Anti-inflammatory effect of IMMLG5521, a coumarin derivative, on Sephadex-induced lung inflammation in rats

International Immunopharmacology

Volumn 14, Issue 2, 2012, Pages 145-149

  Li, Zhipeng ^a   Hu, Jinfeng ^a   Sun, Mingna ^a   Ji, Haijie ^a   Chu, Shifeng ^a   Liu, Gang ^a   Chen, Naihong ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Coumarin derivative; Eosinophilia; ICAM 1; Inflammation; Lungs; VCAM 1

Indexed keywords

ANTIINFLAMMATORY AGENT; COUMARIN DERIVATIVE; IMMLG 5521; INTERCELLULAR ADHESION MOLECULE 1; SEPHADEX; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DOWN REGULATION; GRANULOMA; LUNG LAVAGE; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL MOVEMENT; COUMARINS; DEXTRANS; EOSINOPHILS; GRANULOMA; INTERCELLULAR ADHESION MOLECULE-1; LUNG; MALE; NEUTROPHILS; PNEUMONIA; RATS; RATS, SPRAGUE-DAWLEY; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84864044803     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.06.004     Document Type: Article

References (26)

1. J.R.S. Hoult, and M. Payá Pharmacological and biochemical actions of simple coumarins: natural products with therapeutic potential Gen Pharmacol 27 4 1996 713 722 (Pubitemid 26233347)
2. K.C. Fylaktakidou, D.R. Gautam, D.J. Hadjipavlou-Litina, C.A. Kontogiorgis, K.E. Litinas, and D.N. Nicolaides Reactions of 4-methylchromene-2,7,8-trione with phosphonium ylides. Synthesis and evaluation of fused 1, 3-dioxolaneocoumarins as antioxidants and antiinflammatories J Chem Soc Perkin Trans 1 2001 3073 3079
3. C. Kontogiorgis, and D. Hadjipavlou-Litina Biological evaluation of several coumarin derivatives designed as possible antiinflammatory/antioxidant agents J Enzyme Inhib Med Chem 18 1 2003 63 69 (Pubitemid 36221716)
4. D.N. Nicolaides, D.R. Gautam, K.E. Litinas, D.J. Hadjipavlou-Litina, and C.A. Kontogiorgis Synthesis and biological evaluation of Benzo[7,8]chromeno[5,6- b][1,4]oxazin-3-ones J Heterocycl Chem 41 4 2004 605 611
5. E.Y. Bissonnette, G.M. Tremblay, V. Turmel, B. Pirotte, and M. Reboud-Ravaux Coumarinic derivatives show anti-inflammatory effects on alveolar macrophages, but their anti-elastase activity is essential to reduce lung inflammation in vivo Int Immunopharmacol 9 1 2009 49 54
6. J.F. Vasconcelos, M.M. Teixeira, J.M. Barbosa-Filho, M.F. Agra, X.P. Nunes, and A.M. Giulietti Effects of umbelliferone in a murine model of allergic airway inflammation Eur J Pharmacol 609 1-3 2009 126 131
7. P.J. Barnes Pathophysiology of asthma Br J Clin Pharmacol 42 1 1996 3 10 (Pubitemid 26230047)
8. P.J. Barnes, K.F. Chung, and C.P. Page Inflammatory mediators of asthma Pharmacol Rev 50 4 1998 515 596
9. A.J. Wardlaw, and A.B. Kay The role of the eosinophil in the pathogenesis of asthma Allergy 42 5 1987 321 335 (Pubitemid 17105173)
10. G.J. Gleich, N.A. Flavahan, T. Fujisawa, and P.M. Vanhoutte The eosinophil as a mediator of damage to respiratory epithelium: a model for bronchial hyperreactivity J Allergy Clin Immunol 81 1988 776 781
11. J. Bousquet, P. Chanez, J.Y. Lacoste, G. Barneon, N. Ghavanian, and I. Enander Eosinophilic inflammation in asthma N Engl J Med 323 15 1990 1033 1039 (Pubitemid 20336962)
12. G. Li, D.M. Wang, M.N. Sun, G.Y. Li, J.F. Hu, and Y. Zhang Discovery and optimization of novel 3-piperazinylcoumarin antagonist of chemokine-like factor 1 with oral antiasthma activity in mice J Med Chem 53 4 2010 1741 1754
13. Z.P. Li, J.F. Hun, M.N. Sun, H.J. Ji, M. Zhao, and D.H. Wu Effect of compound IMMLG5521, a novel coumarin derivative, on carrageenan-induced pleurisy in rats Eur J Pharmacol 661 1-3 2011 118 123
14. A.M. Mastrangelo, T.M. Jeitner, and J.W. Eaton Oleic acid increases cell surface expression and activity of CD11b on human neutrophils J Immunol 161 8 1998 4268 4275 (Pubitemid 28469010)
15. D.W. Swank, and S.B. Moore Roles of the neutrophil and other mediators in adult respiratory distress syndrome Mayo Clin Proc 64 9 1989 1118 1132 (Pubitemid 19283034)
16. F. Dallegri, and L. Ottonello Tissue injury in neutrophilic inflammation Inflamm Res 46 10 1997 382 391 (Pubitemid 27478595)
17. EB Haddad, S.L. Underwood, D. Dabrowski, M.A. Birrell, K. McCluskie, and C.H. Battram Critical role for T cells in Sephadex-induced airway inflammation: pharmacological and immunological characterization and molecular biomarker identification J Immunol 168 6 2002 3004 3016 (Pubitemid 34211682)
18. P.M. Harrington, D.J. Newton, C.M. Williams, J.A. Hunt, R.J. Dearman, and I. Kimber Eotaxin and eotaxin receptor (CCR3) expression in Sephadex particle-induced rat lung inflammation Int J Exp Pathol 80 3 1999 177 185 (Pubitemid 29349741)
19. M.T. Namovic, R.E. Walsh, C. Goodfellow, R.R. Harris, G.W. Carter, and R.L. Bell Pharmacological modulation of eosinophil influx into the lungs of Brown Norway rats Eur J Pharmacol 315 1 1996 81 88 (Pubitemid 26390953)
20. J.S. Pober, and W.C. Sessa Evolving functions of endothelial cells in inflammation Nat Rev 7 2007 803 815 (Pubitemid 47480307)
21. K. Ley, C. Laudanna, M.I. Cybulsky, and S. Nourshargh Getting to the site of inflammation: the leukocyte adhesion cascade updated Nat Rev 7 2007 678 689 (Pubitemid 47327397)
22. A.R. Burns, C.W. Smith, and D.C. Walker Unique structural features that influence neutrophil emigration into the lung Physiol Rev 83 2 2003 309 336 (Pubitemid 36378675)
23. T.M. Carlos, and J.M. Harlan Leukocyte-endothelial adhesion molecules Blood 84 7 1994 2068 2101 (Pubitemid 24296363)
24. K. Iiyama, L. Hajra, M. Iiyama, H. Li, M. Di Chiara, and B.D. Medoff Patterns of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit and mouse atherosclerotic lesions and at sites predisposed to lesion formation Circ Res 85 1999 199 207 (Pubitemid 29343319)
25. S.K. Lo, J. Everitt, J. Gu, and A.B. Malik Tumor necrosis factor mediates experimental pulmonary edema by ICAM-1 and CD18-dependent mechanisms J Clin Invest 89 1992 981 988
26. P.J. Barnes, and M. Karin Nuclear factor-κB-a pivotal transcriptional factor in chronic inflammatory diseases N Engl J Med 336 1997 1066 1071 (Pubitemid 27163860)