|
Volumn 24, Issue 2, 2014, Pages 571-575
|
Synthesis of tricyclic fused coumarin sulfonates and their inhibitory effects on LPS-induced nitric oxide and PGE2 productions in RAW 264.7 macrophages
|
Author keywords
Antiinflammatory; Coumarin; Nitric oxide; PGE2; Sulfonate; Tricyclic fused coumarin
|
Indexed keywords
ANTIINFLAMMATORY AGENT;
COUMARIN DERIVATIVE;
CYCLOOXYGENASE 2;
INDUCIBLE NITRIC OXIDE SYNTHASE;
IROSUSTAT;
LIPOPOLYSACCHARIDE;
N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE;
NITRIC OXIDE;
PROSTAGLANDIN E2;
SULFONIC ACID DERIVATIVE;
N6 (1 IMINOETHYL)LYSINE;
TRICYCLIC COUMARIN SULFONIC ACID DERIVATIVE;
UNCLASSIFIED DRUG;
ANTIINFLAMMATORY ACTIVITY;
ARTICLE;
CONTROLLED STUDY;
DRUG ABSORPTION;
DRUG BIOAVAILABILITY;
DRUG CYTOTOXICITY;
DRUG DISTRIBUTION;
DRUG EFFECT;
DRUG EXCRETION;
DRUG METABOLISM;
DRUG SYNTHESIS;
ENZYME ACTIVITY;
ENZYME INHIBITION;
MACROPHAGE;
PROTEIN EXPRESSION;
RAW 264.7 MACROPHAGE;
STRUCTURE ACTIVITY RELATION;
CYTOTOXICITY;
DRUG POTENCY;
IC50;
RHODOCOCCUS RHODOCHROUS;
ANTIINFLAMMATORY;
COUMARIN;
NITRIC OXIDE;
PGE(2);
SULFONATE;
TRICYCLIC FUSED COUMARIN;
ANIMALS;
CELL LINE;
COUMARINS;
DINOPROSTONE;
DOSE-RESPONSE RELATIONSHIP, DRUG;
LIPOPOLYSACCHARIDES;
MACROPHAGES;
MICE;
NITRIC OXIDE;
SULFONIC ACIDS;
|
EID: 84891890612
PISSN: 0960894X
EISSN: 14643405
Source Type: Journal
DOI: 10.1016/j.bmcl.2013.12.018 Document Type: Article |
Times cited : (24)
|
References (16)
|