by a preferential inhibition of efflux
    • Sirotnak FM, Moccio DM, Young CW. Increased accumulation of methotrexate by murine tumor cells in vitro in the presence of probenecid which is mediated by a preferential inhibition of efflux. Cancer Res 1981;41: 966-70.
    • (1981) Cancer Res , vol.41 , pp. 966-970
    • Sirotnak, F.M.1    Moccio, D.M.2    Young, C.W.3
  • 36
    • 0033813261 scopus 로고    scopus 로고
    • Co-administration of probenecid, an inhibitor of a cMOAT/MRP-like plasma membrane ATPase, greatly enhanced the efficacy of a new 10-deazaaminopterin against human solid tumors in vivo
    • Sirotnak FM, Wendel HG, Bornmann WG et al. Co-administration of probenecid, an inhibitor of a cMOAT/MRP-like plasma membrane ATPase, greatly enhanced the efficacy of a new 10-deazaaminopterin against human solid tumors in vivo. Clin Cancer Res 2000; 6: 3705-12.
    • (2000) Clin Cancer Res , vol.6 , pp. 3705-3712
    • Sirotnak, F.M.1    Wendel, H.G.2    Bornmann, W.G.3
  • 37
    • 0038676970 scopus 로고    scopus 로고
    • Chemosensitization of Plasmodium falciparum by probenecid in vitro
    • Nzila A, Mberu E, Bray P et al. Chemosensitization of Plasmodium falciparum by probenecid in vitro. Antimicrob Agents Chemother 2003; 47:2108-12.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 2108-2112
    • Nzila, A.1    Mberu, E.2    Bray, P.3
  • 38
    • 84455169978 scopus 로고    scopus 로고
    • The molecular basis of folate salvage in Plasmodium falciparum: characterization of two folate transporters
    • Salcedo-Sora JE, Ochong E, Beveridge S et al. The molecular basis of folate salvage in Plasmodium falciparum: characterization of two folate transporters. J Biol Chem 2011; 286: 44659-68.
    • (2011) J Biol Chem , vol.286 , pp. 44659-44668
    • Salcedo-Sora, J.E.1    Ochong, E.2    Beveridge, S.3
  • 39
    • 34249934338 scopus 로고    scopus 로고
    • Characterisation of exogenous folate transport in Plasmodium falciparum
    • Wang P, Wang Q, Sims PF et al. Characterisation of exogenous folate transport in Plasmodium falciparum. Mol Biochem Parasitol 2007; 154:40-51.
    • (2007) Mol Biochem Parasitol , vol.154 , pp. 40-51
    • Wang, P.1    Wang, Q.2    Sims, P.F.3
  • 40
    • 10944244308 scopus 로고    scopus 로고
    • Comparative effects of pyrimethaminesulfadoxine, with and without probenecid, on Plasmodium falciparum gametocytes in children with acute, uncomplicated malaria
    • Sowunmi A, Adedeji AA et al. Comparative effects of pyrimethaminesulfadoxine, with and without probenecid, on Plasmodium falciparum gametocytes in children with acute, uncomplicated malaria. Ann Trop Med Parasitol 2004; 98: 873-8.
    • (2004) Ann Trop Med Parasitol , vol.98 , pp. 873-878
    • Sowunmi, A.1    Adedeji, A.A.2
  • 41
    • 2442661324 scopus 로고    scopus 로고
    • Open randomized study of pyrimethamine-sulphadoxine vs. pyrimethamine-sulphadoxine plus probenecid for the treatment of uncomplicated Plasmodium falciparum malaria in children
    • Sowunmi A, Fehintola FA, Adedeji AA et al. Open randomized study of pyrimethamine-sulphadoxine vs. pyrimethamine-sulphadoxine plus probenecid for the treatment of uncomplicated Plasmodium falciparum malaria in children. Trop Med Int Health 2004; 9: 606-14.
    • (2004) Trop Med Int Health , vol.9 , pp. 606-614
    • Sowunmi, A.1    Fehintola, F.A.2    Adedeji, A.A.3
  • 42
    • 0029557546 scopus 로고
    • Iron, but not folicacid, combined with effective antimalarial therapy promotes haematological recovery in African children after acute falciparum malaria
    • vanHensbroek MB, Morris-Jones S, Meisner S et al. Iron, but not folicacid, combined with effective antimalarial therapy promotes haematological recovery in African children after acute falciparum malaria. Trans R Soc Trop Med Hyg 1995; 89: 672-6.
    • (1995) Trans R Soc Trop Med Hyg , vol.89 , pp. 672-676
    • van Hensbroek, M.B.1    Morris-Jones, S.2    Meisner, S.3
  • 43
    • 24644470524 scopus 로고    scopus 로고
    • Reduction of the efficacy of antifolate antimalarial therapy by folic acid supplementation
    • Carter JY, Loolpapit MP, Lema OE et al. Reduction of the efficacy of antifolate antimalarial therapy by folic acid supplementation. Am J Trop Med Hyg 2005; 73: 166-70.
