Dietary protein restriction during F0 pregnancy in rats induces transgenerational changes in the hepatic transcriptome in female offspring

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Hoile, Samuel P ^a   Lillycrop, Karen A ^b   Thomas, Nicola A ^a   Hanson, Mark A ^a   Burdge, Graham C ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; MESSENGER RNA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); TRANSCRIPTOME; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP);

ANIMAL EXPERIMENT; ARTICLE; CELL JUNCTION; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; EPIGENETICS; FEMALE; FETOPLACENTAL UNIT; GENE; GENE EXPRESSION REGULATION; GENE TRANSFER; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; LIVER; LYMPHOCYTE ACTIVATION GENE 3; MATERNAL NUTRITION; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS AMYLASE GENE; PHENOTYPE; PHENOTYPE ENVIRONMENT INTERACTION; PHENOTYPIC VARIATION; PHOSPHOENOLPYRUVATE CARBOXYKINASE GENE; PROGENY; PROMOTER REGION; PROTEIN RESTRICTION; RAT; SIGNAL TRANSDUCTION; TREFOIL FACTOR 2 GENE; UNINDEXED SEQUENCE; UPREGULATION; ANIMAL; CALORIC RESTRICTION; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETICS; MALE; METABOLISM; NEWBORN; PREGNANCY; PROTEIN INTAKE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WISTAR RAT;

RATTUS;

ANIMALS; ANIMALS, NEWBORN; CALORIC RESTRICTION; CPG ISLANDS; DIETARY PROTEINS; DNA METHYLATION; FEMALE; GENE EXPRESSION PROFILING; LIVER; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PREGNANCY; PROMOTER REGIONS, GENETIC; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 79960073273     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021668     Document Type: Article

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