A fully synthetic and biochemically validated phosphatidyl inositol-3-phosphate hapten via asymmetric synthesis and native chemical ligation

Journal of the American Chemical Society

Volumn 136, Issue 1, 2014, Pages 412-418

  Chandler, Brent D ^a   Burkhardt, Anne L ^b   Foley, Klaudia ^b   Cullis, Courtney ^b   Driscoll, Denise ^b   Roy D'Amore, Natalie ^b   Miller, Scott J ^a  

^a YALE UNIVERSITY   (United States)

^b TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ASYMMETRIC SYNTHESIS; CYSTEINE RESIDUES; IMMUNOGENS; KEYHOLE LIMPET HEMOCYANINS; NATIVE CHEMICAL LIGATION; PHOSPHOINOSITIDES; SULFHYDRYL;

ALCOHOLS; AMINO ACIDS; CATALYSIS; SUGARS;

POLYOLS;

CYSTEINE; DICYCLOHEXYLCARBODIIMIDE; GLUTATHIONE TRANSFERASE; HAPTEN; IMMUNOGLOBULIN G; INOSITOL; KEYHOLE LIMPET HEMOCYANIN; MALEIMIDE; NUCLEOPHILE; OVALBUMIN; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PHOSPHORAMIDOUS ACID; STEARIC ACID; THIOL DERIVATIVE;

ARTICLE; ASYMMETRIC CATALYSIS; ASYMMETRIC SYNTHESIS; CONJUGATION; COVALENT BOND; ENANTIOMER; HYDROGENOLYSIS; IMMUNE RESPONSE; NATIVE CHEMICAL LIGATION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN PHOSPHORYLATION; STEREOCHEMISTRY; STEREOISOMERISM; WESTERN BLOTTING;

CYSTEINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HAPTENS; INOSITOL PHOSPHATES; PHOSPHATIDYLINOSITOLS;

EID: 84892171259     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja410750a     Document Type: Article

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