-
1
-
-
20044372326
-
In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells
-
Messmer BT, Messmer D, Allen SL, Kolitz JE, Kudalkar P, et al. (2005) In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells. Journal of Clinical Investigation 115: 755-764.
-
(2005)
Journal of Clinical Investigation
, vol.115
, pp. 755-764
-
-
Messmer, B.T.1
Messmer, D.2
Allen, S.L.3
Kolitz, J.E.4
Kudalkar, P.5
-
2
-
-
77956801193
-
Expanded and highly active proliferation centers identify a histological subtype of chronic lymphocytic leukemia ("accelerated" chronic lymphocytic leukemia) with aggressive clinical behavior
-
Giné E, Martinez A, Villamor N, Lopez-Guillermo A, Camos M, et al. (2010) Expanded and highly active proliferation centers identify a histological subtype of chronic lymphocytic leukemia ("accelerated" chronic lymphocytic leukemia) with aggressive clinical behavior. Haematologica 95: 1526-1533.
-
(2010)
Haematologica
, vol.95
, pp. 1526-1533
-
-
Giné, E.1
Martinez, A.2
Villamor, N.3
Lopez-Guillermo, A.4
Camos, M.5
-
3
-
-
35948946952
-
Homeostatic chemokines increase survival of B-chronic lymphocytic leukemia cells through inactivation of transcription factor FOXO3a
-
Ticchioni M, Essafi M, Jeandel PY, Davi F, Cassuto JP, et al. (2007) Homeostatic chemokines increase survival of B-chronic lymphocytic leukemia cells through inactivation of transcription factor FOXO3a. Oncogene 26: 7081-7091.
-
(2007)
Oncogene
, vol.26
, pp. 7081-7091
-
-
Ticchioni, M.1
Essafi, M.2
Jeandel, P.Y.3
Davi, F.4
Cassuto, J.P.5
-
4
-
-
84875456366
-
A Combination of Cytokines Rescues Highly Purified Leukemic CLL B-Cells from Spontaneous Apoptosis In Vitro
-
Ghamlouch H, Ouled-Haddou H, Damaj G, Royer B, Gubler B, et al. (2013) A Combination of Cytokines Rescues Highly Purified Leukemic CLL B-Cells from Spontaneous Apoptosis In Vitro. PLoS ONE 8: e60370.
-
(2013)
PLoS ONE
, vol.8
-
-
Ghamlouch, H.1
Ouled-Haddou, H.2
Damaj, G.3
Royer, B.4
Gubler, B.5
-
5
-
-
0037306842
-
Differential signaling via surface IgM is associated with VH gene mutational status and CD38 expression in chronic lymphocytic leukemia
-
Lanham S, Hamblin T, Oscier D, Ibbotson R, Stevenson F, et al. (2003) Differential signaling via surface IgM is associated with VH gene mutational status and CD38 expression in chronic lymphocytic leukemia. Blood 101: 1087-1093.
-
(2003)
Blood
, vol.101
, pp. 1087-1093
-
-
Lanham, S.1
Hamblin, T.2
Oscier, D.3
Ibbotson, R.4
Stevenson, F.5
-
6
-
-
0242298176
-
Role of the microenvironment in chronic lymphocytic leukaemia
-
Caligaris-Cappio F (2003) Role of the microenvironment in chronic lymphocytic leukaemia. British journal of haematology 123: 380-388.
-
(2003)
British Journal of Haematology
, vol.123
, pp. 380-388
-
-
Caligaris-Cappio, F.1
-
7
-
-
70350734809
-
The microenvironment in mature B-cell malignancies: A target for new treatment strategies
-
Burger JA, Ghia P, Rosenwald A, Caligaris-Cappio F (2009) The microenvironment in mature B-cell malignancies: a target for new treatment strategies. Blood 114: 3367-3375.
-
(2009)
Blood
, vol.114
, pp. 3367-3375
-
-
Burger, J.A.1
Ghia, P.2
Rosenwald, A.3
Caligaris-Cappio, F.4
-
8
-
-
80051786984
-
A novel role of the CX3CR1/CX3CL1 system in the cross-talk between chronic lymphocytic leukemia cells and tumor microenvironment
-
Ferretti E, Bertolotto M, Deaglio S, Tripodo C, Ribatti D, et al. (2011) A novel role of the CX3CR1/CX3CL1 system in the cross-talk between chronic lymphocytic leukemia cells and tumor microenvironment. Leukemia 25: 1268-1277.