    • (2005) Am J Trop Med Hyg , vol.73 , pp. 166-170
    • Carter, J.Y.1    Loolpapit, M.P.2    Lema, O.E.3
  • 44
    • 33746071614 scopus 로고    scopus 로고
    • Folic acid treatment of Zambian children with moderate to severe malaria anemia
    • Mulenga M, Malunga P, Bennett S et al. Folic acid treatment of Zambian children with moderate to severe malaria anemia. AmJ Trop Med Hyg 2006;74: 986-90.
    • (2006) Am J Trop Med Hyg , vol.74 , pp. 986-990
    • Mulenga, M.1    Malunga, P.2    Bennett, S.3
  • 45
    • 77955338002 scopus 로고    scopus 로고
    • Inhibiting Plasmodium cytochrome bc1: a complex issue
    • Barton V, Fisher N, Biagini GA et al. Inhibiting Plasmodium cytochrome bc1: a complex issue. Curr Opin Chem Biol 2010; 14: 440-6.
    • (2010) Curr Opin Chem Biol , vol.14 , pp. 440-446
    • Barton, V.1    Fisher, N.2    Biagini, G.A.3
  • 46
    • 18244404066 scopus 로고    scopus 로고
    • Blood folate concentrations and in vivo sulfadoxine-pyrimethamine failure in Malawian children with uncomplicated Plasmodium falciparum malaria
    • Dzinjalamala FK, Macheso A, Kublin JG et al. Blood folate concentrations and in vivo sulfadoxine-pyrimethamine failure in Malawian children with uncomplicated Plasmodium falciparum malaria. Am J Trop Med Hyg 2005;72: 267-72.
    • (2005) Am J Trop Med Hyg , vol.72 , pp. 267-272
    • Dzinjalamala, F.K.1    Macheso, A.2    Kublin, J.G.3
  • 47
    • 33846438002 scopus 로고    scopus 로고
    • A randomized controlled trial of folate supplementation when treating malaria in pregnancy with sulfadoxine-pyrimethamine
    • Ouma P, Parise ME, Hamel MJ et al. A randomized controlled trial of folate supplementation when treating malaria in pregnancy with sulfadoxine-pyrimethamine. PLoS Clin Trials 2006; 1: e28.
    • (2006) PLoS Clin Trials , vol.1
    • Ouma, P.1    Parise, M.E.2    Hamel, M.J.3
  • 48
    • 54949121788 scopus 로고    scopus 로고
    • Plasma folate level and high-dose folate supplementation predict sulfadoxine-pyrimethamine treatment failure in pregnant women in Western Kenya who have uncomplicated malaria
    • van Eijk AM, Ouma PO, Williamson J et al. Plasma folate level and high-dose folate supplementation predict sulfadoxine-pyrimethamine treatment failure in pregnant women in Western Kenya who have uncomplicated malaria. J Infect Dis 2008; 198: 1550-3.
    • (2008) J Infect Dis , vol.198 , pp. 1550-1553
    • van Eijk, A.M.1    Ouma, P.O.2    Williamson, J.3
  • 49
    • 33746042261 scopus 로고    scopus 로고
    • Lack of inhibition of the antimalarial action of sulfadoxine-pyrimethamine by folic acid supplementation when used for intermittent preventive treatment in Gambian primigravidae
    • Mbaye A, Richardson K, Balajo B et al. Lack of inhibition of the antimalarial action of sulfadoxine-pyrimethamine by folic acid supplementation when used for intermittent preventive treatment in Gambian primigravidae. Am J Trop Med Hyg 2006; 74: 960-4.
    • (2006) Am J Trop Med Hyg , vol.74 , pp. 960-964
    • Mbaye, A.1    Richardson, K.2    Balajo, B.3
  • 50
    • 0033560719 scopus 로고    scopus 로고
    • Inhibition of the peroxidative degradation of haem as the basis of action of chloroquine and other quinoline antimalarials
    • Loria P, Miller S, Foley M et al. Inhibition of the peroxidative degradation of haem as the basis of action of chloroquine and other quinoline antimalarials. Biochem J 1999; 339: 363-70.
    • (1999) Biochem J , vol.339 , pp. 363-370
    • Loria, P.1    Miller, S.2    Foley, M.3
  • 51
    • 33847413750 scopus 로고    scopus 로고
    • Transport of the essential nutrient isoleucine inhuman erythrocytes infected with the malaria parasite Plasmodium falciparum
    • Martin RE, Kirk K. Transport of the essential nutrient isoleucine inhuman erythrocytes infected with the malaria parasite Plasmodium falciparum. Blood 2007; 109: 2217-24.
