메뉴 건너뛰기




Volumn 26, Issue 1, 2014, Pages 27-33

Updates on the treatment of human epidermal growth factor receptor type 2-positive breast cancer

Author keywords

Breast cancer; Her2; lapatinib; pertuzumab; trastuzumab

Indexed keywords

BIOLOGICAL MARKER; CAPECITABINE; CARBOPLATIN; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIRUBICIN; ESTROGEN RECEPTOR; EVEROLIMUS; LAPATINIB; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; NAVELBINE; NEW DRUG; PACLITAXEL; PERTUZUMAB; TRASTUZUMAB; TRASTUZUMAB EMTANSINE;

EID: 84891853962     PISSN: 1040872X     EISSN: 1473656X     Source Type: Journal    
DOI: 10.1097/GCO.0000000000000043     Document Type: Review
Times cited : (8)

References (33)
  • 2
    • 84873918443 scopus 로고    scopus 로고
    • Activating HER2 mutations in HER2 gene amplification negative breast cancer
    • Bose R, Kavuri SM, Searleman AC, et al. Activating HER2 mutations in HER2 gene amplification negative breast cancer. Cancer Discov 2013; 3:224-237
    • (2013) Cancer Discov , vol.3 , pp. 224-237
    • Bose, R.1    Kavuri, S.M.2    Searleman, A.C.3
  • 3
    • 84873993908 scopus 로고    scopus 로고
    • Current approaches and future directions in the treatment of HER2-positive breast cancer
    • Hurvitz SA, Hu Y, OBrien N, Finn RS. Current approaches and future directions in the treatment of HER2-positive breast cancer. Cancer Treat Rev 2013; 39:219-229
    • (2013) Cancer Treat Rev , vol.39 , pp. 219-229
    • Hurvitz, S.A.1    Hu, Y.2    Obrien, N.3    Finn, R.S.4
  • 4
    • 84879927236 scopus 로고    scopus 로고
    • Trastuzumab plus adjuvant chemotherapy for HER2-positive breast cancer: Final planned joint analysis of overall survival from NSABP B-31 and NCCTG N9831
    • Romond E, Suman VJ, Jeong J-H, et al. Trastuzumab plus adjuvant chemotherapy for HER2-positive breast cancer: Final planned joint analysis of overall survival from NSABP B-31 and NCCTG N9831. Cancer Res 2012; 72 (Suppl 3); Abstract S5-5
    • (2012) Cancer Res , vol.72 , Issue.SUPPL. 3
    • Romond, E.1    Suman, V.J.2    Jeong, J.-H.3
  • 5
    • 80053539103 scopus 로고    scopus 로고
    • Adjuvant trastuzumab in HER2- positive breast cancer
    • Slamon D, Eiermann W, Robert N, et al. Adjuvant trastuzumab in HER2- positive breast cancer. N Engl J Med 2011; 365:1273-1283
    • (2011) N Engl J Med , vol.365 , pp. 1273-1283
    • Slamon, D.1    Eiermann, W.2    Robert, N.3
  • 6
    • 79952041937 scopus 로고    scopus 로고
    • Treatment with trastuzumab for 1 year after adjuvant chemotherapy in patients with HER2-positive early breast cancer: A 4-year follow-up of a randomised controlled trial
    • Gianni L, Dafni U, Gelber R, et al. Treatment with trastuzumab for 1 year after adjuvant chemotherapy in patients with HER2-positive early breast cancer: a 4-year follow-up of a randomised controlled trial. Lancet Oncol 2011; 12:236-244
    • (2011) Lancet Oncol , vol.12 , pp. 236-244
    • Gianni, L.1    Dafni, U.2    Gelber, R.3
  • 7
    • 84872386782 scopus 로고    scopus 로고
    • HERA TRIAL: 2 years versus 1 year of trastuzumab after adjuvant chemotherapy in women with HER2-positive early breast cancer at 8 years of median follow up
    • Goldhirsch A, Piccart-Gebhart MJ, Procter M, et al. HERA TRIAL: 2 years versus 1 year of trastuzumab after adjuvant chemotherapy in women with HER2-positive early breast cancer at 8 years of median follow up. Cancer Res 2012; 72 (Suppl 3); Abstract S5-2