-
(2011)
Leukemia
, vol.25
, pp. 1268-1277
-
-
Ferretti, E.1
Bertolotto, M.2
Deaglio, S.3
Tripodo, C.4
Ribatti, D.5
-
9
-
-
0037406968
-
ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia
-
Crespo M, Bosch F, Villamor N, Bellosillo B, Colomer D, et al. (2003) ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia. New England Journal of Medicine 348: 1764-1775.
-
(2003)
New England Journal of Medicine
, vol.348
, pp. 1764-1775
-
-
Crespo, M.1
Bosch, F.2
Villamor, N.3
Bellosillo, B.4
Colomer, D.5
-
10
-
-
4143105617
-
ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia
-
Rassenti LZ, Huynh L, Toy TL, Chen L, Keating MJ, et al. (2004) ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia. New England Journal of Medicine 351: 893-901.
-
(2004)
New England Journal of Medicine
, vol.351
, pp. 893-901
-
-
Rassenti, L.Z.1
Huynh, L.2
Toy, T.L.3
Chen, L.4
Keating, M.J.5
-
11
-
-
0842276675
-
ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia
-
Dürig J, Nückel H, Cremer M, Führer A, Halfmeyer K, et al. (2003) ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia. Leukemia 17: 2426-2434.
-
(2003)
Leukemia
, vol.17
, pp. 2426-2434
-
-
Dürig, J.1
Nückel, H.2
Cremer, M.3
Führer, A.4
Halfmeyer, K.5
-
12
-
-
33646433940
-
ZAP-70 expression is associated with enhanced ability to respond to migratory and survival signals in B-cell chronic lymphocytic leukemia (B-CLL)
-
Richardson SJ, Matthews C, Catherwood MA, Alexander HD, Carey BS, et al. (2006) ZAP-70 expression is associated with enhanced ability to respond to migratory and survival signals in B-cell chronic lymphocytic leukemia (B-CLL). Blood 107: 3584.
-
(2006)
Blood
, vol.107
, pp. 3584
-
-
Richardson, S.J.1
Matthews, C.2
Catherwood, M.A.3
Alexander, H.D.4
Carey, B.S.5
-
13
-
-
37049023065
-
CD38 and ZAP-70 are functionally linked and mark CLL cells with high migratory potential
-
Deaglio S, Vaisitti T, Aydin S, Bergui L, D'Arena G, et al. (2007) CD38 and ZAP-70 are functionally linked and mark CLL cells with high migratory potential. Blood 110: 4012-4021.
-
(2007)
Blood
, vol.110
, pp. 4012-4021
-
-
Deaglio, S.1
Vaisitti, T.2
Aydin, S.3
Bergui, L.4
D'Arena, G.5
-
14
-
-
70349237504
-
B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: Specific targeting with a novel spleen tyrosine kinase inhibitor, R406
-
Quiroga MP, Balakrishnan K, Kurtova AV, Sivina M, Keating MJ, et al. (2009) B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406. Blood 114: 1029-1037.
-
(2009)
Blood
, vol.114
, pp. 1029-1037
-
-
Quiroga, M.P.1
Balakrishnan, K.2
Kurtova, A.V.3
Sivina, M.4
Keating, M.J.5
-
15
-
-
78751684268
-
Chronic lymphocytic leukemia cells receive RAF-dependent survival signals in response to CXCL12 that are sensitive to inhibition by sorafenib
-
Messmer D, Fecteau JF, O'Hayre M, Bharati IS, Handel TM, et al. (2011) Chronic lymphocytic leukemia cells receive RAF-dependent survival signals in response to CXCL12 that are sensitive to inhibition by sorafenib. Blood 117: 882-889.
-
(2011)
Blood
, vol.117
, pp. 882-889
-
-
Messmer, D.1
Fecteau, J.F.2
O'Hayre, M.3
Bharati, I.S.4
Handel, T.M.5
-
16
-
-
80054844491
-
ZAP-70 enhances migration of malignant B lymphocytes toward CCL21 by inducing CCR7 expression via IgM-ERK1/2 activation
-
Calpe E, Codony C, Baptista MJ, Abrisqueta P, Carpio C, et al. (2011) ZAP-70 enhances migration of malignant B lymphocytes toward CCL21 by inducing CCR7 expression via IgM-ERK1/2 activation. Blood 118: 4401-4410.