    • (2007) Blood , vol.109 , pp. 2217-2224
    • Martin, R.E.1    Kirk, K.2
  • 52
    • 78650179407 scopus 로고    scopus 로고
    • Methionine transport in the malaria parasite Plasmodium falciparum
    • Cobbold SA, Martin RE, Kirk K. Methionine transport in the malaria parasite Plasmodium falciparum. Int J Parasitol 2011; 41: 125-35.
    • (2011) Int J Parasitol , vol.41 , pp. 125-135
    • Cobbold, S.A.1    Martin, R.E.2    Kirk, K.3
  • 53
    • 0027263498 scopus 로고
    • The methionine synthesis cycle and salvage of methyltetrahydrofolate from host red cells in the malaria parasite (Plasmodium falciparum)
    • Asawamahasakda W, Yuthavong Y. The methionine synthesis cycle and salvage of methyltetrahydrofolate from host red cells in the malaria parasite (Plasmodium falciparum). Parasitology 1993; 107: 1-10.
    • (1993) Parasitology , vol.107 , pp. 1-10
    • Asawamahasakda, W.1    Yuthavong, Y.2
  • 54
    • 84888632736 scopus 로고    scopus 로고
    • Is 5-methyltetrahydrofolate an alternative to folic acid for the prevention of neural tube defects?
    • Obeid R, Holzgreve W, Pietrzik K. Is 5-methyltetrahydrofolate an alternative to folic acid for the prevention of neural tube defects? J Perinat Med 2013; 41: 469-83.
    • (2013) J Perinat Med , vol.41 , pp. 469-483
    • Obeid, R.1    Holzgreve, W.2    Pietrzik, K.3
  • 55
    • 77954516516 scopus 로고    scopus 로고
    • Folic acid and L-5-methyltetrahydro-folate: comparison of clinical pharmacokinetics and pharmacodynamics
    • Pietrzik K, Bailey L, Shane B. Folic acid and L-5-methyltetrahydro-folate: comparison of clinical pharmacokinetics and pharmacodynamics. Clin Pharmacokinet 2010; 49: 535-48.
    • (2010) Clin Pharmacokinet , vol.49 , pp. 535-548
    • Pietrzik, K.1    Bailey, L.2    Shane, B.3
  • 56
    • 34748912412 scopus 로고    scopus 로고
    • Folic acid metabolism in human subjects revisited: potential implications for proposed mandatory folic acid fortification in the UK
    • Wright AJ, Dainty JR, Finglas PM. Folic acid metabolism in human subjects revisited: potential implications for proposed mandatory folic acid fortification in the UK. Br J Nutr 2007; 98: 667-75.
    • (2007) Br J Nutr , vol.98 , pp. 667-675
    • Wright, A.J.1    Dainty, J.R.2    Finglas, P.M.3
  • 57
    • 0034691317 scopus 로고    scopus 로고
    • Controlled comparison of L-5-methyltetrahydrofolate versus folic acid for the treatment of hyperhomocysteinemia in hemodialysis patients
    • Bostom AG, Shemin D, Bagley P et al. Controlled comparison of L-5-methyltetrahydrofolate versus folic acid for the treatment of hyperhomocysteinemia in hemodialysis patients. Circulation 2000; 101: 2829-32.
    • (2000) Circulation , vol.101 , pp. 2829-2832
    • Bostom, A.G.1    Shemin, D.2    Bagley, P.3
  • 58
    • 70349324816 scopus 로고    scopus 로고
    • The extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intake
    • Bailey SW, Ayling JE. The extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intake. Proc Natl Acad Sci USA 2009; 106: 15424-9.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 15424-15429
    • Bailey, S.W.1    Ayling, J.E.2
  • 59
    • 84892455379 scopus 로고    scopus 로고
    • (1 June 2013, date last accessed).
    • Babior BM. Chapter 37, The Megaloblastic Anemias. http://medtextfree. wordpress.com/2011/12/27/chapter-37-the-megaloblastic-anemias/(1 June 2013, date last accessed).
    • Chapter 37, The Megaloblastic Anemias
    • Babior, B.M.1
  • 60
    • 0035894581 scopus 로고    scopus 로고
    • Quantifying the effect of folic acid
    • Wald NJ, Law MR, Morris JK et al. Quantifying the effect of folic acid. Lancet 2001; 358: 2069-73.
    • (2001) Lancet , vol.358 , pp. 2069-2073
    • Wald, N.J.1    Law, M.R.2    Morris, J.K.3
  • 61
    • 33646705408 scopus 로고    scopus 로고
    • [6S]-5-Methyltetrahydrofolate is at least as effective as folic acid in preventing a decline in blood folate concentrations during lactation
    • Houghton LA, Sherwood KL et al. [6S]-5-Methyltetrahydrofolate is at least as effective as folic acid in preventing a decline in blood folate concentrations during lactation. Am J Clin Nutr 2006; 83: 842-50.
    • (2006) Am J Clin Nutr , vol.83 , pp. 842-850
    • Houghton, L.A.1    Sherwood, K.L.2


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