Cytotoxicity of Vitex agnus-castus fruit extract and its major component, casticin, correlates with differentiation status in leukemia cell lines

International Journal of Oncology

Volumn 43, Issue 6, 2013, Pages 1976-1984

  Kikuchi, Hidetomo ^a,b   Yuan, Bo ^a   Nishimura, Yoshio ^b   Imai, Masahiko ^a   Furutani, Ryota ^a   Kamoi, Saki ^a   Seno, Misako ^a   Fukushima, Shin ^a   Hazama, Shingo ^a   Hirobe, Chieko ^c   Ohyama, Kunio ^a   Hu, Xiao Mei ^a   Takagi, Norio ^a   Hirano, Toshihiko ^a   Toyoda, Hiroo ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b YASUDA WOMEN'S UNIVERSITY   (Japan)

^c Seisen University   (Japan)

Author keywords

Apoptosis induction; Casticin; Differentiation; Intercellular adhesion molecule 1; Leukemic cells; Vitex agnus castus

Indexed keywords

BETA ACTIN; CALCITRIOL; CASTICIN; CD11B ANTIGEN; DNA; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; MONOCLONAL ANTIBODY; PHORBOL 13 ACETATE 12 MYRISTATE; UNCLASSIFIED DRUG; VITEX AGNUS CASTUS EXTRACT;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL STRAIN HL 60; CELL STRAIN U937; CELL VIABILITY ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA SEQUENCE; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL; VITEX AGNUS CASTUS;

ADULT; APOPTOSIS; CALCITRIOL; CALCIUM CHANNEL AGONISTS; CARCINOGENS; CELL ADHESION; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DRUG RESISTANCE, NEOPLASM; DRUGS, CHINESE HERBAL; FLAVONOIDS; HL-60 CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LEUKEMIA; PLANT EXTRACTS; TETRADECANOYLPHORBOL ACETATE;

EID: 84891957619     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.2133     Document Type: Article

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