    • (2012) Cancer Res , vol.72 , Issue.SUPPL. 3
    • Goldhirsch, A.1    Piccart-Gebhart, M.J.2    Procter, M.3
  • 8
    • 84879780559 scopus 로고    scopus 로고
    • 6 months versus 12 months of adjuvant trastuzumab for patients with HER2-positive early breast cancer (PHARE): A randomised phase 3 trial
    • Pivot X, Romieu G, Debled M, et al. 6 months versus 12 months of adjuvant trastuzumab for patients with HER2-positive early breast cancer (PHARE): a randomised phase 3 trial. Lancet Oncol 2013; 14:741-748
    • (2013) Lancet Oncol , vol.14 , pp. 741-748
    • Pivot, X.1    Romieu, G.2    Debled, M.3
  • 9
    • 84869125207 scopus 로고    scopus 로고
    • Seven-year follow-up assessment of cardiac function in NSABP B-31, a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel (ACP) with ACP plus trastuzumab as adjuvant therapy for patients with node-positive, human epidermal growth factor receptor 2-positive breast cancer
    • Romond EH, Jeong JH, Rastogi P, et al. Seven-year follow-up assessment of cardiac function in NSABP B-31, a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel (ACP) with ACP plus trastuzumab as adjuvant therapy for patients with node-positive, human epidermal growth factor receptor 2-positive breast cancer. J Clin Oncol 2012; 30:3792-3799
    • (2012) J Clin Oncol , vol.30 , pp. 3792-3799
    • Romond, E.H.1    Jeong, J.H.2    Rastogi, P.3
  • 10
    • 84881105772 scopus 로고    scopus 로고
    • Role of cardioprotective therapy for prevention of cardiotoxicity with chemotherapy: A systematic review and meta-analysis
    • Kalam K, Marwick TH. Role of cardioprotective therapy for prevention of cardiotoxicity with chemotherapy: A systematic review and meta-analysis. Eur J Cancer 2013; 49:2900-2909
    • (2013) Eur J Cancer , vol.49 , pp. 2900-2909
    • Kalam, K.1    Marwick, T.H.2
  • 11
    • 84874657287 scopus 로고    scopus 로고
    • Benefit of adjuvant trastuzumab-based chemotherapy in T1ab node-negative HER2-overexpressing breast carcinomas: A multicenter retrospective series
    • Rodrigues MJ, Peron J, Frénel JS, et al. Benefit of adjuvant trastuzumab-based chemotherapy in T1ab node-negative HER2-overexpressing breast carcinomas: a multicenter retrospective series. Ann Oncol 2013; 24:916-924
    • (2013) Ann Oncol , vol.24 , pp. 916-924
    • Rodrigues, M.J.1    Peron, J.2    Frénel, J.S.3
  • 12
    • 84862303759 scopus 로고    scopus 로고
    • Definition and impact of pathologic complete response on prognosis after neoadjuvant chemotherapy in various intrinsic breast cancer subtypes
    • von Minckwitz G, Untch M, Blohmer JU, et al. Definition and impact of pathologic complete response on prognosis after neoadjuvant chemotherapy in various intrinsic breast cancer subtypes. J Clin Oncol 2012; 30:1796-1804
    • (2012) J Clin Oncol , vol.30 , pp. 1796-1804
    • Von Minckwitz, G.1    Untch, M.2    Blohmer, J.U.3
  • 13
    • 84881239243 scopus 로고    scopus 로고
    • Pathologic complete response to neoadjuvant chemotherapy with trastuzumab predicts for improved survival in women with HER2-overexpressing breast cancer
    • Kim MM, Allen P, Gonzalez-Angulo AM, et al. Pathologic complete response to neoadjuvant chemotherapy with trastuzumab predicts for improved survival in women with HER2-overexpressing breast cancer. Ann Oncol 2013; 24:1999-2004
    • (2013) Ann Oncol , vol.24 , pp. 1999-2004
    • Kim, M.M.1    Allen, P.2    Gonzalez-Angulo, A.M.3
  • 14
    • 77957771125 scopus 로고    scopus 로고
