Effects of rhaponticum carthamoides versus glycyrrhiza glabra and punica granatum extracts on metabolic syndrome signs in rats

BMC Complementary and Alternative Medicine

Volumn 14, Issue , 2014, Pages

  Dushkin, Michael ^a,b   Khrapova, Marina ^a   Kovshik, Gennadiy ^b   Chasovskikh, Marina ^a   Menshchikova, Elena ^c   Trufakin, Valeriy ^b   Shurlygina, Anna ^b   Vereschagin, Evgeniy ^a  

^a INSTITUTE OF PHYSIOLOGY   (Russian Federation)

^b SCIENTIFIC RESEARCH INSTITUTE OF PHYSIOLOGY AND BASIC MEDICINE   (Russian Federation)

^c ENERGY SYSTEMS INSTITUTE   (Russian Federation)

Author keywords

Corticosterone; Inflammatory cytokines; Metabolic syndrome; Rhaponticum carthamoides

Indexed keywords

CORTICOSTERONE; GLYCYRRHIZA GLABRA EXTRACT; INTERLEUKIN 6; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; POMEGRANATE EXTRACT; TRIACYLGLYCEROL; GLUCOSE BLOOD LEVEL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PLANT EXTRACT; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA BINDING; DYSLIPIDEMIA; ENZYME ACTIVITY; EPIDIDYMIS FAT; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; GLYCYRRHIZA GLABRA; LIPID BLOOD LEVEL; MALE; METABOLIC SYNDROME X; NONHUMAN; PLANT ROOT; POMEGRANATE; RAT; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; BLOOD; BLOOD PRESSURE; BODY WEIGHT; COMPARATIVE STUDY; DIET SUPPLEMENTATION; DISEASE MODEL; DRUG EFFECTS; FATTY LIVER; GLYCYRRHIZA; LEUZEA; LIPID DIET; LIPID METABOLISM; LIVER; LYTHRACEAE; METABOLISM; PHYTOTHERAPY; WISTAR RAT;

ANIMALS; BLOOD GLUCOSE; BLOOD PRESSURE; BODY WEIGHT; DIET, HIGH-FAT; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; FATTY LIVER; GLUCOSE INTOLERANCE; GLYCYRRHIZA; LEUZEA; LIPID METABOLISM; LIVER; MALE; METABOLIC SYNDROME X; PHYTOTHERAPY; PLANT EXTRACTS; PPAR ALPHA; PUNICACEAE; RATS, WISTAR; TRIGLYCERIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84892447185     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-14-33     Document Type: Article

References (41)