-
(2011)
Blood
, vol.118
, pp. 4401-4410
-
-
Calpe, E.1
Codony, C.2
Baptista, M.J.3
Abrisqueta, P.4
Carpio, C.5
-
17
-
-
66749095444
-
Gene expression profiling reveals differences in microenvironment interaction between patients with chronic lymphocytic leukemia expressing high versus low ZAP70 mRNA
-
Stamatopoulos B, Haibe-Kains B, Equeter C, Meuleman N, Sorée A, et al. (2009) Gene expression profiling reveals differences in microenvironment interaction between patients with chronic lymphocytic leukemia expressing high versus low ZAP70 mRNA. Haematologica 94: 790-799.
-
(2009)
Haematologica
, vol.94
, pp. 790-799
-
-
Stamatopoulos, B.1
Haibe-Kains, B.2
Equeter, C.3
Meuleman, N.4
Sorée, A.5
-
18
-
-
74249107839
-
Recruitment of PKC-βII to lipid rafts mediates apoptosis-resistance in chronic lymphocytic leukemia expressing ZAP-70
-
Zum Büschenfelde CM, Wagner M, Lutzny G, Oelsner M, Feuerstacke Y, et al. (2009) Recruitment of PKC-βII to lipid rafts mediates apoptosis-resistance in chronic lymphocytic leukemia expressing ZAP-70. Leukemia 24: 141-152.
-
(2009)
Leukemia
, vol.24
, pp. 141-152
-
-
Zum Büschenfelde, C.M.1
Wagner, M.2
Lutzny, G.3
Oelsner, M.4
Feuerstacke, Y.5
-
19
-
-
0033519236
-
B cell antigen receptor engagement inhibits stromal cell-derived factor (SDF)-1α chemotaxis and promotes protein kinase C (PKC)-induced internalization of CXCR4
-
Guinamard R, Signoret N, Ishiai M, Marsh M, Kurosaki T, et al. (1999) B cell antigen receptor engagement inhibits stromal cell-derived factor (SDF)-1α chemotaxis and promotes protein kinase C (PKC)-induced internalization of CXCR4. The Journal of experimental medicine 189: 1461.
-
(1999)
The Journal of Experimental Medicine
, vol.189
, pp. 1461
-
-
Guinamard, R.1
Signoret, N.2
Ishiai, M.3
Marsh, M.4
Kurosaki, T.5
-
20
-
-
0037085752
-
BCR ligation reprograms B cells for migration to the T zone and B-cell follicle sequentially
-
Casamayor-Pallejà M, Mondière P, Verschelde C, Bella C, Defrance T (2002) BCR ligation reprograms B cells for migration to the T zone and B-cell follicle sequentially. Blood 99: 1913-1921.
-
(2002)
Blood
, vol.99
, pp. 1913-1921
-
-
Casamayor-Pallejà, M.1
Mondière, P.2
Verschelde, C.3
Bella, C.4
Defrance, T.5
-
21
-
-
50949128066
-
BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgVH unmutated chronic lymphocytic leukemia (CLL) cells
-
Guarini A, Chiaretti S, Tavolaro S, Maggio R, Peragine N, et al. (2008) BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgVH unmutated chronic lymphocytic leukemia (CLL) cells. Blood 112: 782-792.
-
(2008)
Blood
, vol.112
, pp. 782-792
-
-
Guarini, A.1
Chiaretti, S.2
Tavolaro, S.3
Maggio, R.4
Peragine, N.5
-
22
-
-
69249120197
-
Down-regulation of CXCR4 and CD62L in chronic lymphocytic leukemia cells is triggered by B-cell receptor ligation and associated with progressive disease
-
Vlad A, Deglesne PA, Letestu R, Saint-Georges S, Chevallier N, et al. (2009) Down-regulation of CXCR4 and CD62L in chronic lymphocytic leukemia cells is triggered by B-cell receptor ligation and associated with progressive disease. Cancer research 69: 6387.
