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Volumn 25, Issue 2, 2014, Pages 147-152

Six weeks of voluntary exercise don't protect C57BL/6 mice against neurotoxicity of MPTP and MPP+

Author keywords

Amphetamine; Dopamine; Dopamine transporter; Mitochondria; Neuroprotection; Parkinson's disease

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

EID: 84891859336     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-013-9412-5     Document Type: Article
Times cited : (22)

References (35)
  • 1
    • 34848867164 scopus 로고    scopus 로고
    • Mitochondrial IV complex and brain neurothrophic derived factor responses of mice brain cortex after downhill training
    • DOI 10.1016/j.neulet.2007.08.058, PII S0304394007009457
    • Aguiar AS Jr, Tuon T, Pinho CA, Silva LA, Andreazza AC, Kapczinski F, Quevedo J, Streck EL, Pinho RA (2007) Mitochondrial IV complex and brain neurothrophic derived factor responses of mice brain cortex after downhill training. Neurosci Lett 426(3):171-174 (Pubitemid 47500183)
    • (2007) Neuroscience Letters , vol.426 , Issue.3 , pp. 171-174
    • Aguiar Jr., A.S.1    Tuon, T.2    Pinho, C.A.3    Silva, L.A.4    Andreazza, A.C.5    Kapczinski, F.6    Quevedo, J.7    Streck, E.L.8    Pinho, R.A.9
  • 2
    • 41049103479 scopus 로고    scopus 로고
    • The effect of n-acetylcysteine and deferoxamine on exercise-induced oxidative damage in striatum and hippocampus of mice
    • DOI 10.1007/s11064-007-9485-8
    • Aguiar AS Jr, Tuon T, Soares FS, da Rocha LG, Silveira PC, Pinho RA (2008) The effect of n-acetylcysteine and deferoxamine on exercise-induced oxidative damage in striatum and hippocampus of mice. Neurochem Res 33(5):729-736 (Pubitemid 351423137)
    • (2008) Neurochemical Research , vol.33 , Issue.5 , pp. 729-736
    • Aguiar Jr., A.S.1    Tuon, T.2    Soares, F.S.3    Da Rocha, L.G.C.4    Silveira, P.C.5    Pinho, R.A.6
  • 3
    • 67449141646 scopus 로고    scopus 로고
    • Physical exercise improves motor and short-term social memory deficits in reserpinized rats
    • 10.1016/j.brainresbull.2009.05.005 1:CAS:528:DC%2BD1MXnvVWqt7g%3D 19463920 10.1016/j.brainresbull.2009.05.005
    • Aguiar AS Jr, Araujo AL, da-Cunha TR, Speck AE, Ignacio ZM, De-Mello N, Prediger RD (2009) Physical exercise improves motor and short-term social memory deficits in reserpinized rats. Brain Res Bull 79(6):452-457. doi: 10.1016/j.brainresbull.2009.05.005
    • (2009) Brain Res Bull , vol.79 , Issue.6 , pp. 452-457
    • Aguiar, Jr.A.S.1    Araujo, A.L.2    Da-Cunha, T.R.3    Speck, A.E.4    Ignacio, Z.M.5    De-Mello, N.6    Prediger, R.D.7
  • 4
    • 84855902010 scopus 로고    scopus 로고
    • Short bouts of mild-intensity physical exercise improve spatial learning and memory in aging rats: Involvement of hippocampal plasticity via AKT, CREB and BDNF signaling
    • 1:CAS:528:DC%2BC3MXhs1Cqt7bP 21983475 10.1016/j.mad.2011.09.005
    • Aguiar AS Jr, Castro AA, Moreira EL, Glaser V, Santos AR, Tasca CI, Latini A, Prediger RD (2011) Short bouts of mild-intensity physical exercise improve spatial learning and memory in aging rats: involvement of hippocampal plasticity via AKT, CREB and BDNF signaling. Mech Ageing Dev 132(11-12):560-567
    • (2011) Mech Ageing Dev , vol.132 , Issue.11-12 , pp. 560-567
