Prenatal caffeine ingestion induces transgenerational neuroendocrine metabolic programming alteration in second generation rats

Toxicology and Applied Pharmacology

Volumn 274, Issue 3, 2014, Pages 383-392

  Luo, Hanwen ^a,b   Deng, Zixin ^a   Liu, Lian ^a   Shen, Lang ^a   Kou, Hao ^a   He, Zheng ^a   Ping, Jie ^a,c   Xu, Dan ^a,c   Ma, Lu ^c   Chen, Liaobin ^b   Wang, Hui ^a,c  

^a WUHAN UNIVERSITY   (China)

^b ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

^c WUHAN UNIVERSITY   (China)

Author keywords

Caffeine; Chronic stimulation; Glucose and lipid metabolism; Hypothalamus pituitary adrenal axis; Intrauterine growth retardation; Transgenerational inheritance

Indexed keywords

CAFFEINE; CORTICOSTERONE; CORTICOTROPIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CHRONIC STRESS; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INTRAUTERINE GROWTH RETARDATION; LIPID METABOLISM; MALE; MATING; METABOLIC SYNDROME X; NONHUMAN; PHENOTYPE; PRENATAL EXPOSURE; RAT; SWIMMING;

11Β-HSD2; 11Β-HYDROXYSTEROID DEHYDROGENASE 2; ACTH; ADRENOCORTICOTROPIN-RELEASING HORMONE; CAFFEINE; CHRONIC STIMULATION; CORT; CORTICOSTERONE; F1; F2; FIRST GENERATION; GC; GD; GESTATIONAL DAY; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLUCOSE AND LIPID METABOLISM; GR; HDL-C; HIGH-DENSITY LIPOPROTEIN-CHOLESTEROL; HPA; HYPOTHALAMIC-PITUITARY-ADRENAL; HYPOTHALAMUS-PITUITARY-ADRENAL AXIS; INTRAUTERINE GROWTH RETARDATION; IUGR; LDL-C; LOW-DENSITY LIPOPROTEIN-CHOLESTEROL; METABOLIC SYNDROME; MINERALOCORTICOID RECEPTOR; MR; MS; PM; POSTNATAL MONTH; POSTNATAL WEEK; PW; SECOND GENERATION; TCH; TG; TOTAL CHOLESTEROL; TRANSGENERATIONAL INHERITANCE; TRIGLYCERIDE;

ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CAFFEINE; CHOLESTEROL, HDL; CHOLESTEROL, LDL; CORTICOSTERONE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETAL GROWTH RETARDATION; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; LIPID METABOLISM; MALE; NEUROSECRETORY SYSTEMS; PITUITARY-ADRENAL SYSTEM; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR; REPRODUCTION; STRESS, PHYSIOLOGICAL; TRIGLYCERIDES;

EID: 84892446999     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.11.020     Document Type: Article

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