Platelet-rich plasma in the management of articular cartilage pathology: A systematic review

Clinical Journal of Sport Medicine

Volumn 24, Issue 1, 2014, Pages 31-43

  Dold, Andrew P ^a   Zywiel, Michael G ^a   Taylor, Drew W ^b   Dwyer, Tim ^c   Theodoropoulos, John ^d  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c TORONTO WESTERN HOSPITAL   (Canada)

^d MOUNT SINAI HOSPITAL   (Canada)

Author keywords

microfracture; osteoarthritis; osteochondral defects; platelet rich plasma; sports medicine

Indexed keywords

HYALURONIC ACID;

ANKLE ARTHRITIS; ARTICULAR CARTILAGE; CHONDROPATHY; COMPARATIVE STUDY; DATA BASE; EMBASE; EVIDENCE BASED MEDICINE; FOLLOW UP; HIP OSTEOARTHRITIS; HUMAN; KNEE OSTEOARTHRITIS; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PUBLICATION; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SCORING SYSTEM; SYSTEMATIC REVIEW; THROMBOCYTE RICH PLASMA; WESTERN ONTARIO AND MCMASTER UNIVERSITIES OSTEOARTHRITIS INDEX;

CARTILAGE, ARTICULAR; HUMANS; KNEE INJURIES; OSTEOARTHRITIS, HIP; OSTEOARTHRITIS, KNEE; PLATELET-RICH PLASMA; TREATMENT OUTCOME;

EID: 84891861179     PISSN: 1050642X     EISSN: 15363724     Source Type: Journal    
DOI: 10.1097/01.jsm.0000432855.85143.e5     Document Type: Review

References (43)