    • Aguiar, Jr.A.S.1    Castro, A.A.2    Moreira, E.L.3    Glaser, V.4    Santos, A.R.5    Tasca, C.I.6    Latini, A.7    Prediger, R.D.8
  • 6
    • 84879798142 scopus 로고    scopus 로고
    • Parkin-Knockout Mice did not Display Increased Vulnerability to Intranasal Administration of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)
    • 1:CAS:528:DC%2BC3sXhtVeit77F 23588969 10.1007/s12640-013-9389-0
    • Aguiar AS Jr, Tristao FS, Amar M, Chevarin C, Lanfumey L, Mongeau R, Corti O, Prediger RD, Raisman-Vozari R (2013b) Parkin-Knockout Mice did not Display Increased Vulnerability to Intranasal Administration of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP). Neurotox Res 24(2):280-287
    • (2013) Neurotox Res , vol.24 , Issue.2 , pp. 280-287
    • Aguiar, Jr.A.S.1    Tristao, F.S.2    Amar, M.3    Chevarin, C.4    Lanfumey, L.5    Mongeau, R.6    Corti, O.7    Prediger, R.D.8    Raisman-Vozari, R.9
  • 7
    • 0026598930 scopus 로고
    • Irreversible inhibition of mitochondrial complex i by 1-methyl-4-phenylpyridinium: Evidence for free radical involvement
    • 1:CAS:528:DyaK38XhtVSktb4%3D 1729421 10.1111/j.1471-4159.1992.tb09789.x
    • Cleeter MW, Cooper JM, Schapira AH (1992) Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement. J Neurochem 58(2):786-789
    • (1992) J Neurochem , vol.58 , Issue.2 , pp. 786-789
    • Cleeter, M.W.1    Cooper, J.M.2    Schapira, A.H.3
  • 8
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: Mechanisms and models
    • DOI 10.1016/S0896-6273(03)00568-3
    • Dauer W, Przedborski S (2003) Parkinson's disease: mechanisms and models. Neuron 39(6):889-909 (Pubitemid 37130207)
    • (2003) Neuron , vol.39 , Issue.6 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 9
    • 3242795769 scopus 로고    scopus 로고
    • Exercise-induced behavioral recovery and neuroplasticity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse basal ganglia
    • DOI 10.1002/jnr.20162
    • Fisher BE, Petzinger GM, Nixon K, Hogg E, Bremmer S, Meshul CK, Jakowec MW (2004) Exercise-induced behavioral recovery and neuroplasticity in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-lesioned mouse basal ganglia. J Neurosci Res 77(3):378-390 (Pubitemid 38970982)
    • (2004) Journal of Neuroscience Research , vol.77 , Issue.3 , pp. 378-390
    • Fisher, B.E.1    Petzinger, G.M.2    Nixon, K.3    Hogg, E.4    Bremmer, S.5    Meshul, C.K.6    Jakowec, M.W.7
  • 10
    • 80051615232 scopus 로고    scopus 로고
    • Running wheel activity restores MPTP-induced functional deficits
    • 1:CAS:528:DC%2BC3MXjsFyqsbk%3D 20852902 10.1007/s00702-010-0474-8
    • Fredriksson A, Stigsdotter IM, Hurtig A, Ewalds-Kvist B, Archer T (2011) Running wheel activity restores MPTP-induced functional deficits. J Neural Transm 118(3):407-420
    • (2011) J Neural Transm , vol.118 , Issue.3 , pp. 407-420
    • Fredriksson, A.1    Stigsdotter, I.M.2    Hurtig, A.3    Ewalds-Kvist, B.4    Archer, T.5
  • 11
    • 77953104126 scopus 로고    scopus 로고
    • Exercise protects against MPTP-induced neurotoxicity in mice
    • 1:CAS:528:DC%2BC3cXntlaks78%3D 20116369 10.1016/j.brainres.2010.01.053
    • Gerecke KM, Jiao Y, Pani A, Pagala V, Smeyne RJ (2010) Exercise protects against MPTP-induced neurotoxicity in mice. Brain Res 1341:72-83
    • (2010) Brain Res , vol.1341 , pp. 72-83
