메뉴 건너뛰기




Volumn 27, Issue 6, 2013, Pages 581-590

Renal effects of levosimendan: A consensus report

(25)  Yilmaz, Mehmet B a   Grossini, Elena b   Silva Cardoso, José C c   Édes, István d   Fedele, Francesco e   Pollesello, Piero f   Kivikko, Matti f   Harjola, Veli Pekka g   Hasslacher, Julia h   Mebazaa, Alexandre i   Morelli, Andrea e   Le Noble, Jos j   Oldner, Anders k   Erroz, Ignacio Oulego l   Parissis, John T m   Parkhomenko, Alexander n   Poelzl, Gerhard o   Rehberg, Sebastian p   Ricksten, Sven Erik q   Rodríguez Fernández, Luís M l   more..


Author keywords

Levosimendan; Renal dysfunction

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CREATININE; FENOLDOPAM; HTK SOLUTION; ILOPROST; LEVOSIMENDAN; MILRINONE; N ACETYL BETA GLUCOSAMINIDASE; NORADRENALIN; PIMOBENDAN; PLACEBO; UREA; VASOPRESSIN;

EID: 84892373432     PISSN: 09203206     EISSN: 15737241     Source Type: Journal    
DOI: 10.1007/s10557-013-6485-6     Document Type: Review
Times cited : (67)

References (52)
  • 2
    • 84875882097 scopus 로고    scopus 로고
    • Karoui a [acute renal failure after cardiac surgery: Evaluation of the RIFLE criteria]
    • Kallel S, Triki Z, Abdenadher M, Frikha I, Jemel A. Karoui a [acute renal failure after cardiac surgery: evaluation of the RIFLE criteria]. Nephrol Ther. 2013;9:108-14.
    • (2013) Nephrol Ther. , vol.9 , pp. 108-114
    • Kallel, S.1    Triki, Z.2    Abdenadher, M.3    Frikha, I.4    Jemel, A.5
  • 3
    • 42449114943 scopus 로고    scopus 로고
    • Acute renal failure in patients with severe sepsis and septic shock - A significant independent risk factor for mortality: Results from the German Prevalence Study
    • Oppert M, Engel C, Brunkhorst F-M, Bogatsch H, Reinhart K, Frei U, et al. Acute renal failure in patients with severe sepsis and septic shock-a significant independent risk factor for mortality: results from the German Prevalence Study. Nephrol Dial Transplant. 2008;23:904-9.
    • (2008) Nephrol Dial Transplant. , vol.23 , pp. 904-909
    • Oppert, M.1    Engel, C.2    Brunkhorst, F.-M.3    Bogatsch, H.4    Reinhart, K.5    Frei, U.6
  • 4
  • 6
    • 84864990939 scopus 로고    scopus 로고
    • Levosimendan: Molecular mechanisms and clinical implications: Consensus of experts on the mechanisms of action of levosimendan
    • Papp Z, Edes I, Fruhwald S, De Hert SG, Salmenpera M, Leppikangas H, et al. Levosimendan: molecular mechanisms and clinical implications: consensus of experts on the mechanisms of action of levosimendan. Int J Cardiol. 2012;159:82-7.
    • (2012) Int J Cardiol. , vol.159 , pp. 82-87
    • Papp, Z.1    Edes, I.2    Fruhwald, S.3    De Hert, S.G.4    Salmenpera, M.5    Leppikangas, H.6
  • 7
  • 8
    • 67650364180 scopus 로고    scopus 로고
    • Effects of levosimendan on the energy balance: Preclinical and clinical evidence
    • Nieminen MS, Pollesello P, Vajda G, Papp Z. Effects of levosimendan on the energy balance: preclinical and clinical evidence. J Cardiovasc Pharmacol. 2009;53:302-10.
    • (2009) J Cardiovasc Pharmacol. , vol.53 , pp. 302-10
    • Nieminen, M.S.1    Pollesello, P.2    Vajda, G.3    Papp, Z.4
  • 9
    • 0037422531 scopus 로고    scopus 로고
    • Sustained hemodynamic effects of intravenous levosimendan
    • Kivikko M, Lehtonen L, Colucci WS. Sustained hemodynamic effects of intravenous levosimendan. Circulation. 2003;107:81-6.
