Membrane lipids are key modulators of the endocannabinoid-hydrolase FAAH

Biochemical Journal

Volumn 457, Issue 3, 2014, Pages 463-472

  Dainese, Enrico ^a,b   De Fabritiis, Gianni ^c   Sabatucci, Annalaura ^a   Oddi, Sergio ^a   Angelucci, Clotilde Beatrice ^a   Di Pancrazio, Chiara ^a   Giorgino, Toni ^d   Stanley, Nathaniel ^c   Del Carlo, Michele ^a   Cravatt, Benjamin F ^e   Maccarrone, Mauro ^b,f  

^a UNIVERSITY OF TERAMO   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c UNIVERSITAT POMPEU FABRA   (Spain)

^d CNR   (Italy)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

^f UNIVERSITY CAMPUS BIO MEDICO   (Italy)

Author keywords

Cholesterol; Endocannabinoid; Fatty acid amide hydrolase (FAAH); Lipid; Membrane

Indexed keywords

ANANDAMIDE; CHOLESTEROL; DIMER; FATTY ACID AMIDASE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME STRUCTURE; LIPID BILAYER; LIPID MEMBRANE; MEMBRANE BINDING; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; SIMULATION;

AMIDOHYDROLASES; ANIMALS; CELL LINE; CELL MEMBRANE; CHOLESTEROL; DETERGENTS; DIMERIZATION; ENDOCANNABINOIDS; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME INHIBITORS; HYDROLYSIS; LIVER; MICE; MODELS, BIOLOGICAL; NEURONS; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN STABILITY; PROTEIN TRANSPORT; RATS; RECOMBINANT PROTEINS;

EID: 84892174478     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20130960     Document Type: Article

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