    • Gerecke, K.M.1    Jiao, Y.2    Pani, A.3    Pagala, V.4    Smeyne, R.J.5
  • 12
    • 84865092868 scopus 로고    scopus 로고
    • Exercise does not protect against MPTP-induced neurotoxicity in BDNF happloinsufficent mice
    • 1:CAS:528:DC%2BC38Xht1CnsbjP 3422268 22912838 10.1371/journal.pone. 0043250
    • Gerecke KM, Jiao Y, Pagala V, Smeyne RJ (2012) Exercise does not protect against MPTP-induced neurotoxicity in BDNF happloinsufficent mice. PLoS One 7(8):e43250
    • (2012) PLoS One , vol.7 , Issue.8 , pp. 43250
    • Gerecke, K.M.1    Jiao, Y.2    Pagala, V.3    Smeyne, R.J.4
  • 13
    • 0030071106 scopus 로고    scopus 로고
    • Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
    • DOI 10.1038/379606a0
    • Giros B, Jaber M, Jones SR, Wightman RM, Caron MG (1996) Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379(6566):606-612 (Pubitemid 26052818)
    • (1996) Nature , vol.379 , Issue.6566 , pp. 606-612
    • Giros, B.1    Jaber, M.2    Jones, S.R.3    Wightman, R.M.4    Caron, M.G.5
  • 14
    • 84984550880 scopus 로고    scopus 로고
    • Effects of inorganic selenium administration in methylmercury-induced neurotoxicity in mouse cerebral cortex
    • 1:CAS:528:DC%2BC3cXhtFCrt73K 20620206 10.1016/j.ijdevneu.2010.07.225
    • Glaser V, Nazari EM, Muller YM, Feksa L, Wannmacher CM, Rocha JB, de Bem AF, Farina M, Latini A (2010) Effects of inorganic selenium administration in methylmercury-induced neurotoxicity in mouse cerebral cortex. Int J Dev Neurosci 28(7):631-637
    • (2010) Int J Dev Neurosci , vol.28 , Issue.7 , pp. 631-637
    • Glaser, V.1    Nazari, E.M.2    Muller, Y.M.3    Feksa, L.4    Wannmacher, C.M.5    Rocha, J.B.6    De Bem, A.F.7    Farina, M.8    Latini, A.9
  • 15
    • 84861917566 scopus 로고    scopus 로고
    • Reactive species can pose special problems needing special solutions: Some examples
    • Oxford (eds) 4 Oxford New York
    • Halliwell B, Gutteridge JM (2007) Reactive species can pose special problems needing special solutions: some examples. In: Oxford (ed) Free radicals in biology and medicine, 4th edn. Oxford, New York, pp 341-394
    • (2007) Free Radicals in Biology and Medicine , pp. 341-394
    • Halliwell, B.1    Gutteridge, J.M.2
  • 16
    • 0021155228 scopus 로고
    • MPTP-induced parkinsonism in human and non-human primates - Clinical and experimental aspects
    • Langston JW, Langston EB, Irwin I (1984) MPTP-induced parkinsonism in human and non-human primates-clinical and experimental aspects. Acta Neurol Scand Suppl 100:49-54 (Pubitemid 14060412)
    • (1984) Acta Neurologica Scandinavica , vol.70 , Issue.SUPPL. 100 , pp. 49-54
    • Langston, J.W.1    Langston, E.B.2    Irwin, I.3
  • 17
    • 79953292347 scopus 로고    scopus 로고
    • Neuroprotective effects and mechanisms of exercise in a chronic mouse model of Parkinson's disease with moderate neurodegeneration
    • 3079264 21375602 10.1111/j.1460-9568.2011.07626.x
    • Lau YS, Patki G, Das-Panja K, Le WD, Ahmad SO (2011) Neuroprotective effects and mechanisms of exercise in a chronic mouse model of Parkinson's disease with moderate neurodegeneration. Eur J Neurosci 33(7):1264-1274
    • (2011) Eur J Neurosci , vol.33 , Issue.7 , pp. 1264-1274
    • Lau, Y.S.1    Patki, G.2    Das-Panja, K.3    Le, W.D.4    Ahmad, S.O.5
  • 18
    • 71849104860 scopus 로고
