Tumor-associated fibroblasts isolated from colorectal cancer tissues exhibit increased ICAM-1 expression and affinity for monocytes

Oncology Reports

Volumn 31, Issue 1, 2014, Pages 255-261

  Schellerer, Vera S ^a   Langheinrich, Melanie ^a   Hohenberger, Werner ^a   Croner, Roland S ^a   Merkel, Susanne ^a   Rau, Tilman T ^a   Stürzl, Michael ^a   Naschberger, Elisabeth ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

Colorectal cancer; Intercellular adhesion molecule 1; Normal tissue associated fibroblasts; Tumor microenvironment; Tumor associated fibroblasts

Indexed keywords

CD20 ANTIGEN; CD45 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; VIMENTIN;

ADULT; AGED; ARTICLE; BINDING AFFINITY; CELL ADHESION; CELL INTERACTION; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR ASSOCIATED FIBROBLAST;

AGED; AGED, 80 AND OVER; ANTIGENS, CD45; CELL ADHESION; CELL LINE, TUMOR; CELL SEPARATION; COLORECTAL NEOPLASMS; DISEASE PROGRESSION; FEMALE; FIBROBLASTS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; KERATIN-20; MALE; MIDDLE AGED; MONOCYTES; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS; VIMENTIN;

EID: 84891922765     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2860     Document Type: Article

References (36)

