-
1
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
D.J. Slamon, G.M. Clark, S.G. Wong Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene Science 235 1987 177 182
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
-
2
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
D.J. Slamon, B. Leyland-Jones, S. Shak Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2 N Engl J Med 344 2001 783 792
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
3
-
-
56549113680
-
A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: Updated efficacy and biomarker analyses
-
D. Cameron, M. Casey, M. Press A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses Breast Cancer Res Treat 112 2008 533 543
-
(2008)
Breast Cancer Res Treat
, vol.112
, pp. 533-543
-
-
Cameron, D.1
Casey, M.2
Press, M.3
-
4
-
-
84868520609
-
Trastuzumab emtansine for HER2-positive advanced breast cancer
-
S. Verma, D. Miles, L. Gianni Trastuzumab emtansine for HER2-positive advanced breast cancer N Engl J Med 367 2012 1783 1791
-
(2012)
N Engl J Med
, vol.367
, pp. 1783-1791
-
-
Verma, S.1
Miles, D.2
Gianni, L.3
-
5
-
-
77949884661
-
Randomized study of lapatinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumab-refractory metastatic breast cancer
-
K.L. Blackwell, H.J. Burstein, A.M. Storniolo Randomized study of lapatinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumab-refractory metastatic breast cancer J Clin Oncol 28 2010 1124 1130
-
(2010)
J Clin Oncol
, vol.28
, pp. 1124-1130
-
-
Blackwell, K.L.1
Burstein, H.J.2
Storniolo, A.M.3
-
6
-
-
77949903478
-
Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy
-
J. Baselga, K.A. Gelmon, S. Verma Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy J Clin Oncol 28 2010 1138 1144
-
(2010)
J Clin Oncol
, vol.28
, pp. 1138-1144
-
-
Baselga, J.1
Gelmon, K.A.2
Verma, S.3
-
7
-
-
65349110371
-
Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: A german breast group 26/breast international group 03-05 study
-
G. von Minckwitz, A. du Bois, M. Schmidt Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: a german breast group 26/breast international group 03-05 study J Clin Oncol 27 2009 1999 2006
-
(2009)
J Clin Oncol
, vol.27
, pp. 1999-2006
-
-
Von Minckwitz, G.1
Du Bois, A.2
Schmidt, M.3
-
9
-
-
0037231194
-
Prolonged administration of weekly paclitaxel and trastuzumab in patients with advanced breast cancer
-
C. Christodoulou, G. Klouvas, A. Pateli Prolonged administration of weekly paclitaxel and trastuzumab in patients with advanced breast cancer Anticancer Res 23 2003 737 744
-
(2003)
Anticancer Res
, vol.23
, pp. 737-744
-
-
Christodoulou, C.1
Klouvas, G.2
Pateli, A.3
-
10
-
-
0041696794
-
Continuation of trastuzumab beyond disease progression is feasible and safe in patients with metastatic breast cancer: A retrospective analysis of 80 cases by the Hellenic Cooperative Oncology Group
-
G. Fountzilas, E. Razis, D. Tsavdaridis Continuation of trastuzumab beyond disease progression is feasible and safe in patients with metastatic breast cancer: a retrospective analysis of 80 cases by the Hellenic Cooperative Oncology Group Clin Breast Cancer 4 2003 120 125
-
(2003)
Clin Breast Cancer
, vol.4
, pp. 120-125
-
-
Fountzilas, G.1
Razis, E.2
Tsavdaridis, D.3
-
11
-
-
0642281050
-
Combination of trastuzumab and vinorelbine in metastatic breast cancer
-
Y. Suzuki, Y. Tokuda, Y. Saito Combination of trastuzumab and vinorelbine in metastatic breast cancer Jpn J Clin Oncol 33 2003 514 517
-
(2003)
