Effects of mosapride on secondary peristalsis in patients with ineffective esophageal motility

Scandinavian Journal of Gastroenterology

Volumn 48, Issue 12, 2013, Pages 1363-1370

  Chen, Chien Lin ^a   Yi, Chih Hsun ^a   Liu, Tso Tsai ^a   Orr, William C ^b  

^a TZU CHI UNIVERSITY   (Taiwan)

^b UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

Author keywords

Ineffective esophageal motility; Mosapride; Secondary peristalsis

Indexed keywords

MOSAPRIDE; PLACEBO;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ESOPHAGUS FUNCTION DISORDER; ESOPHAGUS MANOMETRY; ESOPHAGUS MOTILITY; FEMALE; HUMAN; MALE; MIDDLE AGED; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SECONDARY PERISTALSIS; TREATMENT OUTCOME;

ADULT; AGED; BENZAMIDES; ESOPHAGEAL MOTILITY DISORDERS; ESOPHAGUS; FEMALE; GASTROESOPHAGEAL REFLUX; GASTROINTESTINAL AGENTS; HUMANS; MALE; MANOMETRY; MIDDLE AGED; MORPHOLINES; PERISTALSIS; PRESSURE; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 84892154520     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2013.840856     Document Type: Article

References (35)

1. Dodds WJ, Dent J, Hogan WJ, Helm JF, Hauser R, Patel GK, et al. Mechanisms of gastroesophageal reflux in patients with reflux esophagitis. N Engl J Med 1982;307: 1547-52
2. Kahrilas PJ, Dodds WJ, Hogan WJ, Kern M, Arndorfer RC, Reece A. Esophageal peristaltic dysfunction in peptic esophagitis. Gastroenterology 1986;91:897-904
3. Olsen AM, Schlegel JF. Motility disturbances caused by esophagitis. J Thorac Cardiovasc Surg 1965;50:607-12
4. Leite LP, Johnston BT, Barrett J, Castell JA, Castell DO. Ineffective esophageal motility (IEM): The primary finding in patients with nonspecific esophageal motility disorder. Dig Dis Sci 1997;42:1859-65
5. Helm JF, Dodds WJ, Pelc LR, Palmer DW, Hogan WJ, Teeter BC. Effect of esophageal emptying and saliva on clearance of acid from the esophagus. N Engl J Med 1984; 310:284-8
6. Schoeman MN, Holloway RH. Stimulation and characteristics of secondary oesophageal peristalsis in normal subjects. Gut 1994;35:152-8
7. Hwang K. Mechanism of transportation of the content of the esophagus. J Appl Physiol 1954;6:781-96
8. Paterson WG. Neuromuscular mechanisms of esophageal responses at and proximal to a distending balloon. Am J Physiol 1991;260:G148-55
9. Kravitz JJ, Snape WJ Jr, Cohen S. Effect of thoracic vagotomy and vagal stimulation on esophageal function. Am J Physiol 1978;234:E359-64
10. Lang IM, Medda BK, Shaker R. Mechanisms of reflexes induced by esophageal distension. Am J Physiol Gastrointest Liver Physiol 2001;281:G1246-63
11. Ruth M, Finizia C, Cange L, Lundell L. The effect of mosapride on oesophageal motor function and acid reflux in patients with gastro-oesophageal reflux disease. Eur J Gastroenterol Hepatol 2003;15:1115-21
12. Ruth M, Hamelin B, Rohss K, Lundell L. The effect of mosapride, a novel prokinetic, on acid reflux variables in patients with gastro-oesophageal reflux disease. Aliment Pharmacol Ther 1998;12:35-40
13. Cho YK, Choi MG, Han HW, Park JM, Oh JH, Jeong JJ, et al. The effect of mosapride on esophageal motility and bolus transit in asymptomatic volunteers. J Clin Gastroenterol 2006;40:286-92
14. Koshino K, Adachi K, Furuta K, Ohara S, Morita T, Nakata S, et al. Effects of mosapride on esophageal functions and gastroesophageal reflux. J Gastroenterol Hepatol 2010; 25:1066-71
15. Chen CL, Liu TT, Yi CH, Orr WC. Effects of mosapride on esophageal secondary peristalsis in humans. Neurogastroenterol Motil 2011;23:606-e249
