-
1
-
-
84891814124
-
Natural Product Chemistry and Cancer Drug Discovery
-
2nd ed. Neidle, S. Academic Press, Part II
-
Huryn, D. M. and Wipf, P. Natural Product Chemistry and Cancer Drug Discovery. In Cancer Drug Discovery, 2nd ed.; Neidle, S., Ed.; Academic Press, 2013; Part II, pp 91-120.
-
(2013)
Cancer Drug Discovery
, pp. 91-120
-
-
Huryn, D.M.1
Wipf, P.2
-
4
-
-
79955554738
-
-
Clemons, P. A.; Wilson, J. A.; Dančik, V.; Muller, S.; Carrinski, H. A.; Wagner, B. K.; Koehler, A. N.; Schreiber, S. L. Proc. Natl. Acad. Sci. U.S.A. 2011, 108, 6817-6822
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 6817-6822
-
-
Clemons, P.A.1
Wilson, J.A.2
Dančik, V.3
Muller, S.4
Carrinski, H.A.5
Wagner, B.K.6
Koehler, A.N.7
Schreiber, S.L.8
-
5
-
-
78650459806
-
-
Clemons, P. A.; Bodycombe, N. E.; Carrinski, H. A.; Wilson, J. A.; Shamji, A. F.; Wagner, B. K.; Koehler, A. N.; Schreiber, S. L. Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 18787-18792
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 18787-18792
-
-
Clemons, P.A.1
Bodycombe, N.E.2
Carrinski, H.A.3
Wilson, J.A.4
Shamji, A.F.5
Wagner, B.K.6
Koehler, A.N.7
Schreiber, S.L.8
-
6
-
-
71049126548
-
-
Lovering, F.; Bikker, J.; Humblet, C. J. Med. Chem. 2009, 52, 6752-6756
-
(2009)
J. Med. Chem.
, vol.52
, pp. 6752-6756
-
-
Lovering, F.1
Bikker, J.2
Humblet, C.3
-
7
-
-
84856449974
-
-
Camp, D.; Davis, R. A.; Campitelli, M.; Ebdon, J.; Quinn, R. J. J. Nat. Prod. 2012, 75, 72-81
-
(2012)
J. Nat. Prod.
, vol.75
, pp. 72-81
-
-
Camp, D.1
Davis, R.A.2
Campitelli, M.3
Ebdon, J.4
Quinn, R.J.5
-
8
-
-
84970921627
-
-
Isolation: Bernauer, K.; Englert, G.; Vetter, W.; Weiss, E. Helv. Chim. Acta 1969, 52, 1886-1905
-
(1969)
Helv. Chim. Acta
, vol.52
, pp. 1886-1905
-
-
Bernauer, K.1
Englert, G.2
Vetter, W.3
Weiss, E.4
-
9
-
-
33846134670
-
-
Short review: Szabó, L. F. ARKIVOC 2007, 7, 280-290
-
(2007)
ARKIVOC
, vol.7
, pp. 280-290
-
-
Szabó, L.F.1
-
10
-
-
38949138457
-
-
Wender, P. A.; Verma, V. A.; Paxton, T. J.; Pillow, T. H. Acc. Chem. Res. 2008, 41, 40-49
-
(2008)
Acc. Chem. Res.
, vol.41
, pp. 40-49
-
-
Wender, P.A.1
Verma, V.A.2
Paxton, T.J.3
Pillow, T.H.4
-
11
-
-
34547444477
-
-
Rubin, M.; Rubina, M.; Gevorgyan, V. Chem. Rev. 2007, 107, 3117-3179
-
(2007)
Chem. Rev.
, vol.107
, pp. 3117-3179
-
-
Rubin, M.1
Rubina, M.2
Gevorgyan, V.3
-
12
-
-
84867794012
-
-
Trost, B. M.; Morris, P. J.; Sprague, S. J. J. Am. Chem. Soc. 2012, 134, 17823-17831
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 17823-17831
-
-
Trost, B.M.1
Morris, P.J.2
Sprague, S.J.3
-
13
-
-
84862580124
-
-
Wang, H. N.; Yang, W.; Liu, H.; Wang, W.; Li, H. Org. Biomol. Chem. 2012, 10, 5032-5035
-
(2012)
Org. Biomol. Chem.
, vol.10
, pp. 5032-5035
-
-
Wang, H.N.1
Yang, W.2
Liu, H.3
Wang, W.4
Li, H.5
-
14
-
-
84858685710
-
-
Dieskau, A. P.; Holzwarth, M. S.; Plietker, B. J. Am. Chem. Soc. 2012, 134, 5048-5051
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 5048-5051
-
-
Dieskau, A.P.1
Holzwarth, M.S.2
Plietker, B.3
-
15
-
-
79851493299
-
-
Jiao, L.; Lin, M.; Yu, Z. X. J. Am. Chem. Soc. 2011, 133, 447-461
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 447-461
-
-
Jiao, L.1
Lin, M.2
Yu, Z.X.3
-
17
-
-
77949870022
-
-
Li, Q.; Jiang, G. J.; Jiao, L.; Yu, Z. X. Org. Lett. 2010, 12, 1332-1335
-
(2010)
Org. Lett.