Jpn J Clin Oncol
, vol.33
, pp. 514-517
-
-
Suzuki, Y.1
Tokuda, Y.2
Saito, Y.3
-
12
-
-
3042676349
-
Use of trastuzumab beyond disease progression: Observations from a retrospective review of case histories
-
K.A. Gelmon, J. Mackey, S. Verma Use of trastuzumab beyond disease progression: observations from a retrospective review of case histories Clin Breast Cancer 5 2004 52 58
-
(2004)
Clin Breast Cancer
, vol.5
, pp. 52-58
-
-
Gelmon, K.A.1
MacKey, J.2
Verma, S.3
-
13
-
-
1842614245
-
Safety of treatment of metastatic breast cancer with trastuzumab beyond disease progression
-
D. Tripathy, D.J. Slamon, M. Cobleigh Safety of treatment of metastatic breast cancer with trastuzumab beyond disease progression J Clin Oncol 22 2004 1063 1070
-
(2004)
J Clin Oncol
, vol.22
, pp. 1063-1070
-
-
Tripathy, D.1
Slamon, D.J.2
Cobleigh, M.3
-
14
-
-
28344441711
-
Trastuzumab associated with successive cytotoxic therapies beyond disease progression in metastatic breast cancer
-
J.A. García-Sáenz, M. Martín, J. Puente Trastuzumab associated with successive cytotoxic therapies beyond disease progression in metastatic breast cancer Clin Breast Cancer 6 2005 325 329
-
(2005)
Clin Breast Cancer
, vol.6
, pp. 325-329
-
-
García-Sáenz, J.A.1
Martín, M.2
Puente, J.3
-
15
-
-
27244438620
-
Prolonged survival of patients receiving trastuzumab beyond disease progression for HER2 overexpressing metastatic breast cancer (MBC)
-
H.J. Stemmler, S. Kahlert, W. Siekiera Prolonged survival of patients receiving trastuzumab beyond disease progression for HER2 overexpressing metastatic breast cancer (MBC) Onkologie 28 2005 582 586
-
(2005)
Onkologie
, vol.28
, pp. 582-586
-
-
Stemmler, H.J.1
Kahlert, S.2
Siekiera, W.3
-
16
-
-
33748557778
-
Trastuzumab in combination with gemcitabine and vinorelbine as second-line therapy for HER-2/neu overexpressing metastatic breast cancer
-
A. Morabito, R. Longo, D. Gattuso Trastuzumab in combination with gemcitabine and vinorelbine as second-line therapy for HER-2/neu overexpressing metastatic breast cancer Oncol Rep 16 2006 393 398
-
(2006)
Oncol Rep
, vol.16
, pp. 393-398
-
-
Morabito, A.1
Longo, R.2
Gattuso, D.3
-
17
-
-
33645538673
-
Analysis of trastuzumab and chemotherapy in advanced breast cancer after the failure of at least one earlier combination: An observational study
-
R. Bartsch, C. Wenzel, D. Hussian Analysis of trastuzumab and chemotherapy in advanced breast cancer after the failure of at least one earlier combination: an observational study BMC Cancer 6 2006 63
-
(2006)
BMC Cancer
, vol.6
, pp. 63
-
-
Bartsch, R.1
Wenzel, C.2
Hussian, D.3
-
18
-
-
34248633217
-
Efficacy and safety of combined trastuzumab and paclitaxel therapy as a second-line treatment in women with metastatic breast cancer: A single institutional experience
-
K. Furukawa, Y. Ito, S. Takahashi Efficacy and safety of combined trastuzumab and paclitaxel therapy as a second-line treatment in women with metastatic breast cancer: a single institutional experience Breast Cancer 13 2006 329 333
-
(2006)
Breast Cancer
, vol.13
, pp. 329-333
-
-
Furukawa, K.1
Ito, Y.2
Takahashi, S.3
-
19
-
-
35748940673
-
Safety and activity of trastuzumab-containing therapies for the treatment of metastatic breast cancer: Our long-term clinical experience (GOIM study)
-
V. Adamo, T. Franchina, B. Adamo Safety and activity of trastuzumab-containing therapies for the treatment of metastatic breast cancer: our long-term clinical experience (GOIM study) Ann Oncol 18 Suppl 6 2007 vi11 vi15