    • (2003) Circulation. , vol.107 , pp. 81-86
    • Kivikko, M.1    Lehtonen, L.2    Colucci, W.S.3
  • 10
    • 0029788449 scopus 로고    scopus 로고
    • Influence of levosimendan, pimobendan, and milrinone on the regional distribution of cardiac output in anaesthetized dogs
    • Pagel PS, Hettrick DA, Warltier DC. Influence of levosimendan, pimobendan, and milrinone on the regional distribution of cardiac output in anaesthetized dogs. Br J Pharmacol. 1996;119:609-15.
    • (1996) Br J Pharmacol. , vol.119 , pp. 609-615
    • Pagel, P.S.1    Hettrick, D.A.2    Warltier, D.C.3
  • 11
    • 24144451071 scopus 로고    scopus 로고
    • Cardiac and renal effects of levosimendan, arginine vasopressin, and norepinephrine in lipopolysaccharide-treated rabbits
    • Faivre V, Kaskos H, Callebert J, Losser M-R,Milliez P, Bonnin P, et al. Cardiac and renal effects of levosimendan, arginine vasopressin, and norepinephrine in lipopolysaccharide-treated rabbits. Anesthesiology. 2005;103:514-21.
    • (2005) Anesthesiology. , vol.103 , pp. 514-521
    • Faivre, V.1    Kaskos, H.2    Callebert, J.3    Losser, M.-R.4    Milliez, P.5    Bonnin, P.6
  • 12
    • 0035174034 scopus 로고    scopus 로고
    • Effects of levosimendan, a novel inotropic calcium-sensitizing drug, in experimental septic shock
    • Oldner A, Konrad D,Weitzberg E, Rudehill A, Rossi P,Wanecek M. Effects of levosimendan, a novel inotropic calcium-sensitizing drug, in experimental septic shock. Crit Care Med. 2001;29:2185-93.
    • (2001) Crit Care Med. , vol.29 , pp. 2185-2193
    • Oldner, A.1    Konrad, D.2    Weitzberg, E.3    Rudehill, A.4    Rossi, P.5    Wanecek, M.6
  • 15
    • 77957236621 scopus 로고    scopus 로고
    • Effects of combined arginine vasopressin and levosimendan on organ function in ovine septic shock
    • Rehberg S, Ertmer C, Vincent J-L, Spiegel H-U, Kohler G, Erren M, et al. Effects of combined arginine vasopressin and levosimendan on organ function in ovine septic shock. Crit Care Med. 2010;38:2016-23.
    • (2010) Crit Care Med. , vol.38 , pp. 2016-2023
    • Rehberg, S.1    Ertmer, C.2    Vincent, J.-L.3    Spiegel, H.-U.4    Kohler, G.5    Erren, M.6
  • 16
    • 0002797219 scopus 로고    scopus 로고
    • Ischemia-reperfusion injury and the systemic inflammatory response syndrome
    • In: Grace PA, Mathie RT, editors, London: Blackwell Science
    • Neary P, Redmond HP. Ischemia-reperfusion injury and the systemic inflammatory response syndrome. In: Grace PA, Mathie RT, editors. Ischemia-reperfusion injury. London: Blackwell Science; 1999. p. 123-36.
    • (1999) Ischemia-Reperfusion Injury , pp. 123-136
    • Neary, P.1    Redmond, H.P.2
  • 17
    • 0036425596 scopus 로고    scopus 로고
    • Effects of trimetazidine on tissue damage in kidney after hindlimb ischemia-reperfusion
    • Sucu N, Unlu A, Tamer L, Aytacoglu B, Coskun B, Bilgin R, et al. Effects of trimetazidine on tissue damage in kidney after hindlimb ischemia-reperfusion. Pharmacol Res. 2002;46:345-9.
