Integrated multiplatform method for in vitro quantitative assessment of cellular uptake for fluorescent polymer nanoparticles

Nanotechnology

Volumn 25, Issue 4, 2014, Pages

  Ferrari, Raffaele ^a   Lupi, Monica ^b   Falcetta, Francesca ^b   Bigini, Paolo ^b   Paolella, Katia ^b   Fiordaliso, Fabio ^b   Bisighini, Cinzia ^b   Salmona, Mario ^b   D'Incalci, Maurizio ^b   Morbidelli, Massimo ^c   Moscatelli, Davide ^a   Ubezio, Paolo ^b  

^a POLITECNICO DI MILANO   (Italy)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c ETH ZURICH   (Switzerland)

Author keywords

cellular uptake; endocytosis; flow cytometry; imaging; nanoparticles

Indexed keywords

CELLULAR INTERNALIZATION; CELLULAR UPTAKE; EFFICIENT DRUG DELIVERY; ENDOCYTOSIS; EXPERIMENTAL TECHNIQUES; INTRACELLULAR CONCENTRATION; QUANTITATIVE ASSESSMENTS; QUANTITATIVE EVALUATION;

BIOCOMPATIBILITY; CALIBRATION; CELLS; CYTOLOGY; DRUG DELIVERY; EMULSIFICATION; FLOW CYTOMETRY; FREE RADICAL POLYMERIZATION; IMAGING TECHNIQUES; MOLECULAR BIOLOGY; NANOPARTICLES; PARTICLE SIZE ANALYSIS;

FLUORESCENCE;

BIOMATERIAL; DRUG CARRIER; FLUORESCENT DYE; FREE RADICAL; NANOPARTICLE; POLYMER; RHODAMINE; RHODAMINE B;

ANIMAL; ARTICLE; CHEMISTRY; CONFOCAL MICROSCOPY; EQUIPMENT; EXPERIMENTAL MAMMARY NEOPLASM; FEMALE; FLOW CYTOMETRY; KINETICS; METHODOLOGY; MOUSE; PARTICLE SIZE; PATHOLOGY; SPECTROFLUOROMETRY; TUMOR CELL LINE;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELL LINE, TUMOR; DRUG CARRIERS; FEMALE; FLOW CYTOMETRY; FLUORESCENT DYES; FREE RADICALS; KINETICS; MAMMARY NEOPLASMS, ANIMAL; MICE; MICROSCOPY, CONFOCAL; NANOPARTICLES; PARTICLE SIZE; POLYMERS; RHODAMINES; SPECTROMETRY, FLUORESCENCE;

EID: 84891838360     PISSN: 09574484     EISSN: 13616528     Source Type: Journal    
DOI: 10.1088/0957-4484/25/4/045102     Document Type: Article

References (30)

1. Brigger I, Dubernet C and Couvreur P 2002 Adv. Drug Deliv. Rev. 54 631-51 (Pubitemid 35247520)
2. Bartlett D W, Su H, Hildebrandt I J, Weber W A and Davis M E 2007 Proc. Natl Acad. Sci. USA 104 15549-54 (Pubitemid 47502954)
3. Lorenz M R, Holzapfel V, Musyanovych A, Nothelfer K, Walther P, Frank H, Landfester K, Schrezenmeier H and Mailander V 2006 Biomaterials 27 2820-8 (Pubitemid 43165751)
4. dos Santos T, Varela J, Lynch I, Salvati A and Dawson K A 2011 Small 7 3341-9
5. Lorenz S, Hauser C P, Autenrieth B, Weiss C K, Landfester K and Mailänder V 2010 Macromol. Biosci. 10 1034-42
6. Smith P J, Giroud M, Wiggins H L, Gower F, Thorley J A, Stolpe B, Mazzolini J, Dyson R J and Rappoport J Z 2012 Int. J. Nanomed. 7 2045-55
7. Cho E C, Zhang Q and Xia Y 2011 Nature Nanotechnol. 6 385-91
8. Cho E C, Xie J W, Wurm P A and Xia Y N 2009 Nano Lett. 9 1080-4
9. Chithrani B D, Ghazani A A and Chan W C 2006 Nano Lett. 6 662-8
10. Ferrari R, Yu Y, Morbidelli M, Hutchinson R A and Moscatelli D 2011 Macromolecules 44 9205-12
11. Ferrari R, Yu Y, Lattuada M, Storti G, Morbidelli M and Moscatelli D 2012 Macromol. Chem. Phys. 213 2012-8
12. Norakankorn C, Pan Q M, Rempel G L and Kiatkamjornwong S J 2009 J. Appl. Polym. Sci. 113 375-82
13. Dossi M, Ferrari R, Dragoni L, Martignoni C, Gaetani P, D'Incalci M, Morbidelli M and Moscatelli D 2013 Macromol. Mater. Eng. 298 730-9
14. Cova L et al 2013 Nanotechnology 24 245603
15. Musyanovych A, Dausend J, Dass M, Walther P, Mailander V and Landfester K 2011 Acta Biomater. 7 4160-8
16. Shen Z L and Andersson S B 2011 IEEE Trans. Control Syst. Technol. 19 1269-78
17. Salvati A, Aberg C, dos Santos T, Varela J, Pinto P, Lynch I and Dawson K A 2011 Nanomedicine 7 818-26
18. Kim J A, Aberg C, Salvati A and Dawson K A 2012 Nature Nanotechnol. 7 62-8
19. Lee R J and Low P S 1994 J. Biol. Chem. 369 3198-204
20. Massignani M, LoPresti C, Blanazs A, Madsen J, Armes S P, Lewis A L and Battaglia G 2009 Small 5 2424-32
21. LoPresti C et al 2011 ACS Nano 5 1775-84
22. Summers H D, Brown M R, Holton M D, Tonkin J A, Hondow N, Brown A P, Brydson R and Rees P 2013 ACS Nano 7 6129-37
23. Zucker R M, Massaro E J, Sanders K M, Degn L L and Boyes W K 2010 Cytometry A 77A 677-85
24. Sajjadi S and Yianneskis M 2010 Polym. React. Eng. 11 715-36
25. Lesniak A, Campbell A, Monopoli M P, Lynch I, Salvati A and Dawson K A 2010 Biomaterials 31 9511-8
26. Desai M P, Labhasetwar V, Walter E, Levy R J and Amido G L 1997 Pharm. Res. 14 1568-73 (Pubitemid 28009208)
27. Mailander V and Landfester K 2009 Biomacromolecules 10 2379-400
28. Tao K, Fang M, Alroy J and Sahagian G G 2008 BMC Cancer 8 228
29. Chithrani B D and Chan W C W 2007 Nano Lett. 7 1542-50 (Pubitemid 47140422)
30. Iversen T G, Skotland T and Sandvig K 2011 Nano Today 6 176-85