-
(2007)
Ann Oncol
, vol.18
, Issue.SUPPL. 6
-
-
Adamo, V.1
Franchina, T.2
Adamo, B.3
-
20
-
-
34548543191
-
Capecitabine and trastuzumab in heavily pretreated metastatic breast cancer
-
R. Bartsch, C. Wenzel, G. Altorjai Capecitabine and trastuzumab in heavily pretreated metastatic breast cancer J Clin Oncol 25 2007 3853 3858
-
(2007)
J Clin Oncol
, vol.25
, pp. 3853-3858
-
-
Bartsch, R.1
Wenzel, C.2
Altorjai, G.3
-
21
-
-
49749094419
-
Trastuzumab and gemcitabine as salvage therapy in heavily pre-treated patients with metastatic breast cancer
-
R. Bartsch, C. Wenzel, S.P. Gampenrieder Trastuzumab and gemcitabine as salvage therapy in heavily pre-treated patients with metastatic breast cancer Cancer Chemother Pharmacol 62 2008 903 910
-
(2008)
Cancer Chemother Pharmacol
, vol.62
, pp. 903-910
-
-
Bartsch, R.1
Wenzel, C.2
Gampenrieder, S.P.3
-
22
-
-
58149235344
-
Retrospective evaluation of clinical outcomes in patients with HER2-positive advanced breast cancer progressing on trastuzumab-based therapy in the pre-lapatinib era
-
F. Montemurro, S. Redana, G. Viale Retrospective evaluation of clinical outcomes in patients with HER2-positive advanced breast cancer progressing on trastuzumab-based therapy in the pre-lapatinib era Clin Breast Cancer 8 2008 436 442
-
(2008)
Clin Breast Cancer
, vol.8
, pp. 436-442
-
-
Montemurro, F.1
Redana, S.2
Viale, G.3
-
23
-
-
65849322821
-
Continuing trastuzumab beyond disease progression: Outcomes analysis in patients with metastatic breast cancer
-
G. Cancello, E. Montagna, D. D'Agostino Continuing trastuzumab beyond disease progression: outcomes analysis in patients with metastatic breast cancer Breast Cancer Res 10 2008 R60
-
(2008)
Breast Cancer Res
, vol.10
, pp. 60
-
-
Cancello, G.1
Montagna, E.2
D'Agostino, D.3
-
24
-
-
70450270720
-
Predicting for activity of second-line trastuzumab-based therapy in her2-positive advanced breast cancer
-
R. Bartsch, C. De Vries, U. Pluschnig Predicting for activity of second-line trastuzumab-based therapy in her2-positive advanced breast cancer BMC Cancer 9 2009 367
-
(2009)
BMC Cancer
, vol.9
, pp. 367
-
-
Bartsch, R.1
De Vries, C.2
Pluschnig, U.3
-
25
-
-
77149137362
-
Survival of patients with HER2+ metastatic breast cancer and use of trastuzumab following progression: Analysis of registHER
-
H. Rugo, P. Kaufman, E. Tan-Chiu Survival of patients with HER2+ metastatic breast cancer and use of trastuzumab following progression: analysis of registHER Cancer Res 69 Suppl S 2009 2
-
(2009)
Cancer Res
, vol.69
, Issue.SUPPL. S
, pp. 2
-
-
Rugo, H.1
Kaufman, P.2
Tan-Chiu, E.3
-
26
-
-
70350757862
-
Weekly gemcitabine and trastuzumab in the treatment of patients with HER2-overexpressing metastatic breast cancer
-
D.A. Yardley, H.A. Burris 3rd, S. Hanson Weekly gemcitabine and trastuzumab in the treatment of patients with HER2-overexpressing metastatic breast cancer Clin Breast Cancer 9 2009 178 183
-
(2009)
Clin Breast Cancer
, vol.9
, pp. 178-183
-
-
Yardley, D.A.1
Burris III, H.A.2
Hanson, S.3
-
27
-
-
77956793546
-
Efficacy of trastuzumab in routine clinical practice and after progression for metastatic breast cancer patients: The observational Hermine study
-
J.M. Extra, E.C. Antoine, A. Vincent-Salomon Efficacy of trastuzumab in routine clinical practice and after progression for metastatic breast cancer patients: the observational Hermine study Oncologist 15 2010 799 809
-
(2010)
Oncologist
, vol.15
, pp. 799-809
-
-
Extra, J.M.1