    • (2002) Pharmacol Res. , vol.46 , pp. 345-349
    • Sucu, N.1    Unlu, A.2    Tamer, L.3    Aytacoglu, B.4    Coskun, B.5    Bilgin, R.6
  • 19
    • 0033959417 scopus 로고    scopus 로고
    • Levosimendan, a new positive inotropic drug, decreases myocardial infarct size via activation of K(ATP) channels
    • Kersten JR, Montgomery MW, Pagel PS, Warltier DC. Levosimendan, a new positive inotropic drug, decreases myocardial infarct size via activation of K(ATP) channels. Anesth Analg. 2000;90:5-11.
    • (2000) Anesth Analg. , vol.90 , pp. 5-11
    • Kersten, J.R.1    Montgomery, M.W.2    Pagel, P.S.3    Warltier, D.C.4
  • 20
    • 79952491928 scopus 로고    scopus 로고
    • Levosimendan preserves the contractile responsiveness of hypoxic human myocardium via mitochondrial K(ATP) channel and potential pERK 1/2 activation
    • Soeding PF, Crack PJ, Wright CE, Angus JA, Royse CF. Levosimendan preserves the contractile responsiveness of hypoxic human myocardium via mitochondrial K(ATP) channel and potential pERK 1/2 activation. Eur J Pharmacol. 2011;655:59-66.
    • (2011) Eur J Pharmacol. , vol.655 , pp. 59-66
    • Soeding, P.F.1    Crack, P.J.2    Wright, C.E.3    Angus, J.A.4    Royse, C.F.5
  • 21
    • 23744462187 scopus 로고    scopus 로고
    • The Ca2+-sensitizer levosimendan improves oxidative damage, BNP and pro-inflammatory cytokine levels in patients with advanced decompensated heart failure in comparison to dobutamine
    • Avgeropoulou C, Andreadou I, Markantonis-Kyroudis S, Demopoulou M, Missovoulos P, Androulakis A, et al. The Ca2+-sensitizer levosimendan improves oxidative damage, BNP and pro-inflammatory cytokine levels in patients with advanced decompensated heart failure in comparison to dobutamine. Eur J Heart Fail. 2005;7:882-7.
    • (2005) Eur J Heart Fail. , vol.7 , pp. 882-887
    • Avgeropoulou, C.1    Andreadou, I.2    Markantonis-Kyroudis, S.3    Demopoulou, M.4    Missovoulos, P.5    Androulakis, A.6
  • 24
    • 70350627553 scopus 로고    scopus 로고
    • Effects of calcium sensitizer OR-1986 on a cardiovascular mortality and myocardial remodelling in hypertensive Dahl/Rapp rats
    • Louhelainen M, Merasto S, Finckenberg P, Vahtola E, Kaheinen P, Leskinen H, et al. Effects of calcium sensitizer OR-1986 on a cardiovascular mortality and myocardial remodelling in hypertensive Dahl/Rapp rats. J Physiol Pharmacol. 2009;60:41-7.
    • (2009) J Physiol Pharmacol. , vol.60 , pp. 41-47
    • Louhelainen, M.1    Merasto, S.2    Finckenberg, P.3    Vahtola, E.4    Kaheinen, P.5    Leskinen, H.6
  • 25
    • 0037142946 scopus 로고    scopus 로고
    • Efficacy and safety of intravenous levosimendan comparedwith dobutamine in severe low-output heart failure (the LIDO study): A randomised double-blind trial
    • Follath F, Cleland JGF, Just H, Papp JGY, Scholz H, Peuhkurinen K, et al. Efficacy and safety of intravenous levosimendan comparedwith dobutamine in severe low-output heart failure (the LIDO study): a randomised double-blind trial. Lancet. 2002;360:196-202.
    • (2002) Lancet. , vol.360 , pp. 196-202
    • Follath, F.1    Cleland, J.G.F.2    Just, H.3    Papp, J.G.Y.4    Scholz, H.5    Peuhkurinen, K.6
  • 27
    • 34547442389 scopus 로고    scopus 로고
    • Levosimendan improves renal function in patients with advanced chronic heart failure awaiting cardiac transplantation
    • Zemljic G, Bunc M, Yazdanbakhsh AP, Vrtovec B. Levosimendan improves renal function in patients with advanced chronic heart failure awaiting cardiac transplantation. J Card Fail. 2007;13:417-21.