1. Mottilo S, Filion KB, Genest J, Joseph L, Pilote L, Poirier P, Rinfret S, Schiffrin EL, Eisemberg MJ. The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis. J Am Coll Cardiol 2010, 56(14):1113-1132. 10.1016/j.jacc.2010.05.034, 20863953.
2. Pereira MA, Kottke TE, Jordan C, O'Connor PJ, Pronk NP, Carreon R. Preventing and managing cardiometabolic risk: the logic for intervention. Int J Environ Res Public Health 2009, 6(10):2568-2584. 10.3390/ijerph6102568, 2790093, 20054455.
3. Del Ben M, Baratta F, Polimeni L, Angelico F. Non-alcogolic fatty liver disease and cardiovascular disease: epidemiological, clinical and phathophysiological evidences. Intern Emerg Med 2012, 7(Suppl. 3):S291-S296.
4. Prasad H, Ryan DA, Celzo MF, Stapleton D. Metabolic syndrome: definition and therapeutic implication. Postgrad Med 2012, 124(1):21-30.
5. Michos ED, Sibley CT, Baer JT, Blaha MJ, Blumental RS. Niacin and statin combination therapy for atherosclerosis regression and prevention of cardiovascular disease events: reconciling the AIM-HIGH (Aterothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglicerides: impact on global health outcomes) trial with previous surrogate endpoint trials. J Am Coll Cardiol 2012, 59(23):2058-2064. 10.1016/j.jacc.2012.01.045, 22520249.
6. Nseir W, Mograbi J, Ghali M. Lipid lowering agents in nonalcogol fatty liver disease and steatohepatitis: human studies. Dig Dis Sci 2012, 57(7):1773-1781. 10.1007/s10620-012-2118-3, 22419057.
7. Filippatos TD. A review of time courses and predictors of lipid changes with fenofibric acid-statin combination. Cardiovasc Drug Ther 2012, 26(3):245-255.
8. Power M, Pratley R. Alternative and complementary treatments for metabolic syndrome. Curr Diab Rep 2011, 11(3):173-178. 10.1007/s11892-011-0184-0, 21336843.
9. Huang TH, Teoh AW, Lin BL, Lin DS, Roufogalis B. The role of herbal PPAR modulators in the treatment of cardiomatabolic syndrome. Pharmacol Res 2009, 60(3):195-206. 10.1016/j.phrs.2009.03.020, 19646659.
10. Cherniak EP. Polyphenols: planting the seeds of treatment for metabolic syndrome. Nutrition 2011, 27(6):617-623. 10.1016/j.nut.2010.10.013, 21367579.
11. Laksmidevi N, Maharadeva MS, Prakash HS, Niranjana SR. Diabetes and medical plants-a review. Int J Pharm Biomed Sci 2011, 2(3):65-80.
12. Babich JG, Pacioretty LM, Bland JS, Minich DM, Hu J, Tripp ML. Antidiabetic screening of commercial botanical products in 3 T3-L1 adipocytes ad db/db mice. J Med Food 2010, 13(3):535-547. 10.1089/jmf.2009.0110, 20521979.
13. Eu CH, Lim WY, Ton SH, bin Abdul Kadir K. Glycyrrhizic acid improved lipoprotein lipase expression, insulin sensitivity, serum lipid and lipid lipid deposition in high-fat diet-induced obese rats. Lipid Health Dis 2010, 9:81.
14. Jungbauer A, Medjakovic S. Phytoestrogens and the metabolic syndrome. J Steroid Biochem Mol Biol 2014, 139:277-289.
15. Al-Muammar MN, Khan F. Obesity: the preventive role of the pomegranate (Punica granatum). Nutrition 2012, 28(6):595-604. 10.1016/j.nut.2011.11.013, 22342388.
16. Medjakovic S, Jungbauer A. Pomegranate: a fruit that ameliorates metabolic syndrome. Food Funct 2013, 4:19-39. 10.1039/c2fo30034f, 23060097.
17. Nakagawa K, Kishida H, Arai N, Nishiyama T, Mae T. Licorice flavonoids suppress abdominal fat accumulation and increase in blood glucose level in obese diabetic KK-A(y) mice. Biol Pharm Bull 2004, 27(11):1775-1778. 10.1248/bpb.27.1775, 15516721.
18. Honda K, Kamisoyama H, Tominaga Y, Yokota S, Hasegawa S. The molecular mechanism underlying the reduction in abdominal fat accumulation by licorice flavonoids oil in high fat diet-induced obesity rats. Anim Sci J 2009, 80(5):362-569.
19. Parmar HS, Kar A. Antidiabetic potential of Citrus sinensis and Punica granatum peel extracts in alloxan treated male mice. Biofactors 2007, 31(1):17-24. 10.1002/biof.5520310102, 18806305.
20. Parmar HS, Kar A. Medical values of fruit peels from Citrus sinensis, Punica granatum, and Musa paradisiacal with respect to alterations in tissue lipid peraxidation and serum concentration of glucose, insulin, and thyroid hormones. J Med Food 2008, 11(2):376-381. 10.1089/jmf.2006.010, 18598183.
21. Kokoska L, Janovska D. Chemistry and pharmacology of Rhaponticum carthamodies: a review. Phytochemistry 2009, 70(7):842-855. 10.1016/j.phytochem.2009.04.008, 19457517.