Antoine, E.C.2
Vincent-Salomon, A.3
-
28
-
-
77249179256
-
Time to first tumor progression as outcome predictor of a second trasuzumab-based therapy beyond progression in HER-2 positive metastatic breast cancer
-
G. Metro, D. Giannarelli, D. Gemma Time to first tumor progression as outcome predictor of a second trasuzumab-based therapy beyond progression in HER-2 positive metastatic breast cancer Breast J 16 2010 66 72
-
(2010)
Breast J
, vol.16
, pp. 66-72
-
-
Metro, G.1
Giannarelli, D.2
Gemma, D.3
-
29
-
-
72449139053
-
Randomized phase III trial of trastuzumab monotherapy followed by trastuzumab plus docetaxel versus trastuzumab plus docetaxel as first-line therapy in patients with HER2-positive metastatic breast cancer: The JO17360 Trial Group
-
K. Inoue, K. Nakagami, M. Mizutani Randomized phase III trial of trastuzumab monotherapy followed by trastuzumab plus docetaxel versus trastuzumab plus docetaxel as first-line therapy in patients with HER2-positive metastatic breast cancer: the JO17360 Trial Group Breast Cancer Res Treat 119 2010 127 136
-
(2010)
Breast Cancer Res Treat
, vol.119
, pp. 127-136
-
-
Inoue, K.1
Nakagami, K.2
Mizutani, M.3
-
30
-
-
79960853935
-
Trastuzumab beyond progression in HER2-positive advanced breast cancer: The Royal Marsden experience
-
T. Waddell, A. Kotsori, A. Constantinidou Trastuzumab beyond progression in HER2-positive advanced breast cancer: the Royal Marsden experience Br J Cancer 104 2011 1675 1679
-
(2011)
Br J Cancer
, vol.104
, pp. 1675-1679
-
-
Waddell, T.1
Kotsori, A.2
Constantinidou, A.3
-
31
-
-
79959226810
-
Increased overall survival independent of RECIST response in metastatic breast cancer patients continuing trastuzumab treatment: Evidence from a retrospective study
-
M. Campiglio, R. Bufalino, M. Sandri Increased overall survival independent of RECIST response in metastatic breast cancer patients continuing trastuzumab treatment: evidence from a retrospective study Breast Cancer Res Treat 128 2011 147 154
-
(2011)
Breast Cancer Res Treat
, vol.128
, pp. 147-154
-
-
Campiglio, M.1
Bufalino, R.2
Sandri, M.3
-
32
-
-
80054974600
-
Trastuzumab treatment beyond progression in advanced breast cancer: Patterns of care in six Swiss breast cancer centers
-
J. Huober, M. Baumann, C. Rochlitz Trastuzumab treatment beyond progression in advanced breast cancer: patterns of care in six Swiss breast cancer centers Oncology 81 2011 160 166
-
(2011)
Oncology
, vol.81
, pp. 160-166
-
-
Huober, J.1
Baumann, M.2
Rochlitz, C.3
-
33
-
-
84855207735
-
Time to first tumor progression as a predictor of efficacy of continued treatment with trastuzumab beyond progression in human epidermal growth factor receptor 2-positive metastatic breast cancer
-
M. Hayashi, Y. Okumura, T. Osako Time to first tumor progression as a predictor of efficacy of continued treatment with trastuzumab beyond progression in human epidermal growth factor receptor 2-positive metastatic breast cancer Int J Clin Oncol 16 2011 694 700
-
(2011)
Int J Clin Oncol
, vol.16
, pp. 694-700
-
-
Hayashi, M.1
Okumura, Y.2
Osako, T.3
-
34
-
-
80053362290
-
Trastuzumab beyond progression: Overall survival analysis of the GBG 26/BIG 3-05 phase III study in HER2-positive breast cancer
-
G. von Minckwitz, K. Schwedler, M. Schmidt Trastuzumab beyond progression: overall survival analysis of the GBG 26/BIG 3-05 phase III study in HER2-positive breast cancer Eur J Cancer 47 2011 2273 2281
-
(2011)
Eur J Cancer
, vol.47
, pp. 2273-2281
-
-
Von Minckwitz, G.1