1. Saunders M and Iveson T: Management of advanced colorectal cancer: state of the art. Br J Cancer 95: 131-138, 2006.
2. Parkin DM, Bray F, Ferlay J and Pisani P: Global cancer statistics, 2002. CA Cancer J Clin 55: 74-108, 2005.
3. Din FV, Theodoratou E, Farrington SM, Tenesa A, Barnetson RA, Cetnarskyj R, et al: Effect of aspirin and NSAIDs on risk and survival from colorectal cancer. Gut 59: 1670-1679, 2010.
4. Wang D and Dubois RN: The role of COX-2 in intestinal inflammation and colorectal cancer. Oncogene 29: 781-788, 2010.
5. Lakatos PL and Lakatos L: Risk for colorectal cancer in ulcerative colitis: changes, causes and management strategies. World J Gastroenterol 14: 3937-3947, 2008.
6. Strell C, Rundqvist H and Ostman A: Fibroblasts - a key host cell type in tumor initiation, progression, and metastasis. Ups J Med Sci 117: 187-195, 2012.
7. Benson V, McMahon AC and Lowe HC: ICAM-1 in acute myocardial infarction: a potential therapeutic target. Curr Mol Med 7: 219-227, 2007.
8. Niessen HW, Lagrand WK, Visser CA, Meijer CJ and Hack CE: Upregulation of ICAM-1 on cardiomyocytes in jeopardized human myocardium during infarction. Cardiovasc Res 41: 603-610, 1999.
9. Huang WC, Chan ST, Yang TL, Tzeng CC and Chen CC: Inhibition of ICAM-1 gene expression, monocyte adhesion and cancer cell invasion by targeting IKK complex: molecular and functional study of novel α-methylene-γ- butyrolactone derivatives. Carcinogenesis 25: 1925-1934, 2004.
10. van de Stolpe A and van der Saag PT: Intercellular adhesion molecule-1. J Mol Med 74: 13-33, 1996.
11. Ksiazek K, Mikula-Pietrasik J, Catar R, Dworacki G, Winckiewicz M, Frydrychowicz M, et al: Oxidative stress-dependent increase in ICAM-1 expression promotes adhesion of colorectal and pancreatic cancers to the senescent peritoneal mesothelium. Int J Cancer 127: 293-303, 2010.
12. Arteta B, Lasuen N, Lopategi A, Sveinbjörnsson B, Smedsrød B, and Vidal-Vanaclocha F: Colon carcinoma cell interaction with liver sinusoidal endothelium inhibits organ-specific antitumor immunity through interleukin-1-induced mannose receptor in mice. Hepatology 51: 2172-2182, 2010.
13. Alexiou D, Karayiannakis AJ, Syrigos KN, Zbar A, Kremmyda A, Bramis I and Tsigris C: Serum levels of E-selectin, ICAM-1 and VCAM-1 in colorectal cancer patients: correlations with clinicopathological features, patient survival and tumour surgery. Eur J Cancer 37: 2392-2397, 2001.
14. Maeda K, Kang SM, Sawada T, Nishiguchi Y, Yashiro M, Ogawa Y, et al: Expression of intercellular adhesion molecule-1 and prognosis in colorectal cancer. Oncol Rep 9: 511-514, 2002.
15. Mantur M, Snarska J, Koper O, Dzieciol J, Plonski A and Lemancewicz D: Serum sICAM, sVCAM and sE-selectin levels in colorectal cancer patients. Folia Histochem Cytobiol 47: 621-625, 2009.
16. Taglia L, Matusiak D, Matkowskyj KA and Benya RV: Gastrin-releasing peptide mediates its morphogenic properties in human colon cancer by upregulating intracellular adhesion protein-1 (ICAM-1) via focal adhesion kinase. Am J Physiol Gastrointest Liver Physiol 292: G182-G190, 2007.
17. Wimmenauer S, Keller H, Rückauer KD, Rahner S, Wolff-Vorbeck G, Kirste G, et al: Expression of CD44, ICAM-1 and N-CAM in colorectal cancer. Correlation with the tumor stage and the phenotypical characteristics of tumor-infiltrating lymphocytes. Anticancer Res 17: 2395-2400, 1997.
18. Kitagawa T, Matsumoto K and Iriyama K: Serum cell adhesion molecules in patients with colorectal cancer. Surg Today 28: 262-267, 1998.
19. Sanchez-Rovira P, Jimenez E, Carracedo J, Barneto IC, Ramirez R and Aranda E: Serum levels of intercellular adhesion molecule 1 (ICAM-1) in patients with colorectal cancer: inhibitory effect on cytotoxicity. Eur J Cancer 34: 394-398, 1998.
20. Kang X, Wang F, Xie JD, Cao J and Xian PZ: Clinical evaluation of serum concentrations of intercellular adhesion molecule-1 in patients with colorectal cancer. World J Gastroenterol 11: 4250-4253, 2005.
21. Alexiou D, Karayiannakis AJ, Syrigos KN, Zbar A, Sekara E, Michail P, et al: Clinical significance of serum levels of E-selectin, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 in gastric cancer patients. Am J Gastroenterol 98: 478-485, 2003.
22. Nakata B, Hori T, Sunami T, Ogawa Y, Yashiro M, Maeda K, et al: Clinical significance of serum soluble intercellular adhesion molecule 1 in gastric cancer. Clin Cancer Res 6: 1175-1179, 2000.
23. Zhang GJ and Adachi I: Serum levels of soluble intercellular adhesion molecule-1 and E-selectin in metastatic breast carcinoma: Correlations with clinicopathological features and prognosis. Int J Oncol 14: 71-77, 1999.
24. O'Hanlon DM, Fitzsimons H, Lynch J, Tormey S, Malone C and Given HF: Soluble adhesion molecules (E-selectin, ICAM-1 and VCAM-1) in breast carcinoma. Eur J Cancer 38: 2252-2257, 2002.
25. Silva HC, Garcao F, Coutinho EC, De Oliveira CF and Regateiro FJ: Soluble VCAM-1 and E-selectin in breast cancer: relationship with staging and with the detection of circulating cancer cells. Neoplasma 53: 538-543, 2006.
26. Perabo F, Sharma S, Gierer R, Wirger A, Fimmers R, Steiner G, et al: Circulating intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and E-selectin in urological malignancies. Indian J Cancer 38: 1-7, 2001.
27. Harning R, Mainolfi E, Bystryn JC, Henn M, Merluzzi VJ and Rothlein R: Serum levels of circulating intercellular adhesion molecule 1 in human malignant melanoma. Cancer Res 51: 5003-5005, 1991.
28. Grothey A, Heistermann P, Philippou S and Voigtmann R: Serum levels of soluble intercellular adhesion molecule-1 (ICAM-1, CD54) in patients with non-small-cell lung cancer: correlation with histological expression of ICAM-1 and tumour stage. Br J Cancer 77: 801-807, 1998.
29. Shimizu Y, Minemura M, Tsukishiro T, Kashii Y, Miyamoto M, Nishimori H, et al: Serum concentration of intercellular adhesion molecule-1 in patients with hepatocellular carcinoma is a marker of the disease progression and prognosis. Hepatology 22: 525-531, 1995.
30. Christiansen I, Sundström C and Tötterman TH: Elevated serum levels of soluble vascular cell adhesion molecule-1 (sVCAM-1) closely reflect tumour burden in chronic B-lymphocytic leukaemia. Br J Haematol 103: 1129-1137, 1998.
31. Jackson AM, Alexandrov AB, Gribben SC, Esuvarnathan K and James K: Expression and shedding of ICAM-1 in bladder cancer and its immunotherapy. Int J Cancer 55: 921-925, 1993.
32. Budnik A, Grewe M, Gyufko K and Krutmann J: Analysis of the production of soluble ICAM-1 molecules by human cells. Exp Hematol 24: 352-359, 1996.
33. Franzke A, Probst-Kepper M, Buer J, Duensing S, Hoffmann R, Wittke F, et al: Elevated pretreatment serum levels of soluble vascular cell adhesion molecule 1 and lactate dehydrogenase as predictors of survival in cutaneous metastatic malignant melanoma. Br J Cancer 78: 40-45, 1998.
34. Schellerer VS, Croner RS, Weinländer K, Hohenberger W, Stürzl M and Naschberger E: Endothelial cells of human colorectal cancer and healthy colon reveal phenotypic differences in culture. Lab Invest 87: 1159-1170, 2007.
35. Desmoulière A, Guyot C and Gabbiani G: The stroma reaction myofibroblast: a key player in the control of tumor cell behavior. Int J Dev Biol 48: 509-517, 2004.
36. Gonda TA, Varro A, Wang TC and Tycko B: Molecular biology of cancer-associated fibroblasts: can these cells be targeted in anti-cancer therapy? Semin Cell Dev Biol 21: 2-10, 2010.