1. Curl WW, Krome J, Gordon ES, et al. Cartilage injuries: a review of 31,516 knee arthroscopies. Arthroscopy. 1997;13:456-460. (Pubitemid 27344113)
2. Widuchowski W, Widuchowski J, Trzaska T. Articular cartilage defects: study of 25,124 knee arthroscopies. Knee. 2007;14:177-182. (Pubitemid 46695821)
3. Federico DJ, Lynch JK, Jokl P. Osteochondritis dissecans of the knee: a historical review of etiology and treatment. Arthroscopy. 1990;6:190-197. (Pubitemid 20295403)
4. van Dijk CN, Reilingh ML, Zengerink M, et al. The natural history of osteochondral lesions in the ankle. Instr Course Lect. 2010;59:375-386.
5. Detterline AJ, Goldstein JL, Rue JP, et al. Evaluation and treatment of osteochondritis dissecans lesions of the knee. J Knee Surg. 2008;21:106-115.
6. Kellett CF, Boscainos PJ, Gross AE. Surgical options for articular defects of the knee. Expert Rev Med Devices. 2006;3:585-593. (Pubitemid 44650448)
7. Buckwalter JA, Brown TD. Joint injury, repair, and remodeling: roles in post-traumatic osteoarthritis. Clin Orthop Relat Res. 2004;423:7-16. (Pubitemid 38787709)
8. Ochi M, Uchio Y, Kawasaki K, et al. Transplantation of cartilage-like tissue made by tissue engineering in the treatment of cartilage defects of the knee. J Bone Joint Surg Br. 2002;84:571-578. (Pubitemid 34578510)
9. Mankin HJ. The response of articular cartilage to mechanical injury. J Bone Joint Surg Am. 1982;64:460-466. (Pubitemid 12153547)
10. Buckwalter JA, Mankin HJ. Articular cartilage: tissue design and chondrocyte-matrix interactions. Instr Course Lect. 1998;47:477-486.
11. Smith GD, Knutsen G, Richardson JB. A clinical review of cartilage repair techniques. J Bone Joint Surg Br. 2005;87:445-449. (Pubitemid 40575762)
12. Furukawa T, Eyre DR, Koide S, et al. Biochemical studies on repair cartilage resurfacing experimental defects in the rabbit knee. J Bone Joint Surg Am. 1980;62:79-89. (Pubitemid 10146973)
13. Qi YY, Chen X, Jiang YZ, et al. Local delivery of autologous platelet in collagen matrix simulated in situ articular cartilage repair. Cell Transplant. 2009;18:1161-1169.
14. Sun Y, Feng Y, Zhang CQ, et al. The regenerative effect of platelet-rich plasma on healing in large osteochondral defects. Int Orthop. 2010;34: 589-597.
15. Saito M, Takahashi KA, Arai Y, et al. Intraarticular administration of platelet-rich plasma with biodegradable gelatin hydrogel microspheres prevents osteoarthritis progression in the rabbit knee. Clin Exp Rheumatol. 2009;27:201-207.
16. Milano G, Sanna Passino E, Deriu L, et al. The effect of platelet rich plasma combined with microfractures on the treatment of chondral defects: an experimental study in a sheep model. Osteoarthritis Cartilage. 2010;18:971-980.
17. Kon E, Filardo G, Delcogliano M, et al. Platelet autologous growth factors decrease the osteochondral regeneration capability of a collagenhydroxyapatite scaffold in a sheep model. BMC Musculoskelet Disord. 2010;11:220.
18. Akeda K, An HS, Okuma M, et al. Platelet-rich plasma stimulates porcine articular chondrocyte proliferation and matrix biosynthesis. Osteoarthritis Cartilage. 2006;14:1272-1280. (Pubitemid 44774435)
19. Kruger JP, Hondke S, Endres M, et al. Human platelet-rich plasma stimulates migration and chondrogenic differentiation of human subchondral progenitor cells. J Orthop Res. 2012;30:845-852.
20. Lee HR, Park KM, Joung YK, et al. Platelet-rich plasma loaded in situformed hydrogel enhances hyaline cartilage regeneration by CB1 upregulation. J Biomed Mater Res A. 2012;100:3099-3107.
21. Milano G, Deriu L, Sanna Passino E, et al. Repeated platelet concentrate injections enhance reparative response of microfractures in the treatment of chondral defects of the knee: an experimental study in an animal model. Arthroscopy. 2012;28:688-701.
22. Milano G, Deriu L, Sanna Passino E, et al. The effect of autologous conditioned plasma on the treatment of focal chondral defects of the knee. An experimental study. Int J Immunopathol Pharmacol. 2011;24:117-124.
23. Dhollander AAM, De Neve F, Almqvist KF, et al. Autologous matrixinduced chondrogenesis combined with platelet-rich plasma gel: technical description and a five pilot patients report. Knee Surg Sports Traumatol Arthrosc. 2011;19:536-542.
24. Filardo G, Kon E, Buda R, et al. Platelet-rich plasma intra-articular knee injections for the treatment of degenerative cartilage lesions and osteoarthritis. Knee Surg Sports Traumatol Arthrosc. 2011;19:528-535.
25. Kon E, Buda R, Filardo G, et al. Platelet-rich plasma: intra-articular knee injections produced favorable results on degenerative cartilage lesions. Knee Surg Sports Traumatol Arthrosc. 2010;18:472-479.
26. Kon E, Mandelbaum B, Buda R, et al. Platelet-rich plasma intra-articular injection versus hyaluronic acid viscosupplementation as treatments for cartilage pathology: from early degeneration to osteoarthritis. Arthroscopy. 2011;27:1490-1501.
27. Mei-Dan O, Carmont MR, Laver L, et al. Platelet-rich plasma or hyaluronate in the management of osteochondral lesions of the talus. Am J Sports Med. 2012;40:534-541.
28. Sampson S, Reed M, Silvers H, et al. Injection of platelet-rich plasma in patients with primary and secondary knee osteoarthritis: a pilot study. Am J Phys Med Rehabil. 2010;89:961-969.
29. Sanchez M, Anitua E, Azofra J, et al. Intra-articular injection of an autologous preparation rich in growth factors for the treatment of knee OA: a retrospective cohort study. Clin Exp Rheumatol. 2008;26:910-913.
30. Sanchez M, Guadilla J, Fiz N, et al. Ultrasound-guided platelet-rich plasma injections for the treatment of osteoarthritis of the hip. Rheumatology (Oxford). 2012;51:144-150.
31. Siclari A, Mascaro G, Gentili C, et al. A cell-free scaffold-based cartilage repair provides improved function hyaline-like repair at one year. Clin Orthop Relat Res. 2012;470:910-919.
32. Spakova T, Rosocha J, Lacko M, et al. Treatment of knee joint osteoarthritis with autologous platelet-rich plasma in comparison with hyaluronic acid. Am J Phys Med Rehabil. 2012;91:411-417.
33. Wang-Saegusa A, Cugat R, Ares O, et al. Infiltration of plasma rich in growth factors for osteoarthritis of the knee short-term effects on function and quality of life. Arch Orthop Trauma Surg. 2011;131:311-317.
34. Higgins JP, Altman DG, Gotzsche PC, et al. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ. 2011;343: d5928.
35. Landesberg R, Roy M, Glickman RS. Quantification of growth factor levels using a simplified method of platelet-rich plasma gel preparation. J Oral Maxillofac Surg. 2000;58:297-300; discussion, 300-301. (Pubitemid 30129867)
36. Zimmermann R, Reske S, Metzler P, et al. Preparation of highly concentrated and white cell-poor platelet-rich plasma by plateletpheresis. Vox Sang. 2008;95:20-25. (Pubitemid 351799420)
37. Anitua E. The use of plasma-rich growth factors (PRGF) in oral surgery. Pract Proced Aesthet Dent. 2001;13:487-493.
38. Daugherty K, Porucznik MA. Platelet-rich plasma: what's behind the hype? In: Terry Canale ST, ed. AAOS Now. Rosemont, IL: American Academy of Orthopaedic Surgeons; 2011.
39. Sanchez M, Anitua E, Orive G, et al. Platelet-rich therapies in the treatment of orthopaedic sport injuries. Sports Med. 2009;39:345-354.
40. Taylor DW, Petrera M, Hendry M, et al. A systematic review of the use of platelet-rich plasma in sports medicine as a new treatment for tendon and ligament injuries. Clin J Sport Med. 2011;21:344-352.
41. Easterbrook PJ, Berlin JA, Gopalan R, et al. Publication bias in clinical research. Lancet. 1991;337:867-872.
42. Rutjes AW, Juni P, da Costa BR, et al. Viscosupplementation for osteoarthritis of the knee: a systematic review and meta-analysis. Ann Intern Med. 2012;157:180-191.
43. Loveday D, Clifton R, Robinson A. Interventions for treating osteochondral defects of the talus in adults. Cochrane Database Syst Rev. 2010;8: CD008104.