Driving on antidepressants: Cruising for a crash?

Psychiatry

Volumn 6, Issue 9, 2009, Pages 13-16

  Sansone, Randy A ^a,b   Sansone, Lori A ^c  

^a WRIGHT STATE UNIVERSITY   (United States)

^b KETTERING MEDICAL CENTER   (United States)

^c WRIGHT PATTERSON AIR FORCE BASE   (United States)

Author keywords

Antidepressants; Driving; Motor vehicle; Psychotropic medications

Indexed keywords

ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE; PSYCHOTROPIC AGENT;

DEPRESSION; DISEASE SEVERITY; DRIVING ABILITY; HUMAN; PATIENT COUNSELING; PRESCRIPTION; REVIEW; RISK ASSESSMENT;

EID: 77649201615     PISSN: 15505952     EISSN: 15555194     Source Type: Journal    
DOI: None     Document Type: Review

References (17)

1. Morbidity and Mortality Weekly Report. Centers for Disease Control and Prevention. Notice to readers: United Nations Global Road Safety Week, April 23-29. 2007http://www.cdc.gov/mmwr/ preview/mmwrhtml/mm5615a5.htm. Accessed on 1/8/09.
2. Morbidity and Mortality Weekly Report. Centers for Disease Control and Prevention. Notice to readers: Buckle Up America Week, May 22-29. 2006http://www.cdc.gov/mmwr/ preview/mmwrhtml/mm5519a6.htm. Accessed on 1/8/09.
3. Morbidity and Mortality Weekly Report. Centers for Disease Control and Prevention. QuickStats: age-adjusted death rates for leading causes of injury death, by year, United States, 1979-2004. http://www.cdc.gov/mmwr/ preview/mmwrhtml/mm5550a6.htm. Accessed on 1/8/09.
4. Chen Y, Kelton CM, Jing Y, et al. Utilization, price, and spending trends for antidepressants in the US Medicaid program. Res Social Adm Pharm. 2008;4:244-257.
5. Paulose-Ram R, Safran MA, Jonas BS, Gu Q, Orwig D. Trends in psychotropic medication use among U.S. adults. Pharmacoepidemiol Drug Saf. 2007;16:560-570.
6. Gold Standard, Inc. Fluoxetine. Clinical Pharmacology [database online]. Available at: http://www.clinicalpharmacology. com. Accessed on 1/8/09.
7. Ray WA, Fought RL, Decker MD. Psychoactive drugs and the risk of injurious motor vehicle crashes in elderly drivers. Am J Epidemiol. 1992;136:873-883.
8. Leveille SG, Buchner DM, Koepsell TD, et al. Psychoactive medications and injurious motor vehicle collisions involving older drivers. Epidemiology. 1994;5:591-598.
9. Iwamoto K, Takahashi M, Nakamura Y, et al. The effects of acute treatment with paroxetine, amitriptyline, and placebo on driving performance and cognitive function in healthy Japanese subjects: a double-blind crossover trial. Hum Psychopharmacol. 2008;23:399-407.
10. Bramness JG, Skurtveit S, Neutel CI, Morland J, Engeland A. Minor increase in risk of road traffic accidents after prescriptions of antidepressants: a study of population registry data in Norway. J Clin Psychiatry. 2008;69:1099-1103.
11. Barbone F, McMahon AD, Davey PG, et al. Use of benzodiazepines increased road traffic accidents whereas use of tricyclic antidepressants and SSRIs did not. Lancet. 1998;24:1331-1336.
12. Movig KLL, Mathijssen MPM, Nagel PHA, et al. Psychoactive substance use and the risk of motor vehicle accidents. Accid Anal Prev. 2004;36:631-636.
13. Ramaekers JG. Antidepressants and driver impairment: empirical evidence from a standard on-the-road test. J Clin Psychiatry. 2003;64:20-29.
14. De las Cuevas C, Sanz EJ. Fitness to drive of psychiatric patients. Prim Care Companion. 2008;10:384-390.
15. Dannewitz H, Petros T. Use of antidepressants may impair driving ability. Neuropsychiatry Reviews. 2008; 20-21.
16. Brunnauer A, Laux G, David I, et al. The impact of reboxetine and mirtazapine on driving simulator performance and psychomotor function in depressed patients. J Clin Psychiatry. 2008;69(12):1880-1886.
17. Wheatley D. Psychotropic drugs and road accidents. Br Med J. 1977;2:126-127.