    • Lapatinib plus capecitabine in women with HER-2-positive advanced breast cancer: Final survival analysis of a phase III randomized trial
    • Cameron D, Casey M, Oliva C, et al. Lapatinib plus capecitabine in women with HER-2-positive advanced breast cancer: final survival analysis of a phase III randomized trial. Oncologist 2010; 15:924-934
    • (2010) Oncologist , vol.15 , pp. 924-934
    • Cameron, D.1    Casey, M.2    Oliva, C.3
  • 15
    • 84862914692 scopus 로고    scopus 로고
    • Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer
    • Baselga J, Cortés J, Kim SB, et al. Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. N Engl J Med 2012; 366:109-119
    • (2012) N Engl J Med , vol.366 , pp. 109-119
    • Baselga, J.1    Cortés, J.2    Kim, S.B.3
  • 16
    • 84876970810 scopus 로고    scopus 로고
    • Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): Overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study
    • Swain SM, Kim SB, Cortes J, et al. Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study. Lancet Oncol 2013; 14:461-471
    • (2013) Lancet Oncol , vol.14 , pp. 461-471
    • Swain, S.M.1    Kim, S.B.2    Cortes, J.3
  • 17
    • 84856444501 scopus 로고    scopus 로고
    • Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (Gepar- Quinto, GBG 44): A randomised phase 3 trial
    • Untch M, Loibl S, Bischoff J, et al. Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (Gepar- Quinto, GBG 44): a randomised phase 3 trial. Lancet Oncol 2012; 13:135-144
    • (2012) Lancet Oncol , vol.13 , pp. 135-144
    • Untch, M.1    Loibl, S.2    Bischoff, J.3
  • 18
    • 84857236823 scopus 로고    scopus 로고
    • Lapatinib with trastuzumab for HER2- positive early breast cancer (NeoALTTO): A randomised, open-label, multicentre, phase 3 trial
    • Baselga J, Bradbury I, Eidtmann H, et al. Lapatinib with trastuzumab for HER2- positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial. Lancet 2012; 379:633-640
    • (2012) Lancet , vol.379 , pp. 633-640
    • Baselga, J.1    Bradbury, I.2    Eidtmann, H.3
  • 19
    • 84864018421 scopus 로고    scopus 로고
    • Preoperative chemotherapy plus trastuzumab, lapatinib, or both in human epidermal growth factor receptor 2-positive operable breast cancer: Results of the randomized phase II CHER-LOB study
    • Guarneri V, Frassoldati A, Bottini A, et al. Preoperative chemotherapy plus trastuzumab, lapatinib, or both in human epidermal growth factor receptor 2-positive operable breast cancer: results of the randomized phase II CHER-LOB study. J Clin Oncol 2012; 30:1989-1995
    • (2012) J Clin Oncol , vol.30 , pp. 1989-1995
    • Guarneri, V.1    Frassoldati, A.2    Bottini, A.3
  • 20
    • 80052895926 scopus 로고    scopus 로고
    • Correlation of molecular effects and pathologic complete response to preoperative lapatinib and trastuzumab, separately and combined prior to neoadjuvant breast cancer chemotherapy
    • (May 20 Supplement)
    • Holmes FA, Nagarwala YM, Espina VS, et al. Correlation of molecular effects and pathologic complete response to preoperative lapatinib and trastuzumab, separately and combined prior to neoadjuvant breast cancer chemotherapy. J Clin Oncol 2011; 29:. No 15-suppl (May 20 Supplement), Abstract 506
    • (2011) J Clin Oncol , vol.29 , Issue.15 SUPPL. , pp. 506
    • Holmes, F.A.1    Nagarwala, Y.M.2    Espina, V.S.3
  • 21
    • 84885416696 scopus 로고    scopus 로고
