The effect of erythromycin on human esophageal motility is mediated by serotonin receptors

American Journal of Gastroenterology

Volumn 95, Issue 12, 2000, Pages 3388-3392

  Koutsoumbi, Paraskevi ^a   Epanomeritakis, Emmanuel ^a   Tsiaoussis, John ^a   Athanasakis, Helias ^a   Chrysos, Emmanuel ^a   Zoras, Odysseas ^a   Vassilakis, John Sophocles ^a   Xynos, Evaghelos ^a  

^a UNIVERSITY HOSPITAL OF HERAKLION   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; ERYTHROMYCIN; ERYTHROMYCIN ETHYLSUCCINATE; ONDANSETRON; PLACEBO; PROKINETIC AGENT; SEROTONIN 3 RECEPTOR;

ADULT; ARTICLE; CHOLINERGIC SYSTEM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG ANTAGONISM; DRUG EFFECT; DRUG MECHANISM; ESOPHAGUS MANOMETRY; ESOPHAGUS MOTILITY; FEMALE; HUMAN; HUMAN EXPERIMENT; LOWER ESOPHAGUS SPHINCTER PRESSURE; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; ATROPINE; DOUBLE-BLIND METHOD; ERYTHROMYCIN; ESOPHAGUS; FEMALE; GASTROINTESTINAL AGENTS; HUMANS; MALE; MANOMETRY; ONDANSETRON; PERISTALSIS; RECEPTORS, SEROTONIN;

EID: 0033638406     PISSN: 00029270     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9270(00)02071-2     Document Type: Article

References (28)

1. Erythromycin, motilin, and the esophagus
2. Motilin agonist erythromycin increases human lower esophageal sphincter pressure by stimulation of cholinergic nerves
3. The effect of intravenous erythromycin on esophageal motility in healthy subjects
4. Effect of erythromycin on gastroesophageal reflux in reflux esophagitis
5. Erythromycin accelerates gastric emptying by inducing antral contractions and improved gastroduodenal coordination
6. The effect of erythromycin in gastric emptying of solids and hypertonic liquids in healthy subjects
7. Erythromycin improves delayed gastric emptying in diabetic gastroparesis
8. Effects of oral erythromycin on fasting and postprandial antroduodenal motility in patients with type I diabetes, measured with an ambulatory manometric technique
9. Effects of octreotide and erythromycin on gastric myoelectrical and motor activities in patients with gastroparesis
10. Effect of octreotide and erythromycin on idiopathic and scleroderma-associated intestinal pseudoobstruction
11. Erythromycin accelerates delayed gastric emptying of solids in patients after truncal vagotomy and pyloroplasty
12. Macrolide antibiotics are motilin receptors agonists
13. Erythromycin acts on presynaptic neurons to stimulate gastrointestinal motor activity
14. Mechanism of gastroprokinetic effect of EM523, an erythromycin derivative, in dogs
15. Erythromycin accelerates gastric and gallbladder emptying through a cholinergic mechanism
16. The gastrokinetic effects of erythromycin: Myogenic and neurogenic mechanisms of action in the rabbit stomach
17. Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve
18. Selection and functional 5-hydroxytryptamine 3 receptor antagonism by BRL 43694 (granisetron)
19. Involvement of 5-hydroxytryptamine 3 receptors in regulation of interdigestive gastric contractions by motilin in the dog
20. Vagus-dependent and vagus-independent mechanisms of action of erythromycin derivative EM574 and motilin in dogs
21. Erythromycin is a motilin receptor agonist
22. Effect of motilin on the lower esophageal sphincter
23. Motilin: A mechanism incorporating the opossum lower esophageal sphincter into the migrating motor complex
24. Interdigestive phasic contractions of the human lower esophageal sphincter
25. Vagal control of migrating motor complex in the dog
26. Effect of nonpeptide motilin agonist EM523 on release of gut and pancreatic hormones in conscious dogs
27. Effect of central administration of motilin on migrating motor complexes in the dog
28. Erythromycin inhibits rabbit pyloric smooth muscle through neuronal motilin receptors