-
(2009)
Cancer Research
, vol.69
, pp. 6387
-
-
Vlad, A.1
Deglesne, P.A.2
Letestu, R.3
Saint-Georges, S.4
Chevallier, N.5
-
23
-
-
0024562238
-
Reproducible establishment of hemopoietic supportive stromal cell lines from murine bone marrow
-
Itoh K, Tezuka H, Sakoda H, Konno M, Nagata K, et al. (1989) Reproducible establishment of hemopoietic supportive stromal cell lines from murine bone marrow. Exp Hematol 17: 145-53
-
(1989)
Exp Hematol
, vol.17
, pp. 145-153
-
-
Itoh, K.1
Tezuka, H.2
Sakoda, H.3
Konno, M.4
Nagata, K.5
-
24
-
-
34948858867
-
Targeting CD37-positive lymphoid malignancies with a novel engineered small modular immunopharmaceutical
-
Zhao X, Lapalombella R, Joshi T, Cheney C, Gowda A, et al. (2007) Targeting CD37-positive lymphoid malignancies with a novel engineered small modular immunopharmaceutical. Blood 110: 2569-2577.
-
(2007)
Blood
, vol.110
, pp. 2569-2577
-
-
Zhao, X.1
Lapalombella, R.2
Joshi, T.3
Cheney, C.4
Gowda, A.5
-
25
-
-
28844468487
-
Effective therapy of human lymphoma xenografts with a novel recombinant ribonuclease/ anti-CD74 humanized IgG4 antibody immunotoxin
-
Chang CH, Sapra P, Vanama SS, Hansen HJ, Horak ID, et al. (2005) Effective therapy of human lymphoma xenografts with a novel recombinant ribonuclease/ anti-CD74 humanized IgG4 antibody immunotoxin. Blood 106: 4308-4314.
-
(2005)
Blood
, vol.106
, pp. 4308-4314
-
-
Chang, C.H.1
Sapra, P.2
Vanama, S.S.3
Hansen, H.J.4
Horak, I.D.5
-
26
-
-
0029833943
-
A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)
-
Bleul CC, Fuhlbrigge RC, Casasnovas JM, Aiuti A, Springer TA (1996) A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). The Journal of experimental medicine 184: 1101-1109.
-
(1996)
The Journal of Experimental Medicine
, vol.184
, pp. 1101-1109
-
-
Bleul, C.C.1
Fuhlbrigge, R.C.2
Casasnovas, J.M.3
Aiuti, A.4
Springer, T.A.5
-
27
-
-
77952419807
-
CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells
-
Vaisitti T, Aydin S, Rossi D, Cottino F, Bergui L, et al. (2010) CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells. Leukemia 24: 958-969.
-
(2010)
Leukemia
, vol.24
, pp. 958-969
-
-
Vaisitti, T.1
Aydin, S.2
Rossi, D.3
Cottino, F.4
Bergui, L.5
-
28
-
-
23944488816
-
Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells
-
Burger M, Hartmann T, Krome M, Rawluk J, Tamamura H, et al. (2005) Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells. Blood 106: 1824-1830.
-
(2005)
Blood
, vol.106
, pp. 1824-1830
-
-
Burger, M.1
Hartmann, T.2
Krome, M.3
Rawluk, J.4
Tamamura, H.5
-
29
-
-
23044514711
-
Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1α
-
Nishio M, Endo T, Tsukada N, Ohata J, Kitada S, et al. (2005) Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1α. Blood 106: 1012-1020.
-
(2005)
Blood
, vol.106
, pp. 1012-1020
-
-
Nishio, M.1
Endo, T.2
Tsukada, N.3
Ohata, J.4
Kitada, S.5
-
30
-
-
0036606772
-
CXCR4 neutralization, a novel therapeutic approach for non-Hodgkin's lymphoma
-
Bertolini F, Dell'Agnola C, Mancuso P, Rabascio C, Burlini A, et al. (2002) CXCR4 neutralization, a novel therapeutic approach for non-Hodgkin's lymphoma. Cancer Research 62: 3106-3112.
-
(2002)
Cancer Research
, vol.62
, pp. 3106-3112
-
-
Bertolini, F.1
Dell'Agnola, C.2
Mancuso, P.3
Rabascio, C.4
Burlini, A.5
-
31
-
-
84875212754
-
Xenograft models of chronic lymphocytic leukemia: Problems, pitfalls and future directions
-
Bertilaccio MTS, Scielzo C, Simonetti G, Hacken ET, Apollonio B, et al. (2012) Xenograft models of chronic lymphocytic leukemia: problems, pitfalls and future directions. Leukemia 27: 534-540.
-
(2012)
Leukemia
, vol.27
, pp. 534-540
-
-
Bertilaccio, M.T.S.1
Scielzo, C.2
Simonetti, G.3
Hacken, E.T.4
Apollonio, B.5
-
32
-
-
33847412872
-
ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells
-
Gobessi S, Laurenti L, Longo PG, Sica S, Leone G, et al. (2007) ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells. Blood 109: 2032-2039.
