Autologous matrix-induced chondrogenesis combined with platelet-rich plasma gel: Technical description and a five pilot patients report

Knee Surgery, Sports Traumatology, Arthroscopy

Volumn 19, Issue 4, 2011, Pages 536-542

  Dhollander, A A M ^a   de Neve, F ^a   Almqvist, K F ^a   Verdonk, R ^a   Lambrecht, S ^a   Elewaut, D ^a   Verbruggen, G ^a   Verdonk, P C M ^a,b  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b Stedelijk Ziekenhuis Roeselare   (Belgium)

Author keywords

AMIC; Cartilage; Knee; PRP

Indexed keywords

COLLAGEN;

ADULT; ARTICLE; ARTICULAR CARTILAGE; AUTOTRANSPLANTATION; CHONDROGENESIS; EPIDEMIOLOGY; FEMALE; FOLLOW UP; GEL; HUMAN; KNEE INJURY; MALE; METHODOLOGY; MIDDLE AGED; MULTIMODALITY CANCER THERAPY; PAIN ASSESSMENT; PATELLA; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PILOT STUDY; PROSPECTIVE STUDY; SUTURING METHOD; THROMBOCYTE RICH PLASMA; TISSUE ENGINEERING; TREATMENT OUTCOME;

ADULT; CARTILAGE, ARTICULAR; CHONDROGENESIS; COLLAGEN; COMBINED MODALITY THERAPY; FEMALE; FOLLOW-UP STUDIES; GELS; HUMANS; KNEE INJURIES; MALE; MIDDLE AGED; PAIN MEASUREMENT; PATELLA; PILOT PROJECTS; PLATELET-RICH PLASMA; PROSPECTIVE STUDIES; SAMPLING STUDIES; SUTURE TECHNIQUES; TISSUE ENGINEERING; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 79952988319     PISSN: 09422056     EISSN: 14337347     Source Type: Journal    
DOI: 10.1007/s00167-010-1337-4     Document Type: Article

References (36)

