Evaluation of cardiorespiratory fitness and respiratory muscle function in the obese population

Progress in Cardiovascular Diseases

Volumn 56, Issue 4, 2014, Pages 457-464

  Arena, Ross ^a   Cahalin, Lawrence P ^b  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Aerobic capacity; Body habitus; Expired gas analysis; Hemodynamics

Indexed keywords

AEROBIC EXERCISE; ARTICLE; BODY MASS; BREATHING MUSCLE; CARDIOPULMONARY EXERCISE TEST; CARDIORESPIRATORY FITNESS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; EXPIRATORY RESERVE VOLUME; FITNESS; HEART MUSCLE ISCHEMIA; HEART OUTPUT; HUMAN; INTERSTITIAL LUNG DISEASE; LUNG FUNCTION TEST; MUSCLE FUNCTION; OBESITY; OXYGEN CONSUMPTION; PROGNOSIS; SKELETAL MUSCLE;

AEROBIC CAPACITY; BODY HABITUS; CARBON DIOXIDE PRODUCTION; CARDIOPULMONARY EXERCISE TESTING; CARDIORESPIRATORY FITNESS; CARDIOVASCULAR; CARDIOVASCULAR DISEASES; CPX; CRF; CV; CVD; ERV; EXPIRATORY RESERVE VOLUME; EXPIRED GAS ANALYSIS; FEV(1); FORCED EXPIRATORY VOLUME AT ONE-SECOND; FORCED VITAL CAPACITY; FRC; FUNCTIONAL RESIDUAL CAPACITY; FVC; HEART RATE RECOVERY; HEMODYNAMICS; HRR; IMT; INSPIRATORY MUSCLE TRAINING; LEFT VENTRICULAR; LV; MAXIMAL EXPIRATORY PRESSURE; MAXIMAL INSPIRATORY PRESSURE; MAXIMAL VOLUNTARY VENTILATION; MEP; MET; METABOLIC EQUIVALENT; MINUTE VENTILATION; MIP; MVV; OUES; OXYGEN CONSUMPTION; OXYGEN UPTAKE EFFICIENCY SLOPE; PFT; PULMONARY FUNCTION TEST; RESIDUAL VOLUME; RV; SBP; SYSTOLIC BLOOD PRESSURE; TLC; TOTAL LUNG CAPACITY; VCO(2); VE; VO(2);

CARDIOVASCULAR PHYSIOLOGICAL PHENOMENA; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; HUMANS; MALE; OBESITY; PHYSICAL FITNESS; PROGNOSIS; RESPIRATORY FUNCTION TESTS; RESPIRATORY MECHANICS; RESPIRATORY MUSCLES; RISK ASSESSMENT;

EID: 84892437017     PISSN: 00330620     EISSN: 18731740     Source Type: Journal    
DOI: 10.1016/j.pcad.2013.08.001     Document Type: Article

References (68)