    • (2007) J Card Fail. , vol.13 , pp. 417-421
    • Zemljic, G.1    Bunc, M.2    Yazdanbakhsh, A.P.3    Vrtovec, B.4
  • 28
    • 36849013485 scopus 로고    scopus 로고
    • Levosimendan improves renal function in patients with acute decompensated heart failure: Comparison with dobutamine
    • Yilmaz MB, Yalta K, Yontar C, Karadas F, Erdem A, Turgut OO, et al. Levosimendan improves renal function in patients with acute decompensated heart failure: comparison with dobutamine. Cardiovasc Drugs Ther. 2007;21:431-5.
    • (2007) Cardiovasc Drugs Ther. , vol.21 , pp. 431-435
    • Yilmaz, M.B.1    Yalta, K.2    Yontar, C.3    Karadas, F.4    Erdem, A.5    Turgut, O.O.6
  • 29
    • 59049083156 scopus 로고    scopus 로고
    • Comparative effects of levosimendan and dobutamine on right ventricular function in patients with biventricular heart failure
    • Yilmaz MB, Yontar C, Erdem A, Karadas F, Yalta K, Turgut OO, et al. Comparative effects of levosimendan and dobutamine on right ventricular function in patients with biventricular heart failure. Heart Vessels. 2009;24:16-21.
    • (2009) Heart Vessels , vol.24 , pp. 16-21
    • Yilmaz, M.B.1    Yontar, C.2    Erdem, A.3    Karadas, F.4    Yalta, K.5    Turgut, O.O.6
  • 30
    • 84866142081 scopus 로고    scopus 로고
    • Effect of levosimendan in patients with severe systolic heart failure and worsening renal function
    • Zorlu A, Yucel H, Yontar OC, Karahan O, Tandogan I, Katrancioglu N, et al. Effect of levosimendan in patients with severe systolic heart failure and worsening renal function. Arq Bras Cardiol. 2012;98:537-43.
    • (2012) Arq Bras Cardiol. , vol.98 , pp. 537-543
    • Zorlu, A.1    Yucel, H.2    Yontar, O.C.3    Karahan, O.4    Tandogan, I.5    Katrancioglu, N.6
  • 31
    • 84996575043 scopus 로고    scopus 로고
    • 475 Effects of Levosimendan on renal function and renal hemodynamic parameters in patients with acute heart failure
    • Caira C, Brasolin B, Maestrini V, Scardala R, Orvieto G, Mancone M, et al. 475 Effects of Levosimendan on renal function and renal hemodynamic parameters in patients with acute heart failure. Eur J Heart Fail Suppl. 2007;6:103.
    • (2007) Eur J Heart Fail Suppl. , vol.6 , pp. 103
    • Caira, C.1    Brasolin, B.2    Maestrini, V.3    Scardala, R.4    Orvieto, G.5    Mancone, M.6
  • 33
    • 84892371214 scopus 로고    scopus 로고
    • Effects of levosimendan on renal blood flow, glomerular filtration rate, renal oxygen consumption and oxygenation after cardiac surgery: A randomized controlled study
    • In press
    • Bragadottir G, Redfors B, Ricksten SE. Effects of levosimendan on renal blood flow, glomerular filtration rate, renal oxygen consumption and oxygenation after cardiac surgery: a randomized controlled study. Crit Care Med, In press.
    • Crit Care Med
    • Bragadottir, G.1    Redfors, B.2    Ricksten, S.E.3
  • 34
    • 58249132859 scopus 로고    scopus 로고
    • Levosimendan facilitates weaning from cardiopulmonary bypass in patients undergoing coronary artery bypass grafting with impaired left ventricular function
    • Eriksson HI, Jalonen JR, Heikkinen LO, KivikkoM, Laine M, Leino KA, et al. Levosimendan facilitates weaning from cardiopulmonary bypass in patients undergoing coronary artery bypass grafting with impaired left ventricular function. Ann Thorac Surg. 2009;87:448-54.