    • Protein measurement with the Folin phenol reagent
    • 1:CAS:528:DyaG38XhsVyrsw%3D%3D 14907713
    • Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193(1):265-275
    • (1951) J Biol Chem , vol.193 , Issue.1 , pp. 265-275
    • Lowry, O.H.1    Rosebrough, N.J.2    Farr, A.L.3    Randall, R.J.4
  • 19
    • 0030473215 scopus 로고    scopus 로고
    • Development of novel, potent, and selective dopamine reuptake inhibitors through alteration of the piperazine ring of 1-[2-(diphenylmethoxy)ethyl]- and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909)
    • DOI 10.1021/jm960305h
    • Matecka D, Rothman RB, Radesca L, de Costa BR, Dersch CM, Partilla JS, Pert A, Glowa JR, Wojnicki FH, Rice KC (1996) Development of novel, potent, and selective dopamine reuptake inhibitors through alteration of the piperazine ring of 1-[2-(diphenylmethoxy)ethyl]-and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4- (3-phenylpropyl)piperazines (GBR 12935 and GBR 12909). J Med Chem 39(24):4704-4716 (Pubitemid 26423888)
    • (1996) Journal of Medicinal Chemistry , vol.39 , Issue.24 , pp. 4704-4716
    • Matecka, D.1    Rothman, R.B.2    Radesca, L.3    De Costa, B.R.4    Dersch, C.M.5    Partilia, J.S.6    Pert, A.7    Glowa, J.R.8    Wojnicki, F.H.E.9    Rice, K.C.10
  • 23
    • 33845796526 scopus 로고    scopus 로고
    • Running wheel exercise enhances recovery from nigrostriatal dopamine injury without inducing neuroprotection
    • DOI 10.1016/j.neuroscience.2006.10.042, PII S0306452206014680
    • O'Dell SJ, Gross NB, Fricks AN, Casiano BD, Nguyen TB, Marshall JF (2007) Running wheel exercise enhances recovery from nigrostriatal dopamine injury without inducing neuroprotection. Neuroscience 144(3):1141-1151 (Pubitemid 46014003)
    • (2007) Neuroscience , vol.144 , Issue.3 , pp. 1141-1151
    • O'Dell, S.J.1    Gross, N.B.2    Fricks, A.N.3    Casiano, B.D.4    Nguyen, T.B.5    Marshall, J.F.6
  • 26
    • 60749100350 scopus 로고    scopus 로고
    • Restorative effect of endurance exercise on behavioral deficits in the chronic mouse model of Parkinson's disease with severe neurodegeneration
    • 2640401 19154608 10.1186/1471-2202-10-6
    • Pothakos K, Kurz MJ, Lau YS (2009) Restorative effect of endurance exercise on behavioral deficits in the chronic mouse model of Parkinson's disease with severe neurodegeneration. BMC Neurosci 10:6
    • (2009) BMC Neurosci , vol.10 , pp. 6
    • Pothakos, K.1    Kurz, M.J.2    Lau, Y.S.3
  • 28
    • 84874763983 scopus 로고    scopus 로고
    • BDNF receptor blockade hinders the beneficial effects of exercise in a rat model of Parkinson's disease
    • 1:CAS:528:DC%2BC3sXksFOrsL4%3D 23396085 10.1016/j.neuroscience.2013.01. 060
    • Real CC, Ferreira AF, Chaves-Kirsten GP, Torrao AS, Pires RS, Britto LR (2013) BDNF receptor blockade hinders the beneficial effects of exercise in a rat model of Parkinson's disease. Neuroscience 237:118-129
    • (2013) Neuroscience , vol.237 , pp. 118-129
    • Real, C.C.1    Ferreira, A.F.2    Chaves-Kirsten, G.P.3    Torrao, A.S.4    Pires, R.S.5    Britto, L.R.6
  • 30
    • 0025254401 scopus 로고
    • Mitochondrial complex i deficiency in Parkinson's disease
    • 1:CAS:528:DyaK3cXhsFKiur4%3D 2154550 10.1111/j.1471-4159.1990.tb02325.x