1. Arena R., Myers J., Guazzi M. The future of aerobic exercise testing in clinical practice: is it the ultimate vital sign?. Future Cardiol 2010, 6(3):325-342.
2. Di B.V., Santini F., Di C.A., et al. Relationship between preclinical abnormalities of global and regional left ventricular function and insulin resistance in severe obesity: a color Doppler imaging study. Int J Obes (Lond) 2006, 30(6):948-956.
3. Di B.V., Santini F., Di C.A., et al. Obesity cardiomyopathy: is it a reality? An ultrasonic tissue characterization study. J Am Soc Echocardiogr 2006, 19(8):1063-1071.
4. Sasson Z., Rasooly Y., Gupta R., Rasooly I. Left atrial enlargement in healthy obese: prevalence and relation to left ventricular mass and diastolic function. Can J Cardiol 1996, 12(3):257-263.
5. Galinier M., Pathak A., Roncalli J., Massabuau P. Obesity and cardiac failure. Arch Mal Coeur Vaiss 2005, 98(1):39-45.
6. Wong C., Marwick T.H. Alterations in myocardial characteristics associated with obesity: detection, mechanisms, and implications. Trends Cardiovasc Med 2007, 17(1):1-5.
7. Li J., Li S., Feuers R.J., Buffington C.K., Cowan G.S. Influence of body fat distribution on oxygen uptake and pulmonary performance in morbidly obese females during exercise. Respirology 2001, 6(1):9-13.
8. Ong P., Sivanathan R., Borgulya G., et al. Obesity, inflammation and brachial artery flow-mediated dilatation: therapeutic targets in patients with microvascular angina (cardiac syndrome X). Cardiovasc Drugs Ther 2012, 26(3):239-244.
9. Holloway G.P., Bonen A., Spriet L.L. Regulation of skeletal muscle mitochondrial fatty acid metabolism in lean and obese individuals. Am J Clin Nutr 2009, 89(1):455S-462S.
10. Ritov V.B., Menshikova E.V., He J., Ferrell R.E., Goodpaster B.H., Kelley D.E. Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes. Diabetes 2005, 54(1):8-14.
11. Runhaar J., Koes B.W., Clockaerts S., Bierma-Zeinstra S.M. A systematic review on changed biomechanics of lower extremities in obese individuals: a possible role in development of osteoarthritis. Obes Rev 2011, 12(12):1071-1082.
12. Myers J., Arena R., Franklin B., et al. Recommendations for clinical exercise laboratories: a scientific statement from the American Heart Association. Circulation 2009, 119(24):3144-3161.
13. Hulens M., Vansant G., Lysens R., Claessens A.L., Muls E. Exercise capacity in lean versus obese women. Scand J Med Sci Sports 2001, 11(5):305-309.
14. Marinov B., Kostianev S. Exercise performance and oxygen uptake efficiency slope in obese children performing standardized exercise. Acta Physiol Pharmacol Bulg 2003, 27(2-3):59-64.
15. Di Thommazo-Luporini L., Jurgensen S.P., Castello-Simoes V., Catai A.M., Arena R., Borghi-Silva A. Metabolic and clinical comparative analysis of treadmill six-minute walking test and cardiopulmonary exercise testing in obese and eutrophic women. Rev Bras Fisioter 2012, 16(6):469-478.
16. O'Donnell D.E., O'Donnell C.D., Webb K.A., Guenette J.A. Respiratory consequences of mild-to-moderate obesity: impact on exercise performance in health and in chronic obstructive pulmonary disease. Pulm Med 2012, 2012:818925.
17. Osman A.F., Mehra M.R., Lavie C.J., Nunez E., Milani R.V. The incremental prognostic importance of body fat adjusted peak oxygen consumption in chronic heart failure. J Am Coll Cardiol 2000, 36(7):2126-2131.
18. Lavie C.J., Milani R.V., Mehra M.R. Peak exercise oxygen pulse and prognosis in chronic heart failure. Am J Cardiol 2004, 93(5):588-593.
19. Ko S., Stenholm S., Ferrucci L. Characteristic gait patterns in older adults with obesity-results from the Baltimore Longitudinal Study of Aging. J Biomech 2010, 43(6):1104-1110.
20. deJong A.T., Gallagher M.J., Sandberg K.R., et al. Peak oxygen consumption and the minute ventilation/carbon dioxide production relation slope in morbidly obese men and women: influence of subject effort and body mass index. Prev Cardiol 2008, 11(2):100-105.
21. Balady G.J., Arena R., Sietsema K., et al. Clinician's guide to cardiopulmonary exercise testing in adults. A scientific statement from the american heart association. Circulation 2010, 122(2):191-225.
22. Arena R., Myers J., Guazzi M. The clinical significance of aerobic exercise testing and prescription: from apparently healthy to confirmed cardiovascular disease. Am J Lifestyle Med 2008, 2(6):519-536.