    • (2009) Ann Thorac Surg. , vol.87 , pp. 448-54
    • Eriksson, H.I.1    Jalonen, J.R.2    Heikkinen, L.O.3    Kivikko, M.4    Laine, M.5    Leino, K.A.6
  • 36
    • 33646939018 scopus 로고    scopus 로고
    • Levosimendan or milrinone in the type 2 diabetic patient with low ejection fraction undergoing elective coronary artery surgery
    • Al-Shawaf E, Ayed A, Vislocky I, Radomir B, Dehrab N, Tarazi R. Levosimendan or milrinone in the type 2 diabetic patient with low ejection fraction undergoing elective coronary artery surgery. J Cardiothorac Vasc Anesth. 2006;20:353-7.
    • (2006) J Cardiothorac Vasc Anesth. , vol.20 , pp. 353-357
    • Al-Shawaf, E.1    Ayed, A.2    Vislocky, I.3    Radomir, B.4    Dehrab, N.5    Tarazi, R.6
  • 39
    • 46449138711 scopus 로고    scopus 로고
    • The calciumsensitizer levosimendan gives superior results to dobutamine in postoperative low cardiac output syndrome
    • Levin RL, Degrange MA, Porcile R, Salvagio F, Blanco N, Botbol AL, et al. [The calciumsensitizer levosimendan gives superior results to dobutamine in postoperative low cardiac output syndrome]. Rev Esp Cardiol. 2008;61:471-9.
    • (2008) Rev Esp Cardiol. , vol.61 , pp. 471-479
    • Levin, R.L.1    Degrange, M.A.2    Porcile, R.3    Salvagio, F.4    Blanco, N.5    Botbol, A.L.6
  • 40
    • 21044443575 scopus 로고    scopus 로고
    • Effects of levosimendan on systemic and regional hemodynamics in septic myocardial depression
    • Morelli A, De Castro S, Teboul J-L, Singer M, Rocco M, Conti G, et al. Effects of levosimendan on systemic and regional hemodynamics in septic myocardial depression. Intensive Care Med. 2005;31:638-44.
    • (2005) Intensive Care Med. , vol.31 , pp. 638-644
    • Morelli, A.1    De Castro, S.2    Teboul, J.-L.3    Singer, M.4    Rocco, M.5    Conti, G.6
  • 41
    • 70450171316 scopus 로고    scopus 로고
    • Reducing the risk of major elective non-cardiac surgery: Is there a role for levosimendan in the preoperative optimization of cardiac function?
    • Morelli A, Ertmer C, Pietropaoli P,WestphalM. Reducing the risk of major elective non-cardiac surgery: is there a role for levosimendan in the preoperative optimization of cardiac function? Curr Drug Targets. 2009;10:863-71.
    • (2009) Curr Drug Targets. , vol.10 , pp. 863-871
    • Morelli, A.1    Ertmer, C.2    Pietropaoli, P.3    Westphal, M.4
  • 42
    • 59649087169 scopus 로고    scopus 로고
    • Increased central venous pressure is associated with impaired renal function and mortality in a broad spectrum of patients with cardiovascular disease
    • Damman K, van Deursen VM, Navis G, Voors AA, van Veldhuisen DJ, Hillege HL. Increased central venous pressure is associated with impaired renal function and mortality in a broad spectrum of patients with cardiovascular disease. J Am Coll Cardiol. 2009;53:582-8.
    • (2009) J Am Coll Cardiol. , vol.53 , pp. 582-588
    • Damman, K.1    Van Deursen, V.M.2    Navis, G.3    Voors, A.A.4    Van Veldhuisen, D.J.5    Hillege, H.L.6
  • 43
    • 33751160138 scopus 로고    scopus 로고
    • Effects of levosimendan on right ventricular function in patients with advanced heart failure
    • Parissis JT, Paraskevaidis I, Bistola V, Farmakis D, Panou F, Kourea K, et al. Effects of levosimendan on right ventricular function in patients with advanced heart failure. Am J Cardiol. 2006;98:1489-92.