-
(2007)
Blood
, vol.109
, pp. 2032-2039
-
-
Gobessi, S.1
Laurenti, L.2
Longo, P.G.3
Sica, S.4
Leone, G.5
-
33
-
-
0026483786
-
ZAP-70: A 70 kd proteintyrosine kinase that associates with the TCR zeta chain
-
Chan AC, Iwashima M, Turck CW, Weiss A (1992) ZAP-70: a 70 kd proteintyrosine kinase that associates with the TCR zeta chain. Cell 71: 649-662.
-
(1992)
Cell
, vol.71
, pp. 649-662
-
-
Chan, A.C.1
Iwashima, M.2
Turck, C.W.3
Weiss, A.4
-
34
-
-
14944352799
-
ZAP-70 directly enhances IgM signaling in chronic lymphocytic leukemia
-
Chen L, Apgar J, Huynh L, Dicker F, Giago-McGahan T, et al. (2005) ZAP-70 directly enhances IgM signaling in chronic lymphocytic leukemia. Blood 105: 2036-2041.
-
(2005)
Blood
, vol.105
, pp. 2036-2041
-
-
Chen, L.1
Apgar, J.2
Huynh, L.3
Dicker, F.4
Giago-McGahan, T.5
-
35
-
-
41949140313
-
ZAP-70 enhances IgM signaling independent of its kinase activity in chronic lymphocytic leukemia
-
Chen L, Huynh L, Apgar J, Tang L, Rassenti L, et al. (2008) ZAP-70 enhances IgM signaling independent of its kinase activity in chronic lymphocytic leukemia. Blood 111: 2685-2692.
-
(2008)
Blood
, vol.111
, pp. 2685-2692
-
-
Chen, L.1
Huynh, L.2
Apgar, J.3
Tang, L.4
Rassenti, L.5
-
36
-
-
0036566221
-
Signaling through ZAP-70 is required for CXCL12-mediated T-cell transendothelial migration
-
Ticchioni M, Charvet C, Noraz N, Lamy L, Steinberg M, et al. (2002) Signaling through ZAP-70 is required for CXCL12-mediated T-cell transendothelial migration. Blood 99: 3111-3118.
-
(2002)
Blood
, vol.99
, pp. 3111-3118
-
-
Ticchioni, M.1
Charvet, C.2
Noraz, N.3
Lamy, L.4
Steinberg, M.5
-
37
-
-
0037868184
-
Distinct role of ZAP-70 and Src homology 2 domain-containing leukocyte protein of 76 kDa in the prolonged activation of extracellular signal-regulated protein kinase by the stromal cell-derived factor-1α/CXCL12 chemokine
-
Kremer KN, Humphreys TD, Kumar A, Qian NX, Hedin KE (2003) Distinct role of ZAP-70 and Src homology 2 domain-containing leukocyte protein of 76 kDa in the prolonged activation of extracellular signal-regulated protein kinase by the stromal cell-derived factor-1α/CXCL12 chemokine. The Journal of Immunology 171: 360.
-
(2003)
The Journal of Immunology
, vol.171
, pp. 360
-
-
Kremer, K.N.1
Humphreys, T.D.2
Kumar, A.3
Qian, N.X.4
Hedin, K.E.5
-
38
-
-
67049137382
-
Isoform-selective phosphoinositide 3′-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: A novel therapeutic approach
-
Niedermeier M, Hennessy BT, Knight ZA, Henneberg M, Hu J, et al. (2009) Isoform-selective phosphoinositide 3′-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach. Blood 113: 5549-5557.
-
(2009)
Blood
, vol.113
, pp. 5549-5557
-
-
Niedermeier, M.1
Hennessy, B.T.2
Knight, Z.A.3
Henneberg, M.4
Hu, J.5
-
39
-
-
77952886100
-
Spleen tyrosine kinase inhibition prevents chemokine-and integrin-mediated stromal protective effects in chronic lymphocytic leukemia
-
Buchner M, Baer C, Prinz G, Dierks C, Burger M, et al. (2010) Spleen tyrosine kinase inhibition prevents chemokine-and integrin-mediated stromal protective effects in chronic lymphocytic leukemia. Blood 115: 4497-4506.