23. Carnethon M.R., Sternfeld B., Liu K., et al. Correlates of heart rate recovery over 20years in a healthy population sample. Med Sci Sports Exerc 2012, 44(2):273-279.
24. Dimkpa U., Oji J.O. Association of heart rate recovery after exercise with indices of obesity in healthy, non-obese adults. Eur J Appl Physiol 2010, 108(4):695-699.
25. Laguna M., Aznar S., Lara M.T., Lucia A., Ruiz J.R. Heart rate recovery is associated with obesity traits and related cardiometabolic risk factors in children and adolescents. Nutr Metab Cardiovasc Dis 2012, [Epub ahead of print]. pii: S0939-4753(12)00224-4. http://dx.doi.org/10.1016/j.numecd.2012.10.002.
26. Baba R., Tsuyuki K., Kimura Y., et al. Oxygen uptake efficiency slope as a useful measure of cardiorespiratory functional reserve in adult cardiac patients. Eur J Appl Physiol Occup Physiol 1999, 80(5):397-401.
27. Sun X.G., Hansen J.E., Stringer W.W. Oxygen uptake efficiency plateau: physiology and reference values. Eur J Appl Physiol 2012, 112(3):919-928.
28. Arena R., Sietsema K.E. Cardiopulmonary exercise testing in the clinical evaluation of patients with heart and lung disease. Circulation 2011, 123(6):668-680.
29. Marinov B., Kostianev S., Turnovska T. Ventilatory efficiency and rate of perceived exertion in obese and non-obese children performing standardized exercise. Clin Physiol Funct Imaging 2002, 22(4):254-260.
30. Abidov A., Rozanski A., Hachamovitch R., et al. Prognostic significance of dyspnea in patients referred for cardiac stress testing. N Engl J Med 2005, 353(18):1889-1898.
31. Gibbons R.J., Balady G.J., Timothy B.J., et al. ACC/AHA 2002 guideline update for exercise testing: summary article. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1997 Exercise Testing Guidelines). J Am Coll Cardiol 2002, 40(8):1531-1540.
32. Lin C.K., Lin C.C. Work of breathing and respiratory drive in obesity. Respirology 2012, 17(3):402-411.
33. Sood A. Altered resting and exercise respiratory physiology in obesity. Clin Chest Med 2009;30(3):445-54, vii.
34. Hamm L.F., Wenger N.K., Arena R., et al. Cardiac rehabilitation and cardiovascular disability: role in assessment and improving functional capacity: a position statement from the American Association of Cardiovascular and Pulmonary Rehabilitation. J Cardiopulm Rehabil Prev 2013, 33(1):1-11.
35. Kodama S., Saito K., Tanaka S., et al. Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis. JAMA 2009, 301(19):2024-2035.
36. Myers J., Prakash M., Froelicher V., Do D., Partington S., Atwood J.E. Exercise capacity and mortality among men referred for exercise testing. N Engl J Med 2002, 346(11):793-801.
37. Lipinski M.J., Vetrovec G.W., Gorelik D., Froelicher V.F. The importance of heart rate recovery in patients with heart failure or left ventricular systolic dysfunction. J Card Fail 2005, 11(8):624-630.
38. Lauer M., Froelicher E.S., Williams M., Kligfield P. Exercise testing in asymptomatic adults: a statement for professionals from the American Heart Association Council on Clinical Cardiology, Subcommittee on Exercise, Cardiac rehabilitAtion, and Prevention. Circulation 2005, 112(5):771-776.
39. Arena R., Lavie C.J. Excess body weigth and cornoary artery disease-associated risks, the obesity paradox, and implications for cardiac rehabilitation. US Cardiology 2011, 8(2):88-93.
40. Arena R., Lavie C.J. The obesity paradox and outcome in heart failure: is excess bodyweight truly protective?. Future Cardiol 2010, 6(1):1-6.
41. Fonarow G.C., Srikanthan P., Costanzo M.R., Cintron G.B., Lopatin M. An obesity paradox in acute heart failure: analysis of body mass index and inhospital mortality for 108,927 patients in the Acute Decompensated Heart Failure National Registry. Am Heart J 2007, 153(1):74-81.
42. McAuley P.A., Kokkinos P.F., Oliveira R.B., Emerson B.T., Myers J.N. Obesity paradox and cardiorespiratory fitness in 12,417 male veterans aged 40 to 70years. Mayo Clin Proc 2010, 85(2):115-121.
43. Lavie C.J., Cahalin L.P., Chase P., et al. The impact of cardiorespiratory fitness on the obesity paradox in patients with heart failure. Mayo Clin Proc 2013, 88(3):251-258.
44. Hakala K., Mustajoki P., Aittomaki J., Sovijarvi A. Improved gas exchange during exercise after weight loss in morbid obesity. Clin Physiol 1996, 16(3):229-238.
