In silico, in vitro and in vivo analysis of binding affinity between N and C-domains of clostridium perfringens alpha toxin

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Uppalapati, Siva Ramakrishna ^a   Kingston, Joseph Jeyabalaji ^a   Qureshi, Insaf Ahmed ^b   Murali, Harishchandra Sripathy ^a   Batra, Harsh Vardhan ^a  

^a DEFENCE FOOD RESEARCH LABORATORY   (India)

^b UNIVERSITY OF HYDERABAD   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CLOSTRIDIUM TOXIN; PHOSPHOLIPASE C;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BIOINFORMATICS; CARBOXY TERMINAL SEQUENCE; CELL KINETICS; CLOSTRIDIUM PERFRINGENS; COMPUTER MODEL; CONTROLLED STUDY; CYTOLYSIS; ENZYME BINDING; ENZYME STABILITY; ERYTHROCYTE; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MUSCLE NECROSIS; NONHUMAN; PREDICTION; PROTEIN DOMAIN; PROTEIN INTERACTION; STATIC ELECTRICITY;

ANIMALS; BACTERIAL TOXINS; BINDING SITES; CALCIUM-BINDING PROTEINS; CLOSTRIDIUM PERFRINGENS; ERYTHROCYTES; FEMALE; GENE EXPRESSION; HEMOLYSIS; INJECTIONS, INTRAMUSCULAR; MICE; MICE, INBRED BALB C; MOLECULAR DYNAMICS SIMULATION; MUSCLE, SKELETAL; NECROSIS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; STATIC ELECTRICITY; TYPE C PHOSPHOLIPASES;

EID: 84892389788     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0082024     Document Type: Article

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