How to fight back against antibiotic resistance

American Scientist

Volumn 102, Issue 1, 2014, Pages 42-51

  Dantas, Gautam ^a   Sommer, Morten O A ^b  

^a WASHINGTON UNIVERSITY   (United States)

^b Technical University of Denmark   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ORGANELLE; DISEASE PREVALENCE; DRUG RESISTANCE; GENE EXPRESSION; GENOME; HABITAT TYPE; HOST-PATHOGEN INTERACTION; MAPPING METHOD; RESEARCH WORK;

EID: 84891913018     PISSN: 00030996     EISSN: None     Source Type: Trade Journal    
DOI: 10.1511/2014.106.42     Document Type: Article

References (10)

1. Aarestrup, F. M. 1999. Association between the consumption of antimicrobial agents in animal husbandry and the occurrence of resistant bacteria among food animals. International Journal of Antimicrobial Agents 12: 279-285.
2. Cabello, F. C. 2006. Heavy use of prophylactic antibiotics in aquaculture: A growing problem for human and animal health and for the environment. Environmental Microbiology 8: 1137-1144.
3. Dantas, G., and M. O. A. Sommer. 2012. Context matters - the complex interplay between resistome genotypes and resistance phenotypes. Current Opinion in Microbiology 15: 577-582.
4. Dantas, G., M. O. A. Sommer, P. H. Degnan, and A. L. Goodman. 2013. Experimental approaches for defining functional roles of microbes in the human gut. Annual Reviews of Microbiology 67: 459-475.
5. Dantas, G., M. O. A. Sommer, R. D. Oluwasegun, and G. M. Church. 2008. Bacteria subsisting on antibiotics. Science 320: 100-103.
6. Forsberg, K. J., A. Reyes, B. Wang, E. M. Selleck, M. O. A. Sommer, and G. Dantas. 2012. The shared antibiotic resistome of soil bacteria and human pathogens. Science 337: 1107-1111.
7. Imamovic, L., and M. O. A. Sommer. 2013. Use of collateral sensitivity networks to design drug cycling protocols that avoid resistance development. Science Translational Medicine 5: 204ra132.
8. Moore, A.M., et al. 2013. Pediatric fecal microbiota harbor diverse and novel antibiotic resistance genes. PLoS One 8(11): e78822.
9. Sommer, M. O. A., and G. Dantas. 2011. Antibiotics and the resistant microbiome. Current Opinion in Microbiology 14: 556-563.
10. Sommer, M. O. A., G. Dantas, and G. M. Church. 2009. Functional characterization of the antibiotic resistance reservoir in the human microflora. Science 325: 1128-1131.