Lipopolyplexes comprising imidazole/imidazolium lipophosphoramidate, histidinylated polyethyleneimine and siRNA as efficient formulation for siRNA transfection

International Journal of Pharmaceutics

Volumn 460, Issue 1-2, 2014, Pages 264-272

  Gonçalves, Cristine ^a   Berchel, Mathieu ^b   Gosselin, Marie Pierre ^a   Malard, Virginie ^a   Cheradame, Hervé ^c   Jaffrès, Paul Alain ^b   Guégan, Philippe ^d   Pichon, Chantal ^a   Midoux, Patrick ^a  

^a UNIVERSITÉ D'ORLÉANS   (France)

^b UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

^c UNIVERSITÉ D EVRY VAL D ESSONNE   (France)

^d SORBONNE UNIVERSITÉ   (France)

Author keywords

Histidine; Liposomes; Polymer; RNA; RNA interference; Transfection

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; ENHANCED GREEN FLUORESCENT PROTEIN; HISTIDINE; IMIDAZOLE; LIPOFECTAMINE; LUCIFERASE; MESSENGER RNA; O,O DIOLEYL N [3N (N METHYLIMIDAZOLIUM IODIDE)PROPYLENE]PHOSPHORAMIDATE; O,O DIOLEYL N HISTAMINE PHOSPHORAMIDATE; PHOSPHORAMIDIC ACID DERIVATIVE; POLYETHYLENEIMINE; POLYMER; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG FORMULATION; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HELA CELL; LIPOSOMAL GENE DELIVERY SYSTEM; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; ZETA POTENTIAL;

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE; DC-CHOL; DIPALMITOYL-PHOSPHATIDYL-CHOLINE; DOCSPER; DOPE; DOTAP; DOTMA; DPPC; DPPG; DSAA; DSPE-PEG2000; DSPE-PEG2000-NH(2); HISTIDINE; L-PHOSPHATIDYL-GLYCEROL; LIPOSOMES; N,N-DISTEARYL-N-METHYL-N-2-(N′-ARGINYL)AMINOETHYL AMMONIUM CHLORIDE; N-POLYETHYLENEGLYCOL (M.W. 2000) - DISTEAROYLPHOSPHATIDYLETHANOLAMINE; N-[1(2,3-DIOLEOYLOXY)PROPYL]-N,N,N-TRIMETHYLAMONIUM METHYL SULFATE; N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHLYLAMMONIUM CHLORIDE; PC; PHOSPHATIDYL-CHOLINE.; POLYETHYLENEGLYCOL (M.W. 2000) - DISTEAROYLPHOSPHATIDYLETHANOLAMINE; POLYMER; RNA; RNA INTERFERENCE; TRANSFECTION; [1,3-DIOLEOYLOXY-2-(N(5)-CARBAMOYL-SPERMINE)-PROPANE]; [N-(N′,N′-DIMETHYLAMINOETHANE)-CARBAMOYL] CHOLESTEROL HYDROCHLORIDE;

CELL LINE, TUMOR; GREEN FLUORESCENT PROTEINS; HELA CELLS; HISTIDINE; HUMANS; IMIDAZOLES; LIPOSOMES; LUCIFERASES; MELANOMA, EXPERIMENTAL; POLYETHYLENEIMINE; POLYMERS; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84892433377     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.11.005     Document Type: Article

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