Use of antidepressant agents and the risk of type 2 diabetes

European Journal of Clinical Pharmacology

Volumn 68, Issue 9, 2012, Pages 1295-1302

  Khoza, S ^a   Barner, J C ^b   Bohman, T M ^b   Rascati, K ^b   Lawson, K ^b   Wilson, J P ^b  

^a UNIVERSITY OF ZIMBABWE   (Zimbabwe)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Antidepressant agents; Diabetes mellitus; Retrospective cohort

Indexed keywords

ALPRAZOLAM; ANTIDEPRESSANT AGENT; ANTIDIABETIC AGENT; BENZODIAZEPINE; ESCITALOPRAM; LORAZEPAM; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRICYCLIC ANTIDEPRESSANT AGENT;

ADULT; AGE DISTRIBUTION; ARTICLE; DISEASE ASSOCIATION; ETHNIC DIFFERENCE; FEMALE; FOLLOW UP; HIGH RISK PATIENT; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK ASSESSMENT; SEX DIFFERENCE;

ADOLESCENT; ADRENERGIC UPTAKE INHIBITORS; ADULT; ANTIDEPRESSIVE AGENTS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; INCIDENCE; MALE; MEDICAID; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SEROTONIN UPTAKE INHIBITORS; TEXAS; TIME FACTORS; UNITED STATES; YOUNG ADULT;

EID: 84866619594     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/s00228-011-1168-3     Document Type: Article

References (49)