    • Clinical and translational results of CALGB 40601: A neoadjuvant phase III trial of weekly paclitaxel and trastuzumab with or without lapatinib for HER2-positive breast cancer
    • Carey LA, Berry DA, Ollila D, et al. Clinical and translational results of CALGB 40601: a neoadjuvant phase III trial of weekly paclitaxel and trastuzumab with or without lapatinib for HER2-positive breast cancer. J Clin Oncol 2013; 31 (Suppl); Abstract 500
    • (2013) J Clin Oncol , vol.31 , Issue.SUPPL. , pp. 500
    • Carey, L.A.1    Berry, D.A.2    Ollila, D.3
  • 22
    • 84855297353 scopus 로고    scopus 로고
    • Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): A randomised multicentre, open-label, phase 2 trial
    • Gianni L, Pienkowski T, Im YH, et al. Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial. Lancet Oncol 2012; 13:25-32
    • (2012) Lancet Oncol , vol.13 , pp. 25-32
    • Gianni, L.1    Pienkowski, T.2    Im, Y.H.3
  • 23
    • 84883359410 scopus 로고    scopus 로고
    • Pertuzumab plus trastuzumab in combination with standard neoadjuvant anthracycline-containing and anthracycline- free chemotherapy regimens in patients with HER2-positive early breast cancer: A randomized phase II cardiac safety study (TRYPHAENA)
    • Schneeweiss A, Chia S, Hickish T, et al. Pertuzumab plus trastuzumab in combination with standard neoadjuvant anthracycline-containing and anthracycline- free chemotherapy regimens in patients with HER2-positive early breast cancer: a randomized phase II cardiac safety study (TRYPHAENA). Ann Oncol 2013; 24:2278-2284
    • (2013) Ann Oncol , vol.24 , pp. 2278-2284
    • Schneeweiss, A.1    Chia, S.2    Hickish, T.3
  • 24
    • 79951974161 scopus 로고    scopus 로고
    • Phase III randomized study comparing docetaxel plus trastuzumab with vinorelbine plus trastuzumab as first-line therapy of metastatic or locally advanced human epidermal growth factor receptor 2-positive breast cancer: The HERNATA study
    • Andersson M, Lidbrink E, Bjerre K, et al. Phase III randomized study comparing docetaxel plus trastuzumab with vinorelbine plus trastuzumab as first-line therapy of metastatic or locally advanced human epidermal growth factor receptor 2-positive breast cancer: the HERNATA study. J Clin Oncol 2011; 29:264-271
    • (2011) J Clin Oncol , vol.29 , pp. 264-271
    • Andersson, M.1    Lidbrink, E.2    Bjerre, K.3
  • 25
    • 84878192141 scopus 로고    scopus 로고
    • First-line treatment patterns and clinical outcomes in patients withHER2-positive and hormone receptor-positive metastatic breast cancer from registHER
    • Tripathy D, Kaufman PA, Brufsky AM, et al. First-line treatment patterns and clinical outcomes in patients withHER2-positive and hormone receptor-positive metastatic breast cancer from registHER. Oncologist 2013; 18:501-510
    • (2013) Oncologist , vol.18 , pp. 501-510
    • Tripathy, D.1    Kaufman, P.A.2    Brufsky, A.M.3
  • 26
    • 65349110371 scopus 로고    scopus 로고
    • Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: A German Breast Group 26/Breast International Group 03-05 study
    • von Minckwitz G, du Bois A, Schmidt M, et al. Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: a German Breast Group 26/Breast International Group 03-05 study. J Clin Oncol 2009; 27:1999-2006
    • (2009) J Clin Oncol , vol.27 , pp. 1999-2006
    • Von Minckwitz, G.1    Du Bois, A.2    Schmidt, M.3
  • 27
    • 84875148538 scopus 로고    scopus 로고
