Clinical false-positive drug test results

Handbook of Drug Monitoring Methods: Therapeutics and Drugs of Abuse

Volumn , Issue , 2008, Pages 395-406

  Kwong, Tai C ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Amphetamine; AQ1 opiate; cocaine; false positive; GC MS; marijuana

Indexed keywords

EID: 84892279976     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-59745-031-7_21     Document Type: Chapter

References (37)

1. Magnani B. Concentrations of compounds that produce positive results. In: Shaw L, Kwong T, eds. The Clinical Toxicology Laboratory, Contemporary Practice of Poisoning Evaluation. Washington, DC: AACC Press, 2001:482-497.
2. Green KB, Isenschmid DS. Medical review officer interpretation of urine drug test results. In: Liu RH, Goldberger B, eds. Handbook of Workplace Drug Testing. Washington, DC: AACC Press, 1995:321-354.
3. Fitzgerald RL, Ramos JM, Jr, Bogema SC, Poklis A. Resolution of methamphetamine stereoisomers in urine drug testing: urinary excretion of R(-)-methamphetamine following use of nasal inhalers. J Anal Toxicol 1988;12:255-259.
4. Cody JT. Determination of methamphetamine enantiomer ratios in urine by gas chromatography-mass spectrometry. J Chromatogr 1992;580:77-95.
5. Cody JT. Important issues in testing of methamphetamine enantiomer ratios in urine by gas chromatography-mass spectrometry. In: Liu RH, Goldberger B, eds. Handbook of Workplace Drug Testing. Washington, DC: AACC Press, 1995:239-288.
6. Department of Health and Human Services, Substance Abuse and Mental Health Services Administration. Medical Review Officer Manual for Federal Agency Workplace Drug Testing Programs. http://dwp. samhsa. gov/DrugTesting/Level-1- Pages/HHS%20MRO%20Manual%20(Effective% 20November%201,%202004). aspx. Accessed 11/05/2006.
7. Mahmood I. Clinical pharmacokinetics and pharmacodynamics of selegiline. An update. Clin Pharmacokinet 1997;33:91-102.
8. Cody JT, Valteria S. Amphetamine, clobenzorex, and 4-hydroxyclobenzorex levels following multidose administration of clobenzorex. J Anal Toxicol 2001;25:158-165.
9. Patrinely JR, Cruz OA, Reyna GS. The use of cocaine as an anesthetic in lacrimal surgery. J Anal Toxicol 1994;18:54-56.
10. Bralliar BB, Skarf B, Owens JB. Ophthalmic use of cocaine and the urine test for benzoylecgonine. N Engl J Med 1989;320:1757.
11. Altieri M, Bogema SC, Schwartz RH. TAC topical anesthesia produces positive urine tests for cocaine. Ann Emerg Med 1990;19:577-579.
12. Siegel RK, ElSohly HN, Plowman T, Rury PM, Jones RT. Cocaine in herbal tea. JAMA 1986;255:40.
13. ElSohly MA, Standford DF, ElSohly HN. Coca tea and urinalysis for cocaine metabolites. J Anal Toxicol 1986;10:256.
14. Jackson GF, Saddy JJ, Poklis A. Urinary excretion of benzoylecgonine following ingestion of Health Inca Tea. Forensic Sci Int 1991;49:57-64.
15. Turner M, McCrory P, Johnston A. Time for tea anyone? Br J Sports Med 2005;39:e37.
16. Cone E, Yousefnejad D, Hillsgrove MJ, Holicky B, Darwin WD. Passive inhalation of cocaine. J Anal Toxicol 1995;19:399-411.
17. ElSohly MA, Dewit H, Wachtel SR, Feng S, Murphy T. -9- Tetrahydrocannabivarin as a marker for the ingestion of marijuana versus Marinol : results of a clinical study. J Anal Toxicol 2001;25:565-571.
18. Huestis MA, Cone E. Drug test findings resulting from unconventional drug exposure. In: Liu RH, Goldberger B, eds. Handbook of Workplace Drug Testing. Washington, DC: AACC Press, 1995:289-320.