1. NIHCM Foundation (2001) Prescription drug expenditure in 2001: another year of escalating costs. Accessed July 9 2009
2. Mojtabai R, Olfson M (2008) National patterns in antidepressant treatment by psychiatrists and general medical providers: Results from the national comorbidity survey replication. J Clin Psychiatry 69(7):1064-1074
3. Andersohn F, Schade R, Suissa S, Garbe E (2009) Long-term use of antidepressants for depressive disorders and the risk of diabetes mellitus. Am J Psychiatry 166(5):591-598
4. Brown LC, Majumdar SR, Johnson JA (2008) Type of antidepressant therapy and risk of type 2 diabetes in people with depression. Diabetes Res Clin Pract 79(1):61-67
5. Kivimaki M, Hamer M, Batty GD, Geddes JR, Tabak AG, Pentti J, Virtanen M, Vahtera J (2010) Antidepressant medication use, weight gain, and risk of type 2 diabetes: A population-based study. Diabetes Care 33(12):2611-2616
6. Kivimaki M, Tabak AG, Lawlor DA, Batty GD, Singh-Manoux A, Jokela M, Virtanen M, Salo P, Oksanen T, Pentti J, Witte DR, Vahtera J (2010) Antidepressant use before and after the diagnosis of type 2 diabetes: A longitudinal modeling study. Diabetes Care 33(7):1471-1476
7. Raeder MB, Bjelland I, Vollset SE, Steen VM (2006) Obesity, dyslipidemia, and diabetes with selective serotonin reuptake inhibitors: The hordaland health study. J Clin Psychiatry 67 (12):1974-1982
8. Rubin RR, Ma Y, Marrero DG, Peyrot M, Barrett-Connor EL, Kahn SE, Haffner SM, Price DW, Knowler WC (2008) Elevated depression symptoms, antidepressant medicine use, and risk of developing diabetes during the diabetes prevention program. Diabetes Care 31(3):420-426
9. Rubin RR, Ma Y, Peyrot M, Marrero DG, Price DW, Barrett- Connor E, Knowler WC (2010) Antidepressant medicine use and risk of developing diabetes during the diabetes prevention program and diabetes prevention program outcomes study. Diabetes Care 33(12):2549-2551
10. Khoza S, Barner JC (2011) Glucose dysregulation associated with antidepressant agents: An analysis of 17 published case reports. Int J Clin Pharm 33(3):484-492. doi:10.1007/s11096-011-9507-0
11. Knol MJ, Geelings MI, Egberts AC, Gorter KJ, Grobbee DE, Heerdink ER (2007) No increased incidence of diabetes in antidepressant users. Int Clin Psychopharmacol 22:282-286
12. Atlantis E, Browning C, Sims J, Kendig H (2009) Diabetes incidence associated with depression and antidepressants in the melbourne longitudinal studies on healthy ageing (melsha). Int J Geriatr Psychiatry 25:688-696
13. Knol M, Twisk J, Beekman A, Heine R, Snoek F, Pouwer F (2006) Depression as a risk factor for the onset of type 2 diabetes mellitus. A meta-analysis. Diabetologia 49(5):837-845
14. Eaton WW, Armenian H, Gallo J, Pratt L, Ford DE (1996) Depression and risk for onset of type ii diabetes. A prospective population-based study. Diabetes Care 19(10):1097-1102
15. Carnethon MR, Kinder LS, Fair JM, Stafford RS, Fortmann SP (2003) Symptoms of depression as a risk factor for incident diabetes: Findings from the national health and nutrition examination epidemiologic follow-up study, 1971-1992. Am J Epidemiol 158(5):416-423
16. Golden SH, Lazo M, Carnethon M, Bertoni AG, Schreiner PJ, Diez Roux AV, Lee HB, Lyketsos C (2008) Examining a bidirectional association between depressive symptoms and diabetes. JAMA 299(23):2751-2759
17. Demakakos P, Pierce MB, Hardy R (2010) Depressive symptoms and risk of type 2 diabetes in a national sample of middle-aged and older adults: The English longitudinal study of aging. Diabetes Care 33(4):792-797
18. Katon W (2010) Depression and diabetes: Unhealthy bedfellows. Depress Anxiety 27(4):323-326
19. Lyketsos CG (2010) Depression and diabetes: More on what the relationship might be. Am J Psychiatry 167(5):496-497
20. Centers for Disease Control and Prevention (2007) Diabetes fact sheet 2007. Available at: http://www.cdc.gov/diabetes/pubs/pdf/ ndfs-2007.pdf. Accessed 31 October 2009
21. Texas Health andHuman Services (2009) Texas medicaid and chip in perspective. Texas Health and Human Services. Available at: http:// www.hhsc.state.tx.us/medicaid/reports/PB7/PinkBookTOC.html. Accessed 4 Feb 2010
22. Patel NC, Crismon ML, Hoagwood K, Johnsrud MT, Rascati KL, Wilson JP, Jensen PS (2005) Trends in the use of typical and atypical antipsychotics in children and adolescents. J Am Acad Child Adolesc Psychiatry 44(6):548-556
23. Rascati KL, Stanford RH, Borker R (2005) A comparison of the risk of hospitalizations due to chronic obstructive pulmonary disease in medicaid patients with various medication regimens, including ipratropium, inhaled corticosteroids, salmeterol, or their combination. Clin Ther 27(3):346-354
24. Opolka JL, Rascati KL, Brown CM, Gibson PJ (2004) Ethnicity and prescription patterns for haloperidol, risperidone, and olanzapine. Psychiatr Serv 55(2):151-156