, vol.12
, pp. 1332-1335
-
-
Li, Q.1
Jiang, G.J.2
Jiao, L.3
Yu, Z.X.4
-
18
-
-
76249087412
-
-
Jiao, L.; Lin, M.; Yu, Z.-X. Chem. Commun. 2010, 46, 1059-1061
-
(2010)
Chem. Commun.
, vol.46
, pp. 1059-1061
-
-
Jiao, L.1
Lin, M.2
Yu, Z.-X.3
-
19
-
-
44949202612
-
-
Jiao, L.; Ye, S. Y.; Yu, Z. X. J. Am. Chem. Soc. 2008, 130, 7178-7179
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 7178-7179
-
-
Jiao, L.1
Ye, S.Y.2
Yu, Z.X.3
-
20
-
-
0001360672
-
-
Feldman, K. S.; Berven, H. M.; Romanelli, A. L.; Parvez, M. J. Org. Chem. 1993, 58, 6851-6856
-
(1993)
J. Org. Chem.
, vol.58
, pp. 6851-6856
-
-
Feldman, K.S.1
Berven, H.M.2
Romanelli, A.L.3
Parvez, M.4
-
21
-
-
0002116890
-
-
Feldman, K. S.; Romanelli, A. L.; Ruckle, R. E.; Jean, G. J. Org. Chem. 1992, 57, 100-110
-
(1992)
J. Org. Chem.
, vol.57
, pp. 100-110
-
-
Feldman, K.S.1
Romanelli, A.L.2
Ruckle, R.E.3
Jean, G.4
-
23
-
-
0001105181
-
-
Feldman, K. S.; Romanelli, A. L.; Ruckle, R. E.; Miller, R. F. J. Am. Chem. Soc. 1988, 110, 3300-3302
-
(1988)
J. Am. Chem. Soc.
, vol.110
, pp. 3300-3302
-
-
Feldman, K.S.1
Romanelli, A.L.2
Ruckle, R.E.3
Miller, R.F.4
-
24
-
-
0000031536
-
-
Miura, K.; Fugami, K.; Oshima, K.; Utimoto, K. Tetrahedron Lett. 1988, 29, 5135-5138
-
(1988)
Tetrahedron Lett.
, vol.29
, pp. 5135-5138
-
-
Miura, K.1
Fugami, K.2
Oshima, K.3
Utimoto, K.4
-
25
-
-
70350316746
-
-
Preliminary studies: Guthrie, D. B.; Geib, S. J.; Curran, D. P. J. Am. Chem. Soc. 2009, 131, 15492-15500
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 15492-15500
-
-
Guthrie, D.B.1
Geib, S.J.2
Curran, D.P.3
-
27
-
-
0025856173
-
-
First total synthesis: Overman, L. E.; Robertson, G. M.; Robichaud, A. J. J. Am. Chem. Soc. 1991, 113, 2598-2610
-
(1991)
J. Am. Chem. Soc.
, vol.113
, pp. 2598-2610
-
-
Overman, L.E.1
Robertson, G.M.2
Robichaud, A.J.3
-
28
-
-
64049110842
-
-
Selig, P.; Herdtweck, E.; Bach, T. Chem.-Eur. J. 2009, 15, 3509-3525
-
(2009)
Chem. - Eur. J.
, vol.15
, pp. 3509-3525
-
-
Selig, P.1
Herdtweck, E.2
Bach, T.3
-
29
-
-
79953232753
-
-
Hayashi, Y.; Inagaki, F.; Mukai, C. Org. Lett. 2011, 13, 1778-1780
-
(2011)
Org. Lett.
, vol.13
, pp. 1778-1780
-
-
Hayashi, Y.1
Inagaki, F.2
Mukai, C.3
-
31
-
-
84856032177
-
-
Coldham, I.; Burrell, A. J. M.; Guerrand, H. D. S.; Watson, L.; Martin, N. G.; Oram, N. Beil. J. Org. Chem. 2012, 8, 107-111
-
(2012)
Beil. J. Org. Chem.
, vol.8
, pp. 107-111
-
-
Coldham, I.1
Burrell, A.J.M.2
Guerrand, H.D.S.3
Watson, L.4
Martin, N.G.5
Oram, N.6
-
32
-
-
28244448289
-
-
The route is patterned after a synthesis of 9b in: Kiewel, K.; Luo, Z. S.; Sulikowski, G. A. Org. Lett. 2005, 7, 5163-5165
-
(2005)
Org. Lett.
, vol.7
, pp. 5163-5165
-
-
Kiewel, K.1
Luo, Z.S.2
Sulikowski, G.A.3
-
34
-
-
84891798163
-
-
Samples of all the final products have been deposited in the UPitt CMLD Center library. For synthetic and biological probe aims of Chemical Methodology and Library Development Centers (CMLDs)
-
Samples of all the final products have been deposited in the UPitt CMLD Center library. For synthetic and biological probe aims of Chemical Methodology and Library Development Centers (CMLDs), see: http://www.nigms.nih.gov/Research/ FeaturedPrograms/CMLD/.
-
-
-
-
35
-
-
0031024171
-
-
Lipinski, C. A.; Lombardo, F.; Dominya, B. W.; Feeney, P. J. Adv. Drug Delivery Rev. 1997, 23, 3-25
-
(1997)
Adv. Drug Delivery Rev.
, vol.23
, pp. 3-25
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominya, B.W.3
Feeney, P.J.4
|