A supra-cellular model for coupling of bone resorption to formation during remodeling: Lessons from two bone resorption inhibitors affecting bone formation differently

Biochemical and Biophysical Research Communications

Volumn 443, Issue 2, 2014, Pages 694-699

  Jensen, Pia Rosgaard ^a   Andersen, Thomas Levin ^a   Pennypacker, Brenda L ^b   Duong, Le T ^b   Engelholm, Lars H ^c   Delaissé, Jean Marie ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b MERCK RESEARCH LABORATORIES   (United States)

^c FINSEN LABORATORY   (Denmark)

Author keywords

Bisphosphonates; Bone remodeling compartment canopy; Cathepsin K inhibitor; Coupling; Osteoclast anabolics; Osteoprogenitors

Indexed keywords

ALENDRONIC ACID; COLLAGEN; ODANACATIB;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE REMODELING; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG RESPONSE; EXPERIMENTAL RABBIT; FEMALE; LUMBAR VERTEBRA; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; OVARIECTOMY; PRIORITY JOURNAL; RECEPTOR BINDING;

ORYCTOLAGUS CUNICULUS;

BISPHOSPHONATES; BONE REMODELING COMPARTMENT CANOPY; CATHEPSIN K INHIBITOR; COUPLING; OSTEOCLAST ANABOLICS; OSTEOPROGENITORS;

ANIMALS; BONE MATRIX; BONE REMODELING; BONE RESORPTION; COMPUTER SIMULATION; MODELS, BIOLOGICAL; OSTEOCLASTS; RABBITS; SPINE;

EID: 84892434966     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.12.036     Document Type: Article

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