Schwedler, K.2
Schmidt, M.3
-
35
-
-
84903897183
-
(EGF111438): An open label randomized phase III study comparing the incidence of CNS metastases in patients (pts) with HER2+ metastatic breast cancer (MBC), treated with Lapatinib plus capecitabine (LC) versus trastuzumab plus capecitabine (TC) [Abstract]
-
LBA5-PR
-
X. Pivot, V. Semiglazov, B. Zurawski (EGF111438): an open label randomized phase III study comparing the incidence of CNS metastases in patients (pts) with HER2+ metastatic breast cancer (MBC), treated with Lapatinib plus capecitabine (LC) versus trastuzumab plus capecitabine (TC) [Abstract] Ann Oncol 23 Suppl 9 2012 ixe2 LBA5-PR
-
(2012)
Ann Oncol
, vol.23
, Issue.SUPPL. 9
, pp. 2
-
-
Pivot, X.1
Semiglazov, V.2
Zurawski, B.3
-
36
-
-
77954963893
-
Use of trastuzumab in HER2-positive metastatic breast cancer beyond disease progression: A systematic review of published studies
-
A. Mannocci, E. De Feo, C. de Waure Use of trastuzumab in HER2-positive metastatic breast cancer beyond disease progression: a systematic review of published studies Tumori 96 2010 385 391
-
(2010)
Tumori
, vol.96
, pp. 385-391
-
-
Mannocci, A.1
De Feo, E.2
De Waure, C.3
-
37
-
-
53149153173
-
Do HER-2 positive metastatic breast cancer patients benefit from the use of trastuzumab beyond disease progression? A mono-institutional experience and systematic review of observational studies
-
A. Fabi, G. Metro, G. Ferretti Do HER-2 positive metastatic breast cancer patients benefit from the use of trastuzumab beyond disease progression? A mono-institutional experience and systematic review of observational studies Breast 17 2008 499 505
-
(2008)
Breast
, vol.17
, pp. 499-505
-
-
Fabi, A.1
Metro, G.2
Ferretti, G.3
-
38
-
-
73949105921
-
Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptor-positive metastatic breast cancer: Results from the randomized phase III TAnDEM study
-
B. Kaufman, J.R. Mackey, M.R. Clemens Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptor-positive metastatic breast cancer: results from the randomized phase III TAnDEM study J Clin Oncol 27 2009 5529 5537
-
(2009)
J Clin Oncol
, vol.27
, pp. 5529-5537
-
-
Kaufman, B.1
MacKey, J.R.2
Clemens, M.R.3
-
39
-
-
0032850677
-
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
-
M.A. Cobleigh, C.L. Vogel, D. Tripathy Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease J Clin Oncol 17 1999 2639 2648
-
(1999)
J Clin Oncol
, vol.17
, pp. 2639-2648
-
-
Cobleigh, M.A.1
Vogel, C.L.2
Tripathy, D.3
-
40
-
-
84864028260
-
Comparison of overall survival between the early use and delayed use of trastuzumab therapy groups: A retrospective analysis of 128 patients with HER-2-positive advanced breast cancer
-
Y.X. Shi, Y.T. Tan, Z.Y. Yuan Comparison of overall survival between the early use and delayed use of trastuzumab therapy groups: a retrospective analysis of 128 patients with HER-2-positive advanced breast cancer Med Oncol 29 2012 39 47
-
(2012)
Med Oncol
, vol.29
, pp. 39-47
-
-
Shi, Y.X.1
Tan, Y.T.2
Yuan, Z.Y.3
-
41
-
-
79956277409
-
Continued use of trastuzumab beyond disease progression in the national comprehensive cancer network: Should we practice ahead of the evidence?
-
Y.N. Wong, R.A. Ottesen, M.E. Hughes Continued use of trastuzumab beyond disease progression in the national comprehensive cancer network: should we practice ahead of the evidence? Oncologist 16 2011 559 565
-
(2011)
Oncologist
, vol.16
, pp. 559-565
-
-
Wong, Y.N.1
Ottesen, R.A.2
Hughes, M.E.3
|