16. Chen CL, Yi CH. Assessment of esophageal motor function using combined multichannel intraluminal impedance and manometry in healthy volunteers: A single-center study in Taiwan. J Gastroenterol Hepatol 2007;22:1039-43
17. Tutuian R, Castell DO. Clarification of the esophageal function defect in patients with manometric ineffective esophageal motility: Studies using combined impedancemanometry. Clin Gastroenterol Hepatol 2004;2:230-6
18. Itoh H, Nagano T, Takeyama M. Effects of mosapride citrate on human plasma levels of motilin, gastrin, somatostatin, and secretin. Biol Pharm Bull 2001;24:1072-5
19. Chen CL, Szczesniak MM, Cook IJ. Oesophageal bolus transit and clearance by secondary peristalsis in normal individuals. Eur J Gastroenterol Hepatol 2008;20:1129-35
20. Makimoto N, Sakurai-Yamashita Y, FuruichiA, Kawakami S, EnjojiA,KanematsuT,et al. In vivo assessmentof acceleration of motor activity associated with acetylcholine release via 5-hydroxytryptamine4 receptor in dog intestine. Jpn J Pharmacol 2002;90:28-35
21. Christensen J. Origin of sensation in the esophagus. Am J Physiol 1984;246:G221-5
22. Mei N. Gastrointestinal vagal mechanoreceptors in the cat. Exp Brain Res 1970;11:502-14
23. Moummi C, Yang DC, Gullikson GW. 5-HT4 receptor activation induces relaxation and associated cAMP generation in rat esophagus. Eur J Pharmacol 1992; 216:47-52
24. Grider Jr. Neurotransmitters mediating the intestinal peristaltic reflex in the mouse. J Pharmacol Exp Ther 2003;307: 460-7
25. Castell DO. Medical therapy for reflux esophagitis: 1986 and beyond. Ann Intern Med 1986;104:112-14
26. Corazziari E, Bontempo I, Anzini F. Effects of cisapride on distal esophageal motility in humans. Dig Dis Sci 1989;34: 1600-5
27. Grande L, Lacima G, Ros E, Garcia-Valdecasas JC, Fuster J, Visa J, et al. Lack of effect of metoclopramide and domperidone on esophageal peristalsis and esophageal acid clearance in reflux esophagitis. A randomized, double-blind study. Dig Dis Sci 1992;37:583-8
28. Koutsoumbi P,EpanomeritakisE,Tsiaoussis J,AthanasakisH, Chrysos E, Zoras O, et al.The effect of erythromycin onhuman esophageal motility is mediated by serotonin receptors. Am J Gastroenterol 2000;95:3388-92
29. Holloway RH. Topographical clinical esophageal manometry: A better mousetrap or manometric overkill? Am J Gastroenterol 2000;95:2677-9
30. Park H, Conklin JL. Neuromuscular control of esophageal peristalsis. Curr Gastroenterol Rep 1999;1:186-97
31. Schoeman MN, Holloway RH. Integrity and characteristics of secondary oesophageal peristalsis in patients with gastrooesophageal reflux disease. Gut 1995;36:499-504
32. Orr WC, Robinson MG, Johnson LF. Acid clearance during sleep in the pathogenesis of reflux esophagitis. Dig Dis Sci 1981;26:423-7
33. Schoeman MN, Tippett MD, Akkermans LM, Dent J, Holloway RH. Mechanisms of gastroesophageal reflux in ambulant healthy human subjects. Gastroenterology 1995; 108:83-91
34. Basilisco G, Carola F, Vanoli M, Bianchi P, Barbera R. Oesophageal acid clearance in patients with systemic sclerosis: Effect of body position. Eur J Gastroenterol Hepatol 1996;8:205-9
35. Fornari F, Blondeau K, Durand L, Rey E, Diaz-Rubio M, De Meyer A, et al. Relevance of mild ineffective oesophageal motility (IOM) and potential pharmacological reversibility of severe IOM in patients with gastrooesophageal reflux disease. Aliment Pharmacol Ther 2007;26:1345-54