25. Smith MJ, Rascati KL, McWilliams BC (2004) Inhaled antiinflammatory pharmacotherapy and subsequent hospitalizations and emergency department visits among patients with asthma in the texas medicaid program. Ann Allergy Asthma Immunol 92(1):40-46
26. Barner JC, Worchel J, Yang M (2004) Frequency of new-onset diabetes mellitus and use of antipsychotic drugs among central texas veterans. Pharmacotherapy 24(11):1529-1538
27. YangM, Barner JC,Worchel J (2007) Factors related to antipsychotic oversupply among central texas veterans. Clin Ther 29(6):1214-1225
28. Etminan M, Streiner DL, Rochon PA (2003) Exploring the association between atypical neuroleptic agents and diabetes mellitus in older adults. Pharmacother 23(11):1411-1415
29. Sclar DA, Chin A, Skaer TL, Okamoto MP, Nakahiro RK, Gill MA (1991) Effect of health education in promoting prescription refill compliance among patients with hypertension. Clin Ther 13(4):489-495
30. Dailey G, Kim MS, Lian JF (2001) Patient compliance and persistence with antihyperglycemic drug regimens: evaluation of a medicaid patient population with type 2 diabetes mellitus. Clin Ther 23(8):1311-1320
31. Henderson DC, Cagliero E, Gray C, Nasrallah RA, Hayden DL, Schoenfeld DA, Goff DC (2000) Clozapine, diabetes mellitus, weight gain, and lipid abnormalities: A five-year naturalistic study. Am J Psychiatry 157(6):975-981
32. Luna B, Feinglos MN (2001) Drug-induced hyperglycemia. JAMA 286(16):1945-1948
33. Pandit MK, Burke J, Gustafson AB, Minocha A, Peiris AN (1993) Drug-induced disorders of glucose tolerance. Ann Intern Med 118 (7):529-539
34. Von Korff M, Wagner EH, Saunders K (1992) A chronic disease score from automated pharmacy data. J Clin Epidemiol 45 (2):197-203
35. Pan A, Sun Q, Okereke OI, Rexrode KM, Rubin RR, Lucas M, Willett WC, Manson JE, Hu FB (2011) Use of antidepressant medication and risk of type 2 diabetes: results from three cohorts of us adults. Diabetologia. doi:10.1007/s00125-011-2268-4
36. Derijks HJ, Meyboom RH, Heerdink ER, De Koning FH, Janknegt R, Lindquist M, Egberts AC (2008) The association between antidepressant use and disturbances in glucose homeostasis: evidence from spontaneous reports. Eur J Clin Pharmacol 64(5):531-538. doi:10.1007/s00228-007-0441-y[doi]
37. Chaouloff F, Laude D, BaudrieV(1990) Effects of the 5-ht1c/5-5-ht2 receptor agonists DOI and alpha-methyl-5-ht on plasma glucose and insulin levels in the rat. Eur J Pharmacol 187(3):435-443
38. Chaouloff F, Jeanrenaud B (1987) 5-ht1a and alpha-2 adrenergic receptors mediate the hyperglycemic and hypoinsulinemic effects of 8-hydroxy-2-(di-n- propylamino)tetralin in the conscious rat. J Pharmacol Exp Ther 243(3):1159-1166
39. Chaouloff F,Gunn SH,Young JB (1992) Central 5-hydroxytryptamine2 receptors are involved in the adrenal catecholamine-releasing and hyperglycemic effects of the 5-hydroxytryptamine indirect agonist Dfenfluramine in the conscious rat. J Pharmacol Exp Ther 260(3):1008-1016
40. Sugimoto Y, Inoue K, Yamada J (1999) Involvement of serotonin in zimelidine-induced hyperglycemia in mice. Biol Pharm Bull 22 (11):1240-1241
41. Carvalho F, Barros D, Silva J, Rezende E, Soares M, Fregoneze J, Silva EDE (2004) Hyperglycemia induced by acute central fluoxetine administration: role of the central CRH system and 5-ht3 receptors. Neuropeptides 38(2-3):98-105. doi:10.1016/j. npep.2004.04.004
42. Levkovitz Y, Ben-Shushan G, Hershkovitz A, Isaac R, Gil-Ad I, Shvartsman D, Ronen D, Weizman A, Zick Y (2007) Antidepressants induce cellular insulin resistance by activation of irs-1 kinases. Mol Cell Neurosci 36(3):305-312. doi:10.1016/j. mcn.2007.05.009
43. Erenmemisoglu A, Ozdogan UK, Saraymen R, Tutus A (1999) Effect of some antidepressants on glycaemia and insulin levels of normoglycaemic and alloxan-induced hyperglycaemic mice. J Pharm Pharmacol 51(6):741-743
44. Yamada J, Sugimoto Y, Inoue K (1999) Selective serotonin reuptake inhibitors fluoxetine and fluvoxamine induce hyperglycemia by different mechanisms. Eur J Pharmacol 382(3):211-215
45. Skene DJ, Bojkowski CJ, Arendt J (1994) Comparison of the effects of acute fluvoxamine and desipramine administration on melatonin and cortisol production in humans. Br J Clin Pharmacol 37(2):181-186
46. Centers for Disease Control and Prevention (2011) Diabetes fact sheet 2011. Available at: http://www.cdc.gov/diabetes/pubs/pdf/ ndfs-2011.pdf. Accessed 16 Feb 2011
47. Aitken M, Berndt ER, Cutler DM (2009) Prescription drug spending trends in the united states: looking beyond the turning point. Health Aff (Millwood) 28(1):w151-w160
48. Dall TM, Zhang Y, Chen YJ, Quick WW, Yang WG, Fogli J (2010) The economic burden of diabetes. Health Aff (Millwood) 29(2):297-303
49. Strom BL, Kimmel SE (2006) Textbook of pharmacoepidemiology. John Wiley & Sons, Chichester