Downregulation of DENND2D by promoter hypermethylation is associated with early recurrence of hepatocellular carcinoma

International Journal of Oncology

Volumn 44, Issue 1, 2014, Pages 44-52

  Kanda, Mitsuro ^a   Nomoto, Shuji ^a   Oya, Hisaharu ^a   Takami, Hideki ^a   Hibino, Soki ^a   Hishida, Mitsuhiro ^a   Suenaga, Masaya ^a   Yamada, Suguru ^a   Inokawa, Yoshikuni ^a   Nishikawa, Yoko ^a   Asai, Mikako ^a   Fujii, Tsutomu ^a   Sugimoto, Hiroyuki ^a   Kodera, Yasuhiro ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

DENND2D; DNA methylation; Expression; Hepatocellular carcinoma; Tumor suppressor

Indexed keywords

BIOLOGICAL MARKER; DENND2D PROTEIN; MESSENGER RNA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER TISSUE; CONTROLLED STUDY; CPG ISLAND; DENND2D GENE; DISEASE ASSOCIATION; DNA METHYLATION; DOWN REGULATION; EARLY CANCER; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, HEPATOCELLULAR; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; PROMOTER REGIONS, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 84891938138     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.2165     Document Type: Article

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