22. Hara A, Radin NS. Lipid extraction of tissues with a low toxicity solvent. Anal Biochem 1978, 90(1):420-426. 10.1016/0003-2697(78)90046-5, 727482.
23. Kang X, Zhong W, Liu J, Song Z, McClaim CJ, Kang YJ, Zhou Z. Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha. Hepatology 2009, 50(4):1241-1250. 10.1002/hep.23090, 2757527, 19637192.
24. Plotnikov MV, Vasilev AS, Aliev OI, Anishenko AM, Krasnov EA. Effect of Rhaponticum carthamodies exstact in combination with doses physical load on hemorheological parameters of rats with myocardial infarction. Eksp Klin Farmakol 2011, 74(9):7-10.
25. Peschel W, Kump A, Prieto JM. Effect of 20-hydroxyecdysone, Leuzea carthamodies exstracts, dexamethasone and their combinations on the NF-κB activation in HeLa cells. J Pharm Pharmacol 2011, 63(11):1483-1495. 10.1111/j.2042-7158.2011.01349.x, 21988429.
26. Nosáĺ R, Perečko T, Jančinová V, Drábiková K, Harmatha J, Sviteková K. Naturally appearing N-feruloyserotonine isomers suppress oxidative burst of human neutrophils at the protein kinase C level. Pharmacol Rep 2011, 63(3):790-798.
27. Koleckar V, Opletal L, Macakova K, Jahodar L, Jun D, Kunes J, Kuca K. New antioxidants flovonoid isolated from Leuzea carthamoides. J Enzyme Inhib Med Chem 2010, 25(1):143-145. 10.3109/14756360903090970, 20030518.
28. Kizelstein P, Govorko D, Komarnytsky S, Evans A, Wang Z, Cefalu WT, Raskin I. 20-hydroxyecdysone decreases weight and hyperglycemia in diet-induced obesity mice model. Am J Physiol Endocrinol Metab 2009, 296(3):433-439.
29. Seidlova-Wittke D, Ehrhardt C, Wuttke W. Metabolic effects of 20-OH-ecdisone in ovariectomized rats. J Steroid Biochem Mol Biol 2010, 119(3-5):121-126.
30. Mironova VN, Kholodova ID, Skachkova TF, Bondar' OP, Datsenko ZM. Hypocholesterolemic effect of phytoecdysones during experimental hypercholesterolemia in rats. Vopr Med Khim 1982, 28(2):101-105.
31. Wang S, Liu S, Liu H, Wang J, Zhou S, Jiang RJ, Bendena WG, Li S. 20-hydroxyecdysone reduces insect food consumption resulting in fat body lipolysis during molting and pupation. J Mol Cell Biol 2010, 2(3):128-138. 10.1093/jmcb/mjq006, 20430856.
32. King-Jones K, Thummel CS. Nuclear receptors - a perspective from Drosophila. Nat Rev Genet 2005, 6(4):311-323. 10.1038/nrg1581, 15803199.
33. Kumpun S, Girault JP, Dinan L, Blais C, Maria A, Dauphin-Villemant C, Yingyongnarongkul B, Suksamrarn A, Lafont R. The metabolism of 20-hydroxyecdysone in mice: relevance to pharmacological effects and gene switch applications of ecdisteroids. J Steroid Biochem Mol Biol 2011, 126(1-2):1-9.
34. Steinberg HH, Sorensen HN, Tugwood JD, Skrede S, Spydevold O, Gautvik KM. Dexametasone and insulin demonstrate marcked and opposite regulation of the steady-state mRNA level of peroxisomal proliferator-activated receptor in hepatic cells. Hormonal modulation of fatty acid-induced transcription. Eur J Biochem 1994, 225(3):967-974. 10.1111/j.1432-1033.1994.0967b.x, 7957233.
35. Anagnostis P, Athyros VG, Tziomalos K, Karagiannis A, Mikhailidis DP. Clinical review: the pathogenetic role of cortisol in metabolic syndrome: a hypothesis. J Clin Endocrinol Metab 2009, 94(8):2692-2701. 10.1210/jc.2009-0370, 19470627.
36. Scarpellini E, Tack J. Obesity and metabolic syndrome: an inflammatory condition. Dig Dis 2012, 30(2):148-153. 10.1159/000336664, 22722429.
37. Pratchayasakul W, Kerdphoo S, Petsophonsakul P, Pongchaidecha A, Chattipakorn N, Chattipakorn SC. Effect of high-fat diet on insulin receptor function in rat hippocampus and the level of neuronal corticosterone. Life Sci 2011, 88(13-14):619-627.
38. Fu JH, Xie SR, Kong SJ, Wang Y, Wei W, Shan Y, Luo YM. The combination of high-fat diet and chronic stress aggravates insulin resistance in Wistar male rats. Exp Clin Endocrinol Diabetes 2009, 117(7):354-360. 10.1055/s-0028-1119406, 19358094.
39. Celic M, Karakus A, Zeren C, Demir M, Bayarogullari H, Duru M, Al M. Licorice induced hypokalemia, edema, and thrombocytopenia. Hum Exp Toxicol 2012, 31(12):1295-1298. 10.1177/0960327112446843, 22653692.
40. Na L, Jun-tian L, Qiang-zong Z. Ellagic acid-induced hypercoagulable state in animals: a potentially useful animal hypercoagulable model for evaluation of anticoagulants. Clin Med Sci J 2010, 25(4):237-242.
41. Panichayupakaranant P, Itsuriya A, Sirikatitham A. Preparation method and stability of ellagic acid-rich pomegranate fruit peel extract. Pharm Biol 2010, 48(2):201-205. 10.3109/13880200903078503, 20645841.