    • Schapira AH, Cooper JM, Dexter D, Clark JB, Jenner P, Marsden CD (1990) Mitochondrial complex I deficiency in Parkinson's disease. J Neurochem 54(3):823-827
    • (1990) J Neurochem , vol.54 , Issue.3 , pp. 823-827
    • Schapira, A.H.1    Cooper, J.M.2    Dexter, D.3    Clark, J.B.4    Jenner, P.5    Marsden, C.D.6
  • 31
    • 0033749345 scopus 로고    scopus 로고
    • MPTP susceptibility in the mouse: Behavioral, neurochemical, and histological analysis of gender and strain differences
    • 1:STN:280:DC%2BD3M7gvFyhug%3D%3D 11105391 10.1023/A:1001958023096
    • Sedelis M, Hofele K, Auburger GW, Morgan S, Huston JP, Schwarting RK (2000) MPTP susceptibility in the mouse: behavioral, neurochemical, and histological analysis of gender and strain differences. Behav Genet 30(3):171-182
    • (2000) Behav Genet , vol.30 , Issue.3 , pp. 171-182
    • Sedelis, M.1    Hofele, K.2    Auburger, G.W.3    Morgan, S.4    Huston, J.P.5    Schwarting, R.K.6
  • 32
    • 79953908283 scopus 로고    scopus 로고
    • Effects of treadmill exercise on behavioral recovery and neural changes in the substantia nigra and striatum of the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-lesioned mouse
    • 1:CAS:528:DC%2BC3MXksFejtLk%3D 3073026 21315689 10.1016/j.brainres.2011. 02.003
    • Smith BA, Goldberg NR, Meshul CK (2011) Effects of treadmill exercise on behavioral recovery and neural changes in the substantia nigra and striatum of the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-lesioned mouse. Brain Res 1386:70-80
    • (2011) Brain Res , vol.1386 , pp. 70-80
    • Smith, B.A.1    Goldberg, N.R.2    Meshul, C.K.3
  • 33
    • 84870291915 scopus 로고    scopus 로고
    • Treadmill exercise ameliorates dopaminergic neuronal loss through suppressing microglial activation in Parkinson's disease mice
    • 1:CAS:528:DC%2BC38XhsF2msrjN 23069581 10.1016/j.lfs.2012.10.003
    • Sung YH, Kim SC, Hong HP, Park CY, Shin MS, Kim CJ, Seo JH, Kim DY, Kim DJ, Cho HJ (2012) Treadmill exercise ameliorates dopaminergic neuronal loss through suppressing microglial activation in Parkinson's disease mice. Life Sci 91(25-26):1309-1316
    • (2012) Life Sci , vol.91 , Issue.25-26 , pp. 1309-1316
    • Sung, Y.H.1    Kim, S.C.2    Hong, H.P.3    Park, C.Y.4    Shin, M.S.5    Kim, C.J.6    Seo, J.H.7    Kim, D.Y.8    Kim, D.J.9    Cho, H.J.10
  • 34
    • 0012849885 scopus 로고    scopus 로고
    • Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease
    • DOI 10.1016/S0306-4522(03)00096-4
    • Tillerson JL, Caudle WM, Reveron ME, Miller GW (2003) Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease. Neuroscience 119(3):899-911 (Pubitemid 36694814)
    • (2003) Neuroscience , vol.119 , Issue.3 , pp. 899-911
    • Tillerson, J.L.1    Caudle, W.M.2    Reveron, M.E.3    Miller, G.W.4
  • 35
    • 77955161623 scopus 로고    scopus 로고
    • Physical activities and future risk of Parkinson disease
    • 1:STN:280:DC%2BC3cjgt1OltA%3D%3D 20660864 10.1212/WNL.0b013e3181ea1597
    • Xu Q, Park Y, Huang X, Hollenbeck A, Blair A, Schatzkin A, Chen H (2010) Physical activities and future risk of Parkinson disease. Neurology 75(4):341-348
    • (2010) Neurology , vol.75 , Issue.4 , pp. 341-348
    • Xu, Q.1    Park, Y.2    Huang, X.3    Hollenbeck, A.4    Blair, A.5    Schatzkin, A.6    Chen, H.7


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