Synthesis of highly enantioenriched 3,4-dihydroquinolin-2-ones by 6-Exo-trig radical cyclizations of axially chiral α-halo-ortho-alkenyl anilides

Journal of the American Chemical Society

Volumn 131, Issue 42, 2009, Pages 15492-15500

  Guthrie, David B ^a   Geib, Steven J ^a   Curran, Dennis P ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKENYL; ANILIDES; AXIAL CHIRALITY; CHIRALITY TRANSFER; CYCLIZATIONS; DIASTEREO-SELECTIVITY; HIGH FIDELITY; HIGH YIELD; RADICAL CYCLIZATIONS; RADICAL REACTIONS; REACTIVE SPECIES; STEREOCENTERS;

CHIRALITY; CYCLIZATION; ENANTIOMERS; REACTION KINETICS; STEREOCHEMISTRY; STEREOSELECTIVITY;

AMIDES;

3,4 DIHYDROQUINOLIN 2 ONES; AMIDE; ANILIDE; FUNCTIONAL GROUP; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHIRALITY; CYCLIZATION; ELECTRON TRANSPORT; ENANTIOMER; ENANTIOSELECTIVITY; STEREOCHEMISTRY; SUBSTITUTION REACTION; SYNTHESIS;

ALKENES; ANILIDES; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; FREE RADICALS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; QUINOLONES; STEREOISOMERISM;

EID: 70350316746     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9066282     Document Type: Article

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