45. Brinkworth G.D., Noakes M., Buckley J.D., Clifton P.M. Weight loss improves heart rate recovery in overweight and obese men with features of the metabolic syndrome. Am Heart J 2006, 152(4):693-696.
46. Nagashima J., Musha H., Takada H., et al. Three-month exercise and weight loss program improves heart rate recovery in obese persons along with cardiopulmonary function. J Cardiol 2010, 56(1):79-84.
47. Fletcher G.F., Balady G.J., Amsterdam E.A., et al. Exercise standards for testing and training: a statement for healthcare professionals from the American Heart Association. Circulation 2001, 104(14):1694-1740.
48. Scano G., Stendardi L., Bruni G.I. The respiratory muscles in eucapnic obesity: their role in dyspnea. Respir Med 2009, 103(9):1276-1285.
49. Collet F., Mallart A., Bervar J.F., et al. Physiologic correlates of dyspnea in patients with morbid obesity. Int J Obes (Lond) 2007, 31(4):700-706.
50. Rochester D.F., Enson Y. Current concepts in the pathogenesis of the obesity-hypoventilation syndrome. Mechanical and circulatory factors. Am J Med 1974, 57(3):402-420.
51. Ora J., Laveneziana P., Wadell K., Preston M., Webb K.A., O'Donnell D.E. Effect of obesity on respiratory mechanics during rest and exercise in COPD. J Appl Physiol 2011, 111(1):10-19.
52. De L.A., Petrone-De L.P., Sasso G.F., Carbonelli M.G., Rossi P., Brancati A. Effects of weight loss on body composition and pulmonary function. Respiration 1999, 66(5):407-412.
53. Pistelli F., Bottai M., Carrozzi L., et al. Changes in obesity status and lung function decline in a general population sample. Respir Med 2008, 102(5):674-680.
54. Sahebjami H. Dyspnea in obese healthy men. Chest 1998, 114(5):1373-1377.
55. Black L.F., Hyatt R.E. Maximal respiratory pressures: normal values and relationship to age and sex. Am Rev Respir Dis 1969, 99(5):696-702.
56. Nickerson B.G., Keens T.G. Measuring ventilatory muscle endurance in humans as sustainable inspiratory pressure. J Appl Physiol 1982, 52(3):768-772.
57. Martyn J.B., Moreno R.H., Pare P.D., Pardy R.L. Measurement of inspiratory muscle performance with incremental threshold loading. Am Rev Respir Dis 1987, 135(4):919-923.
58. Weiner P., Waizman J., Weiner M., Rabner M., Magadle R., Zamir D. Influence of excessive weight loss after gastroplasty for morbid obesity on respiratory muscle performance. Thorax 1998, 53(1):39-42.
59. Sampson M.G., Grassino K. Neuromechanical properties in obese patients during carbon dioxide rebreathing. Am J Med 1983, 75(1):81-90.
60. Chlif M., Keochkerian D., Choquet D., Vaidie A., Ahmaidi S. Effects of obesity on breathing pattern, ventilatory neural drive and mechanics. Respir Physiol Neurobiol 2009, 168(3):198-202.
61. Casali C.C., Pereira A.P., Martinez J.A., de Souza H.C., Gastaldi A.C. Effects of inspiratory muscle training on muscular and pulmonary function after bariatric surgery in obese patients. Obes Surg 2011, 21(9):1389-1394.
62. Barbalho-Moulim M.C., Miguel G.P., Forti E.M., Campos F.A., Costa D. Effects of preoperative inspiratory muscle training in obese women undergoing open bariatric surgery: respiratory muscle strength, lung volumes, and diaphragmatic excursion. Clinics (Sao Paulo) 2011, 66(10):1721-1727.
63. Tenorio L.H., Santos A.C., Camara Neto J.B., et al. The influence of inspiratory muscle training on diaphragmatic mobility, pulmonary function and maximum respiratory pressures in morbidly obese individuals: a pilot study. Disabil Rehabil 2013.
64. Frank I., Briggs R., Spengler C.M. Respiratory muscles, exercise performance, and health in overweight and obese subjects. Med Sci Sports Exerc 2011, 43(4):714-727.
65. Villiot-Danger J.C., Villiot-Danger E., Borel J.C., Pepin J.L., Wuyam B., Verges S. Respiratory muscle endurance training in obese patients. Int J Obes (Lond) 2011, 35(5):692-699.
66. Kelly T.M., Jensen R.L., Elliott C.G., Crapo R.O. Maximum respiratory pressures in morbidly obese subjects. Respiration 1988, 54(2):73-77.
67. Chlif M., Keochkerian D., Feki Y., Vaidie A., Choquet D., Ahmaidi S. Inspiratory muscle activity during incremental exercise in obese men. Int J Obes (Lond) 2007, 31(9):1456-1463.
68. Roger V.L., Go A.S., Lloyd-Jones D.M., et al. Heart disease and stroke statistics-2012 update: a report from the American Heart Association. Circulation 2012, 125(1):e2-e220.