1. Behrens P, Bitter T, Kurz B, Russlies M (2006) Matrix-associated autologous chondrocyte transplantation/implantation (MACT/MACI)-5-year follow-up. Knee 13: 194-202.
2. Bekkers JE, de Windt TS, Raijmakers NJ, Dhert WJ, Saris DB (2009) Validation of the knee injury and osteoarthritis outcome score (KOOS) for the treatment of focal cartilage lesions. Osteoarthr Cartil 17: 1434-1439.
3. Benthien JP, Behrens P (2010) Autologous matrix-induced chondrogenesis (AMIC) combining microfracturing and a collagen I/III matrix for articular cartilage resurfacing. Cartilage 1: 65-68.
4. Bijur PE, Silver W, Gallagher EJ (2001) Reliability of the visual analog scale for measurement of acute pain. Acad Emerg Med 8: 1153-1157.
5. Buckwalter JA, Lane NE (1997) Athletics and osteoarthritis. Am J Sports Med 25: 873-881.
6. Cerynik DL, Lewullis GE, Joves BC, Palmer MP, Tom JA (2009) Outcomes of microfracture in professional basketball players. Knee Surg Sports Traumatol Arthrosc 17: 1135-1139.
7. Dhollander AAM, Huysse WCJ, Almqvist KF, Verdonk PCM, Verstraete KL, Verdonk R, Verbruggen G (2010) MRI evaluation of a new scaffold-based allogenic chondrocyte implantation for cartilage repair. Eur J Radiol 75: 72-81.
8. Dorotka R, Windberger U, Macfelda K, Bindreiter U, Toma C, Nehrer S (2005) Repair of articular cartilage defects treated by microfracture and a three-dimensional collagen matrix. Biomaterials 26: 3617-3629.
9. Farr J (2007) Autologous chondrocyte implantation improves patellofemoral cartilage treatment outcomes. Clin Orthop Relat Res 463: 187-194.
10. Gallaher EJ, Bijur PE, Laimer C, Silver W (2002) Reliability and validity of a visual analog scale for acute abdominal pain in the ED. Am J Emerg Med 20: 287-290.
11. Gille J, Meisner U, Ehlers EM, Muller A, Russlies M, Behrens P (2005) Migration pattern, morphology and viability of cells suspended in or sealed with fibrin glue: a histomorphologic study. Tissue Cell 37: 339-348.
12. Gille J, Schuseil E, Wimmer J, Gellissen J, Schulz AP, Behrens P (2010) Mid-term results of autologous matrix-induced chondrogenesis for treatment of focal cartilage defects in the knee. Knee Surg Sports Traumatol Arthrosc 18: 1456-1464.
13. Gobbi A, Kon E, Berruto M, Francisco R, Filardo G, Marcacci M (2006) Patellofemoral full-thickness chondral defects treated with Hyalograft-C: a clinical, arthroscopic, and histologic review. Am J Sports Med 34: 1763-1773.
14. Hjelle K, Soljeim E, Strand T, Muri R, Brittberg M (2002) Articular cartilage defects in 1, 000 knee arthroscopies. Arthroscopy 18: 730-734.
15. Knutsen G, Drogset JO, Engebretsen L, Grontvedt T, Isaksen V, Ludvigsen TC, Roberts S, Solheim E, Strand T, Johansen O (2007) A randomized trial comparing autologous chondrocyte implantation with microfracture. Findings at five years. J Bone Joint Surg Am 89: 2105-2112.
16. Kreuz PC, Steinwachs M, Erggelet C, Krause SJ, Ossendorf C, Maier D, Ghanem N, Uhl M, Haag M (2007) Classification of graft hypertrophy after autologous chondrocyte implantation of full-thickness chondral defects in the knee. Osteoarthritis Cart 15: 1339-1347.
17. Kujala UM, Jaakkola LH, Koskinen SK, Taimela S, Hurme M, Nelimarkka O (1993) Scoring of patellofemoral disorders. Arthroscopy 9: 159-163.
18. Lopez-Vidriero E, Goulding KA, Simon DA, Sanchez M, Johnson DH (2010) The use of platelet-rich plasma in arthroscopy and sports medicine: optimizing the healing environment. Arthroscopy 26: 269-278.
19. Marlovits S, Singer P, Zeller P, Mandl I, Haller J, Trattning S (2006) Magnetic resonance observation of cartilage repair tissue (MOCART) for the evaluation of autologous chondrocyte transplantation: determination of interobserver variability and correlation to clinical outcome after 2 years. Eur J Radiol 57: 16-23.
20. Marlovits S, Striessnig G, Resinger CT, Aldrian SM, Vecsei V, Imhof H, Trattnig S (2004) Definition of pertinent parameters for the evaluation of articular cartilage repair tissue with high-resolution magnetic resonance imaging. Eur J Radiol 52: 310-319.
21. Milano G, Passino ES, Deriu L, Careddu G, Manunta L, Manunta A, Saccomanno MF, Fabbriciani C (2010) The effect of platelet rich plasma combined with microfractures on the treatment of chondral defects. An experimental study in a sheep model. Osteoarthr Cartil 18: 971-980.
22. Minas T, Bryant T (2005) The role of autologous chondrocyte implantation in the patellofemoral joint. Clin Orthop Relat Res 436: 30-39.
23. Nehrer S, Breinan HA, Ramappa A, Shortkroff S, Young G, Minas T, Sledge CB, Yannas IV, Spector M (1997) Canine chondrocytes seeded in type I and type II collagen implants investigated in vitro. J Biomed Mater Res 38: 95-104.
24. Niemeyer P, Steinwachs M, Erggelet C, Kreuz PC, Kraft N, Köstler W, Mehlhorn A, Südkam NP (2008) Autologous chondrocyte implantation for the treatment of retropatellar cartilage defects: clinical results referred to defect localisation. Arch Orthop Trauma Surg 128: 1223-1231.
25. Niemeyer P, Petska JM, Kreuz PC, Erggelet C, Schmal H, Suedkamp NP, Steinwachs M (2008) Characteristic complications after autologous chondrocyte implantation for cartilage defects of the knee joint. Am J Sports Med 36: 2091-2099.
26. Pascual-Garrido C, Slabaugh MA, L'Heureux DR, Friel NA, Cole BJ (2009) Recommendations and treatment outcomes for patellofemoral articular cartilage defects with autologous chondrocyte implantation: prospective evaluation at average 4-year follow-up. Am J Sports Med 37: 33-41.
27. Peterson L, Minas T, Brittberg M, Nilsson A, Sjogren-Jansson E, Lindahl A (2000) Two- to 9-year outcome after autologous chondrocyte transplantation of the knee. Clin Orthop Relat Res 374: 212-234.
28. Roos EM, Roos HP, Ekdahl C, Lohmander LS (1998) Knee injury and osteoarthritis outcome score (KOOS): validation of a Swedish version. Scand J Med Sci Sports 8: 439-448.
29. Roos EM, Roos HP, Lohmander LS, Ekdahl C, Beynnon BD (1998) Knee injury and osteoarthritis outcome score (KOOS): development of a self-administered outcome measure. J Orthop Sports Phys Ther 28: 88-96.
30. Roos EM, Toksvig-Larsen S (2003) Knee injury and osteoarthritis outcome score (KOOS): validation and comparison to the WOMAC in total knee replacement. Health Qual Life Outcomes 1: 17.
31. Russlies M, Behrens P, Ehlers EM, Brohl C, Vindigni C, Spector M, Kurz B (2005) Periosteum stimulates subchondral bone densification in autologous chondrocyte transplantation in a sheep model. Cell Tissue Res 319: 133-142.
32. Saris DBF, Vanlauwe J, Victor J, Almqvist KF, Verdonk R, Bellemans J, Luyten FP (2009) Treatment of symptomatic cartilage defects of the knee: characterized chondrocyte implantation results in better clinical outcome at 36 months in a randomized trial compared to microfracture. Am J Sports Med 37: 10-19.
33. Shapiro F, Koide S, Glimcher MJ (1993) Cell origin and differentiation in the repair of full-thickness defects of articular cartilage. J Bone Joint Surg Am 75: 532-553.
34. Steadman JR, Rodkey WG, Briggs KK (2002) Microfracture to treat full-thickness chondral defects: surgical technique, rehabilitation, and outcomes. J Knee Surg 15: 170-176.
35. Tegner Y (1985) Cruciate ligament injuries in the knee: evaluation and rehabilitation [dissertation]. Linköping University, Linköping.
36. Tegner Y, Lysholm J (1985) Rating systems in the evaluation of knee ligament injuries. Clin Orthop 198: 43-49.