19. Cone E, Johnson RE, Darwin WD, Yousefnejad D, Mell LD, Paul BD. Passive inhalation of marijuana smoke: urinalysis and room air level of delta-9-tetrahydrocannabinol. J Anal Toxicol 1987;11:89-96.
20. Mule SJ, Casella GA. Active and realistic passive marijuana exposure tested by three immunoassays and GC/MS in urine. J Anal Toxicol 1988;12:113-116.
21. Niedbala S, Karodos K, Salamone S, Fritch D, Bronsgeest M, Cone EJ. Passive cannabis smoke exposure and oral fluid testing. J Anal Toxicol 2004;28:546-552.
22. Niedbala RS, Karodos KW, Fritch DF, Kunsman KP, Blum KA, Newland GA, Waga J, Kurtz L, Bronsgeest M, Cone EJ. Passive cannabis smoke exposure and oral fluid testing II: two studies of extreme cannabis smoke exposure in a motor vehicle. J Anal Toxicol 2005;29:607-615.
23. Alt A, Reinhardt G. Positive cannabis results in urine and blood samples after ingestion of hemp food products. J Anal Toxicol 1998;22:80-81.
24. Costantino A, Schwartz RH, Kaplan P. Hemp oil ingestion causes positive urine tests for -9-tetrahydrocannabinol carboxylic acid. J Anal Toxicol 1997;21:482-485.
25. Fortner N, Fogerson R, Lindman D, Iversen T, Armbruster D. Marijuana-positive urine test results from consumption of hemp seeds in food products. J Anal Toxicol 1997;21:476-481.
26. Struempler RE, Nelson G, Urry FM. A positive cannabinoids workplace drug test following ingestion of commercially available hemp seed oil. J Anal Toxicol 1997;21:283-285.
27. Leson G, Pless Petra, Grotenhermen F, Kalant H, ElSohly MA. Evaluating the impact of hemp food consumption on workplace drug tests. J Anal Toxicol 2001;25:691-698.
28. Gustafson RA, Levine B, Stout PR, Klette KL, George MP, Moolchan ET, Huestis MA. Urinary cannabinoid detection times after controlled oral administration of delta9-tetrahydrocannabinol. Clin Chem 2003;49:1114-1117.
29. ElSohly MA, Jones AB. Origin of morphine and codeine in biological fluids. In: Liu RH, Goldberger B, eds. Handbook of Workplace Drug Testing. Washington, DC: AACC Press, 1995:225-238.
30. Jackson GF, Saddy JJ, Poklis A. The determination of morphine in urine and oral fluid following ingestion of poppy seeds. J Anal Toxicol 2003; 27: 449-452.
31. Moeller MR, Hammer K, Engel O. Poppy seed consumption and toxicological analysis of blood and urine samples. Forensic Sci Int 2004;143:183-186.
32. Department of Health and Human Services, Substance Abuse and Mental Health Services Administration. Federal Register Notice Changing the Opiate Testing Cutoff Concentrations (effective December 1, 1998). http://dwp. samhsa. gov/FedPgms/Files/FR-Notice-Opiate-Testing- Cutoff-Concentrations. aspx. Accessed 11/05/2006.
33. ElSohly HN, ElSohly MA, Standford DF. Poppy seed ingestion of opiate urinalysis: a closer look. J Anal Toxicol 1990;14:308-310.
34. Cassella G, Wu AQH, Shaw BR, Hill DW. The analysis of thebaine in urine for the detection of poppy seed consumption. J Anal Toxicol 1997;21:376-383.
35. Meadway C, George S, Braithwaite R. Opiate concentrations following the ingestion of poppy seed products-evidence for poppy seed defense. Forensic Sci Int 1998;96:29-38.
36. Oyler JM, Cone E, Joseph RE, Jr, Huestis MA. Identification of hydrocodone in human urine following controlled codeine administration. J Anal Toxicol 2000;24:530-535.
37. Cone E, Heit HA, Caplan Y, Gourly D. Evidence of morphine metabolism to hydromorphone in pain patients chronically treated with morphine. J Anal Toxicol 2006;30:1-5.