    • (2006) Am J Cardiol. , vol.98 , pp. 1489-1492
    • Parissis, J.T.1    Paraskevaidis, I.2    Bistola, V.3    Farmakis, D.4    Panou, F.5    Kourea, K.6
  • 44
    • 51349149595 scopus 로고    scopus 로고
    • Safety and effectiveness of levosimendan in patients with predominant right heart failure
    • Poelzl G, Zwick RH, Grander W, Metzler B, Jonetzko P, Frick M, et al. Safety and effectiveness of levosimendan in patients with predominant right heart failure. Herz. 2008;33:368-73.
    • (2008) Herz. , vol.33 , pp. 368-373
    • Poelzl, G.1    Zwick, R.H.2    Grander, W.3    Metzler, B.4    Jonetzko, P.5    Frick, M.6
  • 45
    • 73349086240 scopus 로고    scopus 로고
    • Right ventricular function in myocardial infarction complicated by cardiogenic shock: Improvement with levosimendan
    • Russ MA, Prondzinsky R, Carter JM, Schlitt A, Ebelt H, Schmidt H, et al. Right ventricular function in myocardial infarction complicated by cardiogenic shock: improvement with levosimendan. Crit Care Med. 2009;37:3017-23.
    • (2009) Crit Care Med. , vol.37 , pp. 3017-3023
    • Russ, M.A.1    Prondzinsky, R.2    Carter, J.M.3    Schlitt, A.4    Ebelt, H.5    Schmidt, H.6
  • 46
    • 0026666788 scopus 로고
    • Intracellular ATP can regulate afferent arteriolar tone via ATPsensitive K+channels in the rabbit
    • Lorenz JN, Schnermann J, Brosius FC, Briggs JP, Furspan PB. Intracellular ATP can regulate afferent arteriolar tone via ATPsensitive K+channels in the rabbit. J Clin Invest. 1992;90:733-40.
    • (1992) J Clin Invest. , vol.90 , pp. 733-740
    • Lorenz, J.N.1    Schnermann, J.2    Brosius, F.C.3    Briggs, J.P.4    Furspan, P.B.5
  • 48
    • 0022995815 scopus 로고
    • A mechanism by which atrial natriuretic factor mediates its glomerular actions
    • Appel RG, Wang J, Simonson MS, Dunn MJ. A mechanism by which atrial natriuretic factor mediates its glomerular actions. Am J Physiol. 1986;251:1036-42.
    • (1986) Am J Physiol. , vol.251 , pp. 1036-1042
    • Appel, R.G.1    Wang, J.2    Simonson, M.S.3    Dunn, M.J.4
  • 49
    • 84885020830 scopus 로고    scopus 로고
    • Peri-operative interventions, but not inflammatory mediators, increase risk of acute kidney injury after cardiac surgery: A prospective cohort study
    • Morgan CJ, Gill PJ, Lam S, Joffe AR. Peri-operative interventions, but not inflammatory mediators, increase risk of acute kidney injury after cardiac surgery: a prospective cohort study. Intensive CareMed. 2013;39:934-41.
    • (2013) Intensive Care Med. , vol.39 , pp. 934-941
    • Morgan, C.J.1    Gill, P.J.2    Lam, S.3    Joffe, A.R.4
  • 52
    • 79960189784 scopus 로고    scopus 로고
    • Levosimendan inhibits release of reactive oxygen species in polymorphonuclear leukocytes in vitro and in patients with acute heart failure and septic shock: A prospective observational study
    • Hasslacher J, Bijuklic K, Bertocchi C, Kountchev J, Bellmann R, Dunzendorfer S, et al. Levosimendan inhibits release of reactive oxygen species in polymorphonuclear leukocytes in vitro and in patients with acute heart failure and septic shock: a prospective observational study. Crit Care. 2011;15:R166.
    • (2011) Crit Care , vol.15
    • Hasslacher, J.1    Bijuklic, K.2    Bertocchi, C.3    Kountchev, J.4    Bellmann, R.5    Dunzendorfer, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.