-
(2010)
Blood
, vol.115
, pp. 4497-4506
-
-
Buchner, M.1
Baer, C.2
Prinz, G.3
Dierks, C.4
Burger, M.5
-
40
-
-
84863011553
-
The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo
-
Ponader S, Chen SS, Buggy JJ, Balakrishnan K, Gandhi V, et al. (2012) The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo. Blood 119: 1182-1189.
-
(2012)
Blood
, vol.119
, pp. 1182-1189
-
-
Ponader, S.1
Chen, S.S.2
Buggy, J.J.3
Balakrishnan, K.4
Gandhi, V.5
-
41
-
-
84858636448
-
The clinically active BTK inhibitor PCI-32765 targets B-cell receptor-and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia
-
De Rooij MFM, Kuil A, Geest CR, Eldering E, Chang BY, et al. (2012) The clinically active BTK inhibitor PCI-32765 targets B-cell receptor-and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia. Blood 119: 2590-4.
-
(2012)
Blood
, vol.119
, pp. 2590-2594
-
-
De Rooij, M.F.M.1
Kuil, A.2
Geest, C.R.3
Eldering, E.4
Chang, B.Y.5
-
42
-
-
84863781222
-
Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration
-
Hoellenriegel J, Coffey GP, Sinha U, Pandey A, Sivina M, et al. (2012) Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration. Leukemia 26: 1576-1583.
-
(2012)
Leukemia
, vol.26
, pp. 1576-1583
-
-
Hoellenriegel, J.1
Coffey, G.P.2
Sinha, U.3
Pandey, A.4
Sivina, M.5
-
43
-
-
84875199467
-
The Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib (PCI-32765) Promotes High Response Rate, Durable Remissions, and Is Tolerable in Treatment Naive (TN) and Relapsed or Refractory (RR) Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) Patients Including Patients with High- Risk (HR) Disease: New and Updated Results of 116 Patients in a Phase Ib/II Study
-
Byrd JC, Furman RR, Coutre S, Flinn IW, Burger JA, et al. (2012) The Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib (PCI-32765) Promotes High Response Rate, Durable Remissions, and Is Tolerable in Treatment Naive (TN) and Relapsed or Refractory (RR) Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) Patients Including Patients with High- Risk (HR) Disease: New and Updated Results of 116 Patients in a Phase Ib/II Study. ASH Annual Meeting Abstracts 120: 189.
-
(2012)
ASH Annual Meeting Abstracts
, vol.120
, pp. 189
-
-
Byrd, J.C.1
Furman, R.R.2
Coutre, S.3
Flinn, I.W.4
Burger, J.A.5
-
44
-
-
79953655788
-
CAL- 101, An Isoform-Selective Inhibitor of Phosphatidylinositol 3-Kinase P110d, Demonstrates Clinical Activity and Pharmacodynamic Effects In Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia
-
Furman RR, Byrd JC, Brown JR, Coutre SE, Benson DM, et al. (2010) CAL- 101, An Isoform-Selective Inhibitor of Phosphatidylinositol 3-Kinase P110d, Demonstrates Clinical Activity and Pharmacodynamic Effects In Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia. ASH Annual Meeting Abstracts 116: 55.
-
(2010)
ASH Annual Meeting Abstracts
, vol.116
, pp. 55
-
-
Furman, R.R.1
Byrd, J.C.2
Brown, J.R.3
Coutre, S.E.4
Benson, D.M.5
-
45
-
-
77951002653
-
Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia
-
Friedberg JW, Sharman J, Sweetenham J, Johnston PB, Vose JM, et al. (2010) Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia. Blood 115: 2578-2585.
-
(2010)
Blood
, vol.115
, pp. 2578-2585
-
-
Friedberg, J.W.1
Sharman, J.2
Sweetenham, J.3
Johnston, P.B.4
Vose, J.M.5
-
46
-
-
34248145362
-
Abdominal Computed Tomography Predicts Progression in Patients With Rai Stage 0 Chronic Lymphocytic Leukemia
-
Muntañola A, Bosch F, Arguis P, Arellano-Rodrigo E, Ayuso C, et al. (2007) Abdominal Computed Tomography Predicts Progression in Patients With Rai Stage 0 Chronic Lymphocytic Leukemia. JCO 25: 1576-1580.
-
(2007)
JCO
, vol.25
, pp. 1576-1580
-
-
Muntañola, A.1
Bosch, F.2
Arguis, P.3
Arellano-Rodrigo, E.4
Ayuso, C.5
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