ZIC1 is silenced and has tumor suppressor function in malignant pleural mesothelioma

Journal of Thoracic Oncology

Volumn 8, Issue 10, 2013, Pages 1317-1328

  Cheng, Yuen Yee ^a   Kirschner, Michaela B ^a   Cheng, Ngan Ching ^a   Gattani, Sumedha ^a   Klebe, Sonja ^b   Edelman, J James B ^c,d   Vallely, Michael P ^c,d   McCaughan, Brian C ^c,d   Jin, Hong Chuan ^e   Van Zandwijk, Nico ^a   Reid, Glen ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b FLINDERS MEDICAL CENTRE   (Australia)

^c ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

^e ZHEJIANG UNIVERSITY   (China)

Author keywords

Epigenetic gene silencing; Malignant mesothelioma; Methylation; MiRNA; ZIC1

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; MICRORNA; MICRORNA 23A; MICRORNA 27A; PROTEIN ZIC 1; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ARTICLE; CANCER INHIBITION; CANCER PATIENT; CANCER SURVIVAL; CELL INVASION; CHROMATIN IMMUNOPRECIPITATION; COLONY FORMATION; COMPARATIVE STUDY; CONTROLLED STUDY; DNA METHYLATION; GENE SILENCING; HUMAN; HUMAN CELL; MESOTHELIUM CELL; PLEURA MESOTHELIOMA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN METHYLATION; UPREGULATION;

ADULT; AGED; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; DNA METHYLATION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; FOLLOW-UP STUDIES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOENZYME TECHNIQUES; LUNG NEOPLASMS; MALE; MESOTHELIOMA; MICRORNAS; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLEURAL NEOPLASMS; PROGNOSIS; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SURVIVAL RATE; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 84892403139     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0b013e3182a0840a     Document Type: Article

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