Contralaterally transplanted human embryonic stem cell-derived neural precursor cells (ENStem-A) migrate and improve brain functions in stroke-damaged rats

Experimental and Molecular Medicine

Volumn 45, Issue 11, 2013, Pages

  Chang, Da Jeong ^a   Oh, Seung Hun ^b   Lee, Nayeon ^a   Choi, Chunggab ^a   Jeon, Iksoo ^a   Kim, Hyun Sook ^b   Shin, Dong Ah ^c   Lee, Seo Eun ^d   Kim, Daehong ^e   Song, Jihwan ^a,b  

^a CHA University   (South Korea)

^b Bundang CHA Hospital   (South Korea)

^c Yonsei University College of Medicine   (South Korea)

^d Hanyang University   (South Korea)

^e National Cancer Center   (South Korea)

Author keywords

Behavioral recovery; Human embryonic stem cell derived neural precursor cells (hESC NPCs, ENStem A); Magnetic resonance imaging (MRI); Migration; Stroke

Indexed keywords

BIOLOGICAL MARKER; CHEMOKINE RECEPTOR CXCR4; FERRIC FERROCYANIDE; GLIAL FIBRILLARY ACIDIC PROTEIN; NESTIN; NEURON SPECIFIC NUCLEAR PROTEIN; PHOSPHOPROTEIN DARPP 32; PROTEIN TUJ1; UNCLASSIFIED DRUG; CXCR4 PROTEIN, RAT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN REGION; CELL DEATH; CELL FATE; CELL MIGRATION; CEREBROVASCULAR ACCIDENT; EMBRYO; EMBRYONIC STEM CELL; EXPERIMENTAL BEHAVIORAL TEST; GLIOSIS; HUMAN; HUMAN CELL; HUMAN EMBRYONIC STEM CELL DERIVED NEURAL PRECURSOR CELL; IMMUNOHISTOCHEMISTRY; MALE; NERVE CELL DIFFERENTIATION; NERVOUS TISSUE; NEURAL STEM CELL TRANSPLANTATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; RAT; ROTAROD TEST; SCAR FORMATION; SENSORIMOTOR FUNCTION; SIGNAL DETECTION; STAINING; STEPPING AND MODIFIED NEUROLOGICAL SEVERITY SCORE TEST; TISSUE REPAIR; TREATMENT OUTCOME; ANIMAL; CELL DIFFERENTIATION; CELL MOTION; CYTOLOGY; GENETICS; INFARCTION, MIDDLE CEREBRAL ARTERY; METABOLISM; NEURAL STEM CELL; PATHOLOGY; PATHOPHYSIOLOGY; PSYCHOMOTOR PERFORMANCE; SPRAGUE DAWLEY RAT; TRANSPLANTATION; CEREBRAL ARTERY DISEASE;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL MOVEMENT; EMBRYONIC STEM CELLS; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; NEURAL STEM CELLS; PSYCHOMOTOR PERFORMANCE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CXCR4;

EID: 84892181368     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2013.93     Document Type: Article

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