    • A pooled analysis of 2618 patients treated with trastuzumab beyond progression for advanced breast cancer
    • Petrelli F, Barni S. A pooled analysis of 2618 patients treated with trastuzumab beyond progression for advanced breast cancer. Clin Breast Cancer 2013; 13:81-97
    • (2013) Clin Breast Cancer , vol.13 , pp. 81-97
    • Petrelli, F.1    Barni, S.2
  • 28
    • 84864066561 scopus 로고    scopus 로고
    • Overall survival benefit with lapatinib in combination with trastuzumab for patients with human epidermal growth factor receptor 2-positive metastatic breast cancer: Final results from the EGF104900 Study
    • Blackwell KL, Burstein HJ, Storniolo AM, et al. Overall survival benefit with lapatinib in combination with trastuzumab for patients with human epidermal growth factor receptor 2-positive metastatic breast cancer: final results from the EGF104900 Study. J Clin Oncol 2012; 30:2585-2592
    • (2012) J Clin Oncol , vol.30 , pp. 2585-2592
    • Blackwell, K.L.1    Burstein, H.J.2    Storniolo, A.M.3
  • 29
    • 84876011018 scopus 로고    scopus 로고
    • Phase ii randomized study of trastuzumab emtansine versus trastuzumab plus docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer
    • Hurvitz SA, Dirix L, Kocsis J, et al. Phase ii randomized study of trastuzumab emtansine versus trastuzumab plus docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer. J Clin Oncol 2013; 31:1157-1163
    • (2013) J Clin Oncol , vol.31 , pp. 1157-1163
    • Hurvitz, S.A.1    Dirix, L.2    Kocsis, J.3
  • 30
    • 84868520609 scopus 로고    scopus 로고
    • Trastuzumab emtansine for HER2-positive advanced breast cancer
    • Verma S, Miles D, Gianni L, et al. Trastuzumab emtansine for HER2-positive advanced breast cancer. N Engl J Med 2012; 367:1783-1791
    • (2012) N Engl J Med , vol.367 , pp. 1783-1791
    • Verma, S.1    Miles, D.2    Gianni, L.3
  • 31
    • 84885420714 scopus 로고    scopus 로고
    • Phase III, randomized, double-blind, placebo-controlled multicenter trial of daily everolimus plus weekly trastuzumab and vinorelbine in trastuzumab- resistant, advanced breast cancer (BOLERO-3)
    • ORegan R, Ozguroglu M, Andre F, et al. Phase III, randomized, double-blind, placebo-controlled multicenter trial of daily everolimus plus weekly trastuzumab and vinorelbine in trastuzumab- resistant, advanced breast cancer (BOLERO-3). J Clin Oncol 2013; 31 (Suppl); abstract 505
    • (2013) J Clin Oncol , vol.31 , Issue.SUPPL. , pp. 505
    • Oregan, R.1    Ozguroglu, M.2    Andre, F.3
  • 32
    • 84884644183 scopus 로고    scopus 로고
    • Health-related quality-of-life assessment in CLEOPATRA, a phase III study combining pertuzumab with trastuzumab and docetaxel in metastatic breast cancer
    • Cortés J, Baselga J, Im YH, et al. Health-related quality-of-life assessment in CLEOPATRA, a phase III study combining pertuzumab with trastuzumab and docetaxel in metastatic breast cancer. Ann Oncol 2013; 24:2630-2635
    • (2013) Ann Oncol , vol.24 , pp. 2630-2635
    • Cortés, J.1    Baselga, J.2    Im, Y.H.3
  • 33
    • 84884718594 scopus 로고    scopus 로고
    • Emerging approaches for treating HER2-positive metastatic breast cancer beyond trastuzumab
    • Gradishar WJ. Emerging approaches for treating HER2-positive metastatic breast cancer beyond trastuzumab. Ann Oncol 2013; 24:2492-2500.
    • (2013) Ann Oncol , vol.24 , pp. 2